Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Mary & May 6 Peptide Complex Serum Versus Celimax Dual Barrier Boosting Serum

Mary & May 6 Peptide Complex Serum Versus Celimax Dual Barrier Boosting Serum This anti-aging serum is formulated around Copper Tripeptide-1 and Palmitoyl Pentapeptide-4 to soften the look of wrinkles and refine skin texture. This barrier-repair serum is formu

Mary & May 6 Peptide Complex Serum Versus Celimax Dual Barrier Boosting Serum

This anti-aging serum is formulated around Copper Tripeptide-1 and Palmitoyl Pentapeptide-4 to soften the look of wrinkles and refine skin texture.

This barrier-repair serum is formulated around Panthenol and Ceramide NP to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycereth-26

1,2-Hexanediol

Butylene Glycol

Glycerin

Arginine

Carbomer

Ethylhexylglycerin

Polyglyceryl-10 Laurate

Adenosine

Caprylyl Glycol

Copper Tripeptide-1

Hexapeptide-11

Hexapeptide-9

Palmitoyl Pentapeptide-4

Palmitoyl Tripeptide-1

Tripeptide-1

Water, Glycereth-26, 1,2-Hexanediol, Butylene Glycol, Glycerin, Arginine, Carbomer, Ethylhexylglycerin, Polyglyceryl-10 Laurate, Adenosine, Caprylyl Glycol, Copper Tripeptide-1, Hexapeptide-11, Hexapeptide-9, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Tripeptide-1

Caprylic/Capric Triglyceride

Dipentaerythrityl Hexa C5-9 Acid Esters

Panthenol

C14-22 Alcohols

Glyceryl Stearate

Cetearyl Alcohol

Sorbitan Sesquioleate

C12-20 Alkyl Glucoside

Tromethamine

Heptasodium Hexacarboxymethyl Dipeptide-12

Ceramide NP

2,3-Butanediol

Hydrogenated Lecithin

Biosaccharide Gum-1

Ceramide Ns

Ceramide As

Ceramide AP

Cholesterol

Phytosphingosine

Dipropylene Glycol

Ceramide EOP

Water, Butylene Glycol, Glycerin, Glycereth-26, Caprylic/Capric Triglyceride, 1,2-Hexanediol, Dipentaerythrityl Hexa C5-9 Acid Esters, Panthenol, C14-22 Alcohols, Glyceryl Stearate, Cetearyl Alcohol, Sorbitan Sesquioleate, C12-20 Alkyl Glucoside, Carbomer, Tromethamine, Ethylhexylglycerin, Heptasodium Hexacarboxymethyl Dipeptide-12, Ceramide NP, 2,3-Butanediol, Hydrogenated Lecithin, Biosaccharide Gum-1, Ceramide Ns, Ceramide As, Ceramide AP, Cholesterol, Phytosphingosine, Dipropylene Glycol, Ceramide EOP

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.

It is a humectant and helps add texture to products. It can make your product thicker.

As a humectant, it helps draw moisture from the air to your skin. This helps your skin stay hydrated.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Glycereth-26
  3. 031,2-Hexanediol
  4. 04Butylene Glycol
  5. 05Glycerin
  6. 06Arginine
  7. 07Carbomer
  8. 08Ethylhexylglycerin
  9. 09Polyglyceryl-10 Laurate
  10. 10Adenosine
  11. 11Caprylyl Glycol
  12. 12Copper Tripeptide-1
  13. 13Hexapeptide-11
  14. 14Hexapeptide-9
  15. 15Palmitoyl Pentapeptide-4
  16. 16Palmitoyl Tripeptide-1
  17. 17Tripeptide-1
  18. 18Water, Glycereth-26, 1,2-Hexanediol, Butylene Glycol, Glycerin, Arginine, Carbomer, Ethylhexylglycerin, Polyglyceryl-10 Laurate, Adenosine, Caprylyl Glycol, Copper Tripeptide-1, Hexapeptide-11, Hexapeptide-9, Palmitoyl Pentapeptide-4, Palmitoyl Trip…
  19. 19Centella Asiatica Extract 49%
  20. 20Dipropylene Glycol
Source · skinsort.com
02

Product index

Related product references

Product

MARY & MAY 6 Peptide Complex Serum

MARY & MAY 6 Peptide Complex Serum MARY & MAY 6 Peptide Complex Serum ingredients explained: Purified Water, Glycereth-26, 1,2-Hexanediol, Butylene Glycol, Glycerin, Arginine, Carbomer, Eth…

Source: incidecoder.comView reference →

Product

Mary & May 6 Peptide Complex Serum

Mary & May 6 Peptide Complex Serum Ingredients in Mary & May 6 Peptide Complex Serum explained: benefits, concerns, and detailed analysis of 17 ingredients including Water, Glycereth-26, an…

Source: skinsort.comView reference →
03

Comparison edit

Read side by side