Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Mary & May Calendula Peptide Ageless Sleeping Mask Versus Skin79 Rose Waterful Sleeping Mask

Mary & May Calendula Peptide Ageless Sleeping Mask Versus Skin79 Rose Waterful Sleeping Mask This anti-aging overnight mask is formulated around Acetyl Hexapeptide-8 and Copper Tripeptide-1 to soften the look of wrinkles and refine skin texture. This brighteni

Mary & May Calendula Peptide Ageless Sleeping Mask Versus Skin79 Rose Waterful Sleeping Mask

This anti-aging overnight mask is formulated around Acetyl Hexapeptide-8 and Copper Tripeptide-1 to soften the look of wrinkles and refine skin texture.

This brightening overnight mask is formulated around Niacinamide and Rosa Damascena Flower Water to brighten dull-looking skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Alcohol Denat.

Methylpropanediol

1,2-Hexanediol

Betaine

Dipropylene Glycol

Gardenia Taitensis Callus Extract

Oak Root Extract

Tremella Fuciformis Extract

Centella Asiatica Extract

Ficus Carica Fruit Extract

Orchid Leaf/Root/Stem Extract

Chamomilla Recutita Extract

Chrysanthemum Parthenium Extract

Hydrogenated Lecithin

Sodium Hyaluronate

Panthenol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Glycerin

Tromethamine

Butylene Glycol

Polyglyceryl-10 Laurate

Dextrin

Sodium Phytate

Ceramide NP

Tocopherol

Acetyl Hexapeptide-8

Acetyl Octapeptide-3

Acetyl Tetrapeptide-2

Oligopeptide-6

Tripeptide-1

Copper Tripeptide-1

Hexapeptide-2

Dipeptide-2

Acetyl Tetrapeptide-3

Acetyl Tripeptide-1

Hexapeptide-9

Tripeptide-2

Nonapeptide-1

Pentapeptide-3

Tripeptide-3

Alanine/Histidine/Lysine Polypeptide Copper Hcl

Dipeptide-4

Acetyl Tetrapeptide-5

Palmitoyl Dipeptide-7

Palmitoyl Hexapeptide-12

Palmitoyl Tripeptide-1

Palmitoyl Tripeptide-5

Palmitoyl Pentapeptide-4

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Palmitoyl Tetrapeptide-7

Guaiazulene

Parfum

Ethylhexylglycerin

Water, Alcohol Denat., Methylpropanediol, 1,2-Hexanediol, Betaine, Dipropylene Glycol, Gardenia Taitensis Callus Extract, Oak Root Extract, Tremella Fuciformis Extract, Centella Asiatica Extract, Ficus Carica Fruit Extract, Orchid Leaf/Root/Stem Extract, Chamomilla Recutita Extract, Chrysanthemum Parthenium Extract, Hydrogenated Lecithin, Sodium Hyaluronate, Panthenol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glycerin, Tromethamine, Butylene Glycol, Polyglyceryl-10 Laurate, Dextrin, Sodium Phytate, Ceramide NP, Tocopherol, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Oligopeptide-6, Tripeptide-1, Copper Tripeptide-1, Hexapeptide-2, Dipeptide-2, Acetyl Tetrapeptide-3, Acetyl Tripeptide-1, Hexapeptide-9, Tripeptide-2, Nonapeptide-1, Pentapeptide-3, Tripeptide-3, Alanine/Histidine/Lysine Polypeptide Copper Hcl, Dipeptide-4, Acetyl Tetrapeptide-5, Palmitoyl Dipeptide-7, Palmitoyl Hexapeptide-12, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Pentapeptide-4, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tetrapeptide-7, Guaiazulene, Parfum, Ethylhexylglycerin

Cyclopentasiloxane

Propanediol

Dimethicone

Niacinamide

Dimethicone/PEG-10/15 Crosspolymer

Rosa Damascena Flower Water

Citric Acid

Glycolic Acid

Lactic Acid

Malic Acid

Pyruvic Acid

Tartaric Acid

Trehalose

Malpighia Emarginata Fruit Extract

Terminalia Ferdinandiana Fruit Extract

Euterpe Oleracea Fruit Extract

Ficus Carica Fruit/Leaf Extract

Morus Alba Fruit Extract

Theobroma Cacao Seed Extract

Sodium Citrate

Benzophenone-5

Disodium EDTA

Phenoxyethanol

Chlorphenesin

Sodium Benzoate

Potassium Sorbate

CI 17200

CI 42090

Water, Glycerin, Cyclopentasiloxane, Propanediol, Dimethicone, Niacinamide, Dimethicone/PEG-10/15 Crosspolymer, Butylene Glycol, Rosa Damascena Flower Water, Citric Acid, Glycolic Acid, Lactic Acid, Malic Acid, Pyruvic Acid, Tartaric Acid, Trehalose, Malpighia Emarginata Fruit Extract, Terminalia Ferdinandiana Fruit Extract, Euterpe Oleracea Fruit Extract, Ficus Carica Fruit/Leaf Extract, Morus Alba Fruit Extract, Ceramide NP, Betaine, Theobroma Cacao Seed Extract, Sodium Citrate, Benzophenone-5, Disodium EDTA, Phenoxyethanol, Chlorphenesin, Sodium Benzoate, Potassium Sorbate, CI 17200, CI 42090, Parfum

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.

Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.

Some studies suggest betaine may support making skin tone more even.

Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.

Betaine is also known as trimethylglycine.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

02

Product index

Related product references

03

Comparison edit

Read side by side