MediCube Collagen Night Wrapping Mask Versus Mary & May Calendula Peptide Ageless Sleeping Mask

MediCube Collagen Night Wrapping Mask Versus Mary & May Calendula Peptide Ageless Sleeping Mask

This anti-aging overnight mask is formulated around Niacinamide and Ceramide NP to soften the look of wrinkles and hydrate skin.

This anti-aging overnight mask is formulated around Acetyl Hexapeptide-8 and Copper Tripeptide-1 to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Polyvinyl Alcohol

Glycerin

Agave Americana Stem Extract

Niacinamide

Sodium Hyaluronate

1,2-Hexanediol

Caprylyl Glycol

Polyglyceryl-10 Laurate

Chlorella Vulgaris Extract

Glucose

Butylene Glycol

Ethylhexylglycerin

Fructooligosaccharides

Fructose

Adenosine

Xanthan Gum

Cynanchum Atratum Extract

Caprylic/Capric Triglyceride

Hydrogenated Lecithin

Althaea Rosea Flower Extract

Ceramide NP

Tocopherol

Pancratium Maritimum Extract

Collagen Extract

Sodium Stearoyl Glutamate

Water, Polyvinyl Alcohol, Glycerin, Agave Americana Stem Extract, Niacinamide, Sodium Hyaluronate, 1,2-Hexanediol, Caprylyl Glycol, Polyglyceryl-10 Laurate, Chlorella Vulgaris Extract, Glucose, Butylene Glycol, Ethylhexylglycerin, Fructooligosaccharides, Fructose, Adenosine, Xanthan Gum, Cynanchum Atratum Extract, Caprylic/Capric Triglyceride, Hydrogenated Lecithin, Althaea Rosea Flower Extract, Ceramide NP, Tocopherol, Pancratium Maritimum Extract, Collagen Extract, Sodium Stearoyl Glutamate

Alcohol Denat.

Methylpropanediol

Betaine

Dipropylene Glycol

Gardenia Taitensis Callus Extract

Oak Root Extract

Tremella Fuciformis Extract

Centella Asiatica Extract

Ficus Carica Fruit Extract

Orchid Leaf/Root/Stem Extract

Chamomilla Recutita Extract

Chrysanthemum Parthenium Extract

Panthenol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Tromethamine

Dextrin

Sodium Phytate

Acetyl Hexapeptide-8

Acetyl Octapeptide-3

Acetyl Tetrapeptide-2

Oligopeptide-6

Tripeptide-1

Copper Tripeptide-1

Hexapeptide-2

Dipeptide-2

Acetyl Tetrapeptide-3

Acetyl Tripeptide-1

Hexapeptide-9

Tripeptide-2

Nonapeptide-1

Pentapeptide-3

Tripeptide-3

Alanine/Histidine/Lysine Polypeptide Copper Hcl

Dipeptide-4

Acetyl Tetrapeptide-5

Palmitoyl Dipeptide-7

Palmitoyl Hexapeptide-12

Palmitoyl Tripeptide-1

Palmitoyl Tripeptide-5

Palmitoyl Pentapeptide-4

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Palmitoyl Tetrapeptide-7

Guaiazulene

Parfum

Water, Alcohol Denat., Methylpropanediol, 1,2-Hexanediol, Betaine, Dipropylene Glycol, Gardenia Taitensis Callus Extract, Oak Root Extract, Tremella Fuciformis Extract, Centella Asiatica Extract, Ficus Carica Fruit Extract, Orchid Leaf/Root/Stem Extract, Chamomilla Recutita Extract, Chrysanthemum Parthenium Extract, Hydrogenated Lecithin, Sodium Hyaluronate, Panthenol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glycerin, Tromethamine, Butylene Glycol, Polyglyceryl-10 Laurate, Dextrin, Sodium Phytate, Ceramide NP, Tocopherol, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Oligopeptide-6, Tripeptide-1, Copper Tripeptide-1, Hexapeptide-2, Dipeptide-2, Acetyl Tetrapeptide-3, Acetyl Tripeptide-1, Hexapeptide-9, Tripeptide-2, Nonapeptide-1, Pentapeptide-3, Tripeptide-3, Alanine/Histidine/Lysine Polypeptide Copper Hcl, Dipeptide-4, Acetyl Tetrapeptide-5, Palmitoyl Dipeptide-7, Palmitoyl Hexapeptide-12, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Pentapeptide-4, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tetrapeptide-7, Guaiazulene, Parfum, Ethylhexylglycerin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydrogenated Lecithin is a more stable version of lecithin.

It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.

This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.

Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.

A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).

Polyglyceryl-10 Laurate is a cleansing agent and emulsifier.

It rounds up dirt, oil, and grime, so they can be rinsed off easily as a cleanser.

On the emulsifier side, it keeps your formula smooth and well-mixed by playing peacekeeper for ingredients that don't naturally get along (like oil and water).

Because it has a C12 (lauric acid) fatty acid chain, this ingredient can potentially feed the Malassezia yeast that causes fungal acne. The Malassezia yeast prefers esters with C11-C24 fatty acids.

This ingredient is an ester of lauric acid and Polyglycerin-10.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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