Skin science article
MEDI-PEEL Peptide-Tox Bor Toner Versus MEDI-PEEL Hyal Kombucha Tea-Tox Toner
MEDI-PEEL Peptide-Tox Bor Toner Versus MEDI-PEEL Hyal Kombucha Tea-Tox Toner This anti-aging toner is formulated around Anemarrhena Asphodeloides Root Extract and Copper Tripeptide-1 to soften the look of wrinkles. This hydrating toner is formulated around Sac
MEDI-PEEL Peptide-Tox Bor Toner Versus MEDI-PEEL Hyal Kombucha Tea-Tox Toner
This anti-aging toner is formulated around Anemarrhena Asphodeloides Root Extract and Copper Tripeptide-1 to soften the look of wrinkles.
This hydrating toner is formulated around Saccharomyces/Xylinum/Black Tea Ferment and Niacinamide to hydrate skin and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Dipropylene Glycol
Methylpropanediol
Glycerin
1,2-Hexanediol
Butylene Glycol
Propanediol
Polyglyceryl-10 Laurate
Polyglyceryl-4 Laurate
Betaine
Allantoin
Carbomer
Trehalose
Panthenol
Leontopodium Alpinum Callus Culture Extract
Saccharomyces/Rice Ferment Filtrate
Lactobacillus Ferment
Lactobacillus/Pear Juice Ferment Filtrate
Lactobacillus/Punica Granatum Fruit Ferment Extract
Lactobacillus/Soybean Ferment Extract
Saccharomyces/Barley Seed Ferment Filtrate
Lactococcus Ferment
Chondrus Crispus Extract
Jania Rubens Extract
Anemarrhena Asphodeloides Root Extract
Melia Azadirachta Flower Extract
Ocimum Sanctum Leaf Extract
Melia Azadirachta Leaf Extract
Curcuma Longa Root Extract
Corallina Officinalis Extract
Hydrolyzed Collagen
Hydrolyzed Elastin
Sodium Hyaluronate
Glyceryl Acrylate/Acrylic Acid Copolymer
Dipotassium Glycyrrhizate
Arginine
Xanthan Gum
Gluconolactone
Hydrogenated Polyisobutene
Adenosine
Caprylyl/Capryl Glucoside
Tocopherol
Copper Tripeptide-1
Acetyl Hexapeptide-8
Palmitoyl Pentapeptide-4
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-1
Ethylhexylglycerin
Disodium EDTA
Parfum
Water, Dipropylene Glycol, Methylpropanediol, Glycerin, 1,2-Hexanediol, Butylene Glycol, Propanediol, Polyglyceryl-10 Laurate, Polyglyceryl-4 Laurate, Betaine, Allantoin, Carbomer, Trehalose, Panthenol, Leontopodium Alpinum Callus Culture Extract, Saccharomyces/Rice Ferment Filtrate, Lactobacillus Ferment, Lactobacillus/Pear Juice Ferment Filtrate, Lactobacillus/Punica Granatum Fruit Ferment Extract, Lactobacillus/Soybean Ferment Extract, Saccharomyces/Barley Seed Ferment Filtrate, Lactococcus Ferment, Chondrus Crispus Extract, Jania Rubens Extract, Anemarrhena Asphodeloides Root Extract, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Melia Azadirachta Leaf Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Hydrolyzed Collagen, Hydrolyzed Elastin, Sodium Hyaluronate, Glyceryl Acrylate/Acrylic Acid Copolymer, Dipotassium Glycyrrhizate, Arginine, Xanthan Gum, Gluconolactone, Hydrogenated Polyisobutene, Adenosine, Caprylyl/Capryl Glucoside, Tocopherol, Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Ethylhexylglycerin, Disodium EDTA, Parfum
Saccharomyces/Xylinum/Black Tea Ferment 70%
Cetyl Ethylhexanoate
Hydrogenated Poly(C6-14 Olefin)
Niacinamide
Caprylic/Capric Triglyceride
Decyl Glucoside
Saccharomyces/Rice Bran Ferment
Adansonia Digitata Seed Oil
Hydrogenated Lecithin
Camellia Sinensis Flower Extract
Citrus Unshiu Peel Extract
Madecassoside
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
Ceramide NP
Ceramide Ns
Ceramide As
Ceramide EOP
Ceramide AP
Hydrolyzed Glycosaminoglycans
Sodium Hyaluronate Crosspolymer
Hydrolyzed Hyaluronic Acid
Hydroxypropyltrimonium Hyaluronate
Hyaluronic Acid
Sodium Acetylated Hyaluronate
Rosa Damascena Flower Water
Pyrus Communis Fruit Extract
Prunus Persica Fruit Extract
Jasminum Officinale Flower Water
Hedera Helix Leaf/Stem Extract
Cucumis Melo Fruit Extract
Tocopheryl Acetate
Cyanocobalamin
Caprylyl Glycol
Magnesium Chloride
Benzyl Glycol
Polysorbate 60
Caramel
Pentylene Glycol
Saccharomyces/Xylinum/Black Tea Ferment 70%, Water, Cetyl Ethylhexanoate, Hydrogenated Poly(C6-14 Olefin), 1,2-Hexanediol, Niacinamide, Propanediol, Glycerin, Butylene Glycol, Caprylic/Capric Triglyceride, Decyl Glucoside, Carbomer, Saccharomyces/Rice Bran Ferment, Adansonia Digitata Seed Oil, Hydrogenated Lecithin, Camellia Sinensis Flower Extract, Citrus Unshiu Peel Extract, Madecassoside, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Ceramide NP, Ceramide Ns, Ceramide As, Ceramide EOP, Ceramide AP, Sodium Hyaluronate, Hydrolyzed Glycosaminoglycans, Sodium Hyaluronate Crosspolymer, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Hyaluronic Acid, Sodium Acetylated Hyaluronate, Rosa Damascena Flower Water, Pyrus Communis Fruit Extract, Prunus Persica Fruit Extract, Jasminum Officinale Flower Water, Hedera Helix Leaf/Stem Extract, Cucumis Melo Fruit Extract, Tocopheryl Acetate, Cyanocobalamin, Caprylyl Glycol, Magnesium Chloride, Benzyl Glycol, Polysorbate 60, Ethylhexylglycerin, Adenosine, Caramel, Pentylene Glycol
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!