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Skin science article

Medik8 Oxy-R Peptides Versus Medik8 Clarity Peptides

Medik8 Oxy-R Peptides Versus Medik8 Clarity Peptides This brightening serum is formulated around Gluconolactone to fade the look of dark spots and brighten dull-looking skin. This brightening serum is formulated around Niacinamide and Zinc PCA to brighten dull

Medik8 Oxy-R Peptides Versus Medik8 Clarity Peptides

This brightening serum is formulated around Gluconolactone to fade the look of dark spots and brighten dull-looking skin.

This brightening serum is formulated around Niacinamide and Zinc PCA to brighten dull-looking skin and refine the look of pores.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Artocarpus Lakoocha Wood Extract

Gluconolactone

Acetyl Glycyl Beta-Alanine

Glycerin

Lactic Acid

Sodium Benzoate

Disodium EDTA

Sodium Hyaluronate

Xanthan Gum

Calcium Gluconate

Sodium Metabisulfite

Tetrapeptide-30

Hydroxyresveratrol

Water, Butylene Glycol, Artocarpus Lakoocha Wood Extract, Gluconolactone, Acetyl Glycyl Beta-Alanine, Glycerin, Lactic Acid, Sodium Benzoate, Disodium EDTA, Sodium Hyaluronate, Xanthan Gum, Calcium Gluconate, Sodium Metabisulfite, Tetrapeptide-30, Hydroxyresveratrol

Niacinamide

Caprylic/Capric Triglyceride

Acetyl Glucosamine

Glyceryl Stearate Citrate

Dimethicone

Zinc PCA

Polyglyceryl-3 Stearate

Crambe Abyssinica Seed Oil

Hydroxyacetophenone

Hydrogenated Lecithin

Behenyl Alcohol

Cetearyl Alcohol

Phenoxyethanol

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Cetyl Palmitate

Carnosine

Ethylhexylglycerin

Polysorbate 80

Palmitoyl Tetrapeptide-10

Sorbitan Stearate

Polysorbate 60

Sorbitan Isostearate

Citric Acid

Tocopherol

1,2-Hexanediol

Caprylhydroxamic Acid

Water, Niacinamide, Caprylic/Capric Triglyceride, Acetyl Glucosamine, Glyceryl Stearate Citrate, Dimethicone, Zinc PCA, Glycerin, Polyglyceryl-3 Stearate, Crambe Abyssinica Seed Oil, Hydroxyacetophenone, Hydrogenated Lecithin, Behenyl Alcohol, Cetearyl Alcohol, Phenoxyethanol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Disodium EDTA, Xanthan Gum, Cetyl Palmitate, Carnosine, Ethylhexylglycerin, Polysorbate 80, Palmitoyl Tetrapeptide-10, Sorbitan Stearate, Sodium Hyaluronate, Polysorbate 60, Sorbitan Isostearate, Sodium Benzoate, Citric Acid, Tocopherol, Butylene Glycol, 1,2-Hexanediol, Caprylhydroxamic Acid

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  4. 04Topically, glycerin does several things at once:
  5. 05Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  6. 06Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  7. 07This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  8. 08Just know very high concentrations (>40%) can feel tacky in low humidity.
  9. 09Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  10. 10Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
  11. 11Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
  12. 12Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
  13. 13It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
  14. 14Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
  15. 15We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
  16. 16Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
  17. 17In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
  18. 18Interestingly, the size of the molecule affects its behavior:
  19. 19Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
  20. 20Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
Source · skinsort.com
02

Product index

Related product references

Product

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Medik8 Oxy-R Peptides

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03

Comparison edit

Read side by side