Mizon Peptide Ampoule Cream Versus IT Cosmetics Confidence in Your Beauty Sleep Night Cream

Mizon Peptide Ampoule Cream Versus IT Cosmetics Confidence in Your Beauty Sleep Night Cream

This anti-aging ampoule is formulated around Copper Tripeptide-1 and Adenosine to soften the look of wrinkles and strengthen the skin barrier.

This anti-aging night moisturizer is formulated around Simmondsia Chinensis Seed Oil and Adenosine to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Stearic Acid

Neopentyl Glycol Diheptanoate

Cetearyl Olivate

Sorbitan Olivate

Hydrogenated Poly(C6-14 Olefin)

Glycerin

Cyclomethicone

Butylene Glycol

Copper Tripeptide-1

Glyceryl Stearate

PEG-100 Stearate

Polyacrylate-13

Polyisobutene

Polysorbate 20

Cetearyl Alcohol

Cetearyl Glucoside

Dimethicone

Trehalose

Theobroma Cacao Extract

Caprylyl Glycol

Ethylhexylglycerin

Tropolone

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Triethanolamine

Coptis Japonica Extract

Adenosine

Propylene Glycol

Hydrolyzed Extensin

Rubus Idaeus Fruit Extract

Beta-Glucan

Biosaccharide Gum-1

Iris Florentina Root Extract

Hydrolyzed Wheat Protein

Prunus Amygdalus Dulcis Seed Extract

Lavandula Angustifolia Oil

Disodium EDTA

Water, Stearic Acid, Neopentyl Glycol Diheptanoate, Cetearyl Olivate, Sorbitan Olivate, Hydrogenated Poly(C6-14 Olefin), Glycerin, Cyclomethicone, Butylene Glycol, Copper Tripeptide-1, Glyceryl Stearate, PEG-100 Stearate, Polyacrylate-13, Polyisobutene, Polysorbate 20, Cetearyl Alcohol, Cetearyl Glucoside, Dimethicone, Trehalose, Theobroma Cacao Extract, Caprylyl Glycol, Ethylhexylglycerin, Tropolone, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Triethanolamine, Coptis Japonica Extract, Adenosine, Propylene Glycol, Hydrolyzed Extensin, Rubus Idaeus Fruit Extract, Beta-Glucan, Biosaccharide Gum-1, Iris Florentina Root Extract, Hydrolyzed Wheat Protein, Prunus Amygdalus Dulcis Seed Extract, Lavandula Angustifolia Oil, Disodium EDTA

Simmondsia Chinensis Seed Oil

Hydrogenated Castor Oil Dimer Dilinoleate

Propanediol

Alcohol Denat.

Caprylic/Capric Triglyceride

Cetyl Alcohol

Cetyl Hydroxyethylcellulose

Octyldodecanol

Silica

Phenoxyethanol

Albizia Julibrissin Bark Extract

Parfum

Poloxamer 338

Capryloyl Salicylic Acid

Limonene

Tocopherol

Xanthan Gum

Linalool

Ceramide NP

Hydroxypalmitoyl Sphinganine

Silica Dimethyl Silylate

Hydrated Silica

Sodium Hyaluronate

Polysorbate 60

Citronellol

Sodium Benzoate

CI 16035

Geraniol

Cereus Grandiflorus Flower Extract

Opuntia Ficus-Indica Flower Extract

Citral

Darutoside

CI 42090

Glucose

Lactic Acid

Potassium Sorbate

Water, Dimethicone, Glycerin, Simmondsia Chinensis Seed Oil, Hydrogenated Castor Oil Dimer Dilinoleate, Propanediol, Alcohol Denat., Caprylic/Capric Triglyceride, Cetyl Alcohol, Cetyl Hydroxyethylcellulose, Octyldodecanol, Silica, Phenoxyethanol, Albizia Julibrissin Bark Extract, Caprylyl Glycol, Parfum, Poloxamer 338, Capryloyl Salicylic Acid, Limonene, Adenosine, Tocopherol, Xanthan Gum, Disodium EDTA, Linalool, Ceramide NP, Hydroxypalmitoyl Sphinganine, Silica Dimethyl Silylate, Hydrated Silica, Sodium Hyaluronate, Polysorbate 60, Citronellol, Sodium Benzoate, CI 16035, Geraniol, Cereus Grandiflorus Flower Extract, Opuntia Ficus-Indica Flower Extract, Citral, Darutoside, CI 42090, Glucose, Lactic Acid, Potassium Sorbate

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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