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Mizon Peptide Ampoule Cream Versus Pyunkang Yul Intensive Repair Cream

Mizon Peptide Ampoule Cream Versus Pyunkang Yul Intensive Repair Cream This anti-aging ampoule is formulated around Copper Tripeptide-1 and Adenosine to soften the look of wrinkles and strengthen the skin barrier. This barrier-repair moisturizer is formulated

Mizon Peptide Ampoule Cream Versus Pyunkang Yul Intensive Repair Cream

This anti-aging ampoule is formulated around Copper Tripeptide-1 and Adenosine to soften the look of wrinkles and strengthen the skin barrier.

This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Ceramide NP to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Stearic Acid

Neopentyl Glycol Diheptanoate

Cetearyl Olivate

Sorbitan Olivate

Hydrogenated Poly(C6-14 Olefin)

Glycerin

Cyclomethicone

Butylene Glycol

Copper Tripeptide-1

Glyceryl Stearate

PEG-100 Stearate

Polyacrylate-13

Polyisobutene

Polysorbate 20

Cetearyl Alcohol

Cetearyl Glucoside

Dimethicone

Trehalose

Theobroma Cacao Extract

Caprylyl Glycol

Ethylhexylglycerin

Tropolone

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Triethanolamine

Coptis Japonica Extract

Adenosine

Propylene Glycol

Hydrolyzed Extensin

Rubus Idaeus Fruit Extract

Beta-Glucan

Biosaccharide Gum-1

Iris Florentina Root Extract

Hydrolyzed Wheat Protein

Prunus Amygdalus Dulcis Seed Extract

Lavandula Angustifolia Oil

Disodium EDTA

Water, Stearic Acid, Neopentyl Glycol Diheptanoate, Cetearyl Olivate, Sorbitan Olivate, Hydrogenated Poly(C6-14 Olefin), Glycerin, Cyclomethicone, Butylene Glycol, Copper Tripeptide-1, Glyceryl Stearate, PEG-100 Stearate, Polyacrylate-13, Polyisobutene, Polysorbate 20, Cetearyl Alcohol, Cetearyl Glucoside, Dimethicone, Trehalose, Theobroma Cacao Extract, Caprylyl Glycol, Ethylhexylglycerin, Tropolone, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Triethanolamine, Coptis Japonica Extract, Adenosine, Propylene Glycol, Hydrolyzed Extensin, Rubus Idaeus Fruit Extract, Beta-Glucan, Biosaccharide Gum-1, Iris Florentina Root Extract, Hydrolyzed Wheat Protein, Prunus Amygdalus Dulcis Seed Extract, Lavandula Angustifolia Oil, Disodium EDTA

Methylpropanediol

Caprylic/Capric Triglyceride

Macadamia Ternifolia Seed Oil

Hydrogenated Polydecene

Butyrospermum Parkii Butter

Arachidyl Alcohol

Behenyl Alcohol

Arachidyl Glucoside

Phenyl Trimethicone

Beeswax

Sorbitan Stearate

Cellulose Gum

Ceramide NP

Paeonia Lactiflora Bark/Sap Extract

Parfum

Cornus Officinalis Fruit Extract

Curcuma Longa Root Extract

Yeast Beta-Glucan

Aloe Barbadensis Leaf Powder

Hydrogenated Lecithin

Octyldodecanol

Carbomer

Hydroxyacetophenone

Myrtus Communis Extract

Tropaeolum Majus Extract

Tromethamine

Water, Glycerin, Methylpropanediol, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Macadamia Ternifolia Seed Oil, Hydrogenated Polydecene, Butyrospermum Parkii Butter, Glyceryl Stearate, Arachidyl Alcohol, Behenyl Alcohol, Arachidyl Glucoside, Phenyl Trimethicone, Cetearyl Glucoside, Beeswax, Sorbitan Stearate, Cellulose Gum, Ceramide NP, Paeonia Lactiflora Bark/Sap Extract, Parfum, Cornus Officinalis Fruit Extract, Curcuma Longa Root Extract, Yeast Beta-Glucan, Copper Tripeptide-1, Butylene Glycol, Aloe Barbadensis Leaf Powder, Hydrogenated Lecithin, Octyldodecanol, Carbomer, Hydroxyacetophenone, Myrtus Communis Extract, Tropaeolum Majus Extract, Tromethamine, Disodium EDTA, Ethylhexylglycerin

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.

Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.

Cetearyl Glucoside is a sugar-based emulsifier. It is usually made by combining cetearyl alcohol and glucose.

Belonging to the aklyl polyglucoside (APG) family, Cetearyl Glucoside has a sugar "head" that loves water and a fatty "tail" that loves oil. This means it can shuffle oil and water into a stable and smooth emulsion.

Typical use levels are between 1-5% and this ingredient is considered to be non-irritating by the CIR Expert Panel Review.

Once applied, your skin's glucoside hydrolases breaks it down to the parent fatty alcohol and glucose. This is why this ingredient may not be fungal acne safe.

Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.

It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.

While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.

Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.

Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.

Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.

For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.

After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.

While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.

Read more about other common types of peptides here:

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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The reference edit

Ingredients, questions
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Product index

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Comparison edit

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