Mizon S-Venom Wrinkle Tox Cream Versus Hydropeptide Power Lift

Mizon S-Venom Wrinkle Tox Cream Versus Hydropeptide Power Lift

This anti-aging moisturizer is formulated around Adenosine and Dipeptide Diaminobutyroyl Benzylamide Diacetate to soften the look of wrinkles.

This anti-aging moisturizer is formulated around Butyrospermum Parkii Butter and Dipeptide Diaminobutyroyl Benzylamide Diacetate to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Butylene Glycol

Cyclopentasiloxane

Butyrospermum Parkii Butter

Octyldodecyl Myristate

Caprylic/Capric Triglyceride

Hydrogenated Poly(C6-14 Olefin)

Glyceryl Stearate

Cetearyl Alcohol

Polysorbate 20

1,2-Hexanediol

Olea Europaea Fruit Oil

Helianthus Annuus Seed Oil

Cetearyl Olivate

Cyclohexasiloxane

Sorbitan Olivate

PEG-100 Stearate

Mangifera Indica Seed Butter

Dimethicone/Vinyl Dimethicone Crosspolymer

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Tromethamine

Limnanthes Alba Seed Oil

Ethylhexylglycerin

Adenosine

Parfum

Disodium EDTA

Sodium Ascorbyl Phosphate

Allantoin

Tocopheryl Acetate

Panthenol

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Sodium Hyaluronate

Beta-Glucan

Phenoxyethanol

Tocopherol

Copper Tripeptide-1

Tbhq

Palmitoyl Tripeptide-5

Water, Glycerin, Butylene Glycol, Cyclopentasiloxane, Butyrospermum Parkii Butter, Octyldodecyl Myristate, Caprylic/Capric Triglyceride, Hydrogenated Poly(C6-14 Olefin), Glyceryl Stearate, Cetearyl Alcohol, Polysorbate 20, 1,2-Hexanediol, Olea Europaea Fruit Oil, Helianthus Annuus Seed Oil, Cetearyl Olivate, Cyclohexasiloxane, Sorbitan Olivate, PEG-100 Stearate, Mangifera Indica Seed Butter, Dimethicone/Vinyl Dimethicone Crosspolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Limnanthes Alba Seed Oil, Ethylhexylglycerin, Adenosine, Parfum, Disodium EDTA, Sodium Ascorbyl Phosphate, Allantoin, Tocopheryl Acetate, Panthenol, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Sodium Hyaluronate, Beta-Glucan, Phenoxyethanol, Tocopherol, Copper Tripeptide-1, Tbhq, Palmitoyl Tripeptide-5

Silybum Marianum Ethyl Ester

Echinacea Purpurea Extract

Behenyl Alcohol

Isononyl Isononanoate

Arachidyl Alcohol

Ethylhexyl Isononanoate

Oryza Sativa Bran

Leuconostoc/Radish Root Ferment Filtrate

Tetrahydroxypropyl Ethylenediamine

Caprylyl Glycol

Arachidyl Glucoside

Menthoxypropanediol

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Xanthan Gum

Cetearyl Glucoside

Sorbitan Laurate

Squalane

Cyclodextrin

Tetrahexyldecyl Ascorbate

Buddleja Davidii Extract

O-Cymen-5-Ol

Polysorbate 60

Ananas Sativus Fruit Extract

Hydroxyethylcellulose

Acetyl Dipeptide-1 Cetyl Ester

Sodium Benzoate

Citric Acid

Potassium Sorbate

Glycyrrhiza Glabra Root Extract

Pyridoxine Tris-Hexyldecanoate

Arbutin

Magnesium Ascorbyl Phosphate

Tropolone

Myristoyl Tripeptide-31

Sodium Metabisulfite

Hexapeptide-10

Diacetyl Boldine

Triethyl Citrate

Lavandula Angustifolia Flower/Leaf/Stem Extract

Citrus Aurantium Bergamia Fruit Oil

Camellia Sinensis Leaf Extract

Salvia Officinalis Oil

Cupressus Sempervirens Oil

Rosmarinus Officinalis Leaf Oil

Coriandrum Sativum Fruit Oil

Salvia Sclarea Oil

Fucus Vesiculosus Extract

Jasminum Officinale Flower/Leaf Extract

Rosa Damascena Flower Extract

Vanilla Planifolia Fruit Extract

Rosmarinus Officinalis Leaf Extract

Water, Butylene Glycol, Silybum Marianum Ethyl Ester, Glycerin, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Echinacea Purpurea Extract, Behenyl Alcohol, Butyrospermum Parkii Butter, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Isononyl Isononanoate, Arachidyl Alcohol, Ethylhexyl Isononanoate, Oryza Sativa Bran, Leuconostoc/Radish Root Ferment Filtrate, Panthenol, Tetrahydroxypropyl Ethylenediamine, Caprylyl Glycol, 1,2-Hexanediol, Arachidyl Glucoside, Menthoxypropanediol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopheryl Acetate, Xanthan Gum, Cetearyl Glucoside, Sorbitan Laurate, Squalane, Cyclodextrin, Tetrahexyldecyl Ascorbate, Buddleja Davidii Extract, Disodium EDTA, O-Cymen-5-Ol, Sodium Hyaluronate, Polysorbate 60, Ananas Sativus Fruit Extract, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Sodium Benzoate, Citric Acid, Potassium Sorbate, Glycyrrhiza Glabra Root Extract, Pyridoxine Tris-Hexyldecanoate, Arbutin, Magnesium Ascorbyl Phosphate, Tropolone, Myristoyl Tripeptide-31, Sodium Metabisulfite, Hexapeptide-10, Diacetyl Boldine, Triethyl Citrate, Lavandula Angustifolia Flower/Leaf/Stem Extract, Citrus Aurantium Bergamia Fruit Oil, Camellia Sinensis Leaf Extract, Salvia Officinalis Oil, Cupressus Sempervirens Oil, Rosmarinus Officinalis Leaf Oil, Coriandrum Sativum Fruit Oil, Salvia Sclarea Oil, Fucus Vesiculosus Extract, Jasminum Officinale Flower/Leaf Extract, Rosa Damascena Flower Extract, Vanilla Planifolia Fruit Extract, Rosmarinus Officinalis Leaf Extract

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.

As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.

It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.

A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.

Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).

In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).

Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.

Shea butter also contains vitamins A and E which may contribute to antioxidant activity.

While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.

This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.

Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.

This small molecule peptide has similar benefits to Argireline, the "botox" peptide.

According to the manufacturer, this peptide mimics snake venom to freeze muscles. This prevents muscle movement and contractions to prohibit the formation of fine lines and wrinkles.

While this seems promising, research is lacking in proving this ingredient to be as effective as botox.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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