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Nacomi Next Level Spotless Skin Niacinamide 20% Versus Paula's Choice Clinical Niacinamide 20% Treatment

Nacomi Next Level Spotless Skin Niacinamide 20% Versus Paula's Choice Clinical Niacinamide 20% Treatment This brightening treatment is formulated around Niacinamide and Ascorbyl Glucoside to fade the look of dark spots and balance excess oil. This pore-care tr

Nacomi Next Level Spotless Skin Niacinamide 20% Versus Paula's Choice Clinical Niacinamide 20% Treatment

This brightening treatment is formulated around Niacinamide and Ascorbyl Glucoside to fade the look of dark spots and balance excess oil.

This pore-care treatment is formulated around Niacinamide and Acetyl Glucosamine to refine the look of pores and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Niacinamide

Glycerin

Ascorbyl Glucoside

Sodium Citrate

Potassium Azeloyl Diglycinate

Alpha-Arbutin

Trehalose

Sodium Hydroxypropyl Starch Phosphate

Hydrolyzed Yeast Extract

Hydrolyzed Glycosaminoglycans

Sodium Hyaluronate

Hyaluronic Acid

Hydrolyzed Hyaluronic Acid

Sodium Hyaluronate Crosspolymer

Polyglucuronic Acid

Lecithin

Cetyl Hydroxyethylcellulose

Dehydroacetic Acid

Xanthan Gum

Cellulose

Hectorite

Propanediol

Potassium Sorbate

Sodium Benzoate

Ethylhexylglycerin

Raspberry Ketone

Benzyl Glycol

Benzyl Alcohol

Water, Niacinamide, Glycerin, Ascorbyl Glucoside, Sodium Citrate, Potassium Azeloyl Diglycinate, Alpha-Arbutin, Trehalose, Sodium Hydroxypropyl Starch Phosphate, Hydrolyzed Yeast Extract, Hydrolyzed Glycosaminoglycans, Sodium Hyaluronate, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Polyglucuronic Acid, Lecithin, Cetyl Hydroxyethylcellulose, Dehydroacetic Acid, Xanthan Gum, Cellulose, Hectorite, Propanediol, Potassium Sorbate, Sodium Benzoate, Ethylhexylglycerin, Raspberry Ketone, Benzyl Glycol, Benzyl Alcohol

Niacinamide 20%

Pentylene Glycol

Butylene Glycol

Acetyl Glucosamine

Glycyrrhiza Glabra Root Extract

Spiraea Ulmaria Extract

Portulaca Oleracea Extract

Camellia Japonica Flower Extract

Epigallocatechin Gallate

Boerhavia Diffusa Root Extract

Camellia Sinensis Leaf Extract

Allantoin

Pullulan

Panthenol

Silica

Sclerotium Gum

Sodium Phytate

Phenoxyethanol

Water, Niacinamide 20%, Pentylene Glycol, Butylene Glycol, Glycerin, Acetyl Glucosamine, Ascorbyl Glucoside, Glycyrrhiza Glabra Root Extract, Spiraea Ulmaria Extract, Portulaca Oleracea Extract, Camellia Japonica Flower Extract, Epigallocatechin Gallate, Boerhavia Diffusa Root Extract, Camellia Sinensis Leaf Extract, Allantoin, Lecithin, Pullulan, Panthenol, Silica, Xanthan Gum, Sclerotium Gum, Propanediol, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Ascorbyl Glucoside (AA-2G) is one of the most stable vitamin C derivatives out there.

It's made by attaching a glucose molecule to ascorbic acid; this glucose "cap" shields the vitamin C from air, light, heat, and metal ions that normally cause pure ascorbic acid to oxidize.

Once on your skin, the enzyme alpha-glucosidase snips off the glucose and gradually releases active ascorbic acid right where it's needed. Basically, it behaves like a slow-release pro-vitamin C with less of a stinging that high-strength ascorbic acid can cause.

The research supports the classic vitamin C benefits as well. In lab and human studies, AA-2G slowed down the skin's production of melanin (the pigment behind dark spots) and helped shield skin cells against sun damage better than ascorbyl phosphate.

These studies also showed AA-2G released vitamin C over a longer period.

A frequently cited manufacturer trial found that a 2% AA-2G face cream significantly improved wrinkle depth and skin roughness after 45 days.

And in 2009, a clinical trial showed it meaningfully lightened dark patches on the gums compared to a placebo.

There's also collagen-synthesis support (since vitamin C is a required cofactor for that) and an antioxidant effect too.

Typical usage is usually between 0.5-5% and most studies/products land around 2%.

AA-2G performs best when formulated at a mildly acidic pH (~5-7) which is much gentler than the pH that pure vitamin C demands (~2.5-3.5).

Just one thing worth knowing: the in-skin conversation rate is only about 55-60% by weight. So a 5% AA-2G product delivers roughly 2.75-3% of actual active vitamin C. On top of that, skin absorption is relatively low because the ingredient is water-soluble.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.

Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:

It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Butylene Glycol
  3. 03Polysorbate 20
  4. 04Glycerin
  5. 05Colloidal Oatmeal
  6. 06Beta-Glucan
  7. 07Sea Whip Extract
  8. 08Boerhavia Diffusa Root Extract
  9. 09Panthenol
  10. 10Epigallocatechin Gallate
  11. 11Gellan Gum
  12. 12Phytic Acid
  13. 13Disodium EDTA
  14. 14Ethylhexylglycerin
  15. 15Potassium Sorbate
  16. 16Water, Butylene Glycol, Polysorbate 20, Glycerin, Colloidal Oatmeal, Beta-Glucan, Sea Whip Extract, Boerhavia Diffusa Root Extract, Panthenol, Epigallocatechin Gallate, Gellan Gum, Phytic Acid, Disodium EDTA, Ethylhexylglycerin, Potassium Sorbate
  17. 17Propanediol
  18. 18Betaine
  19. 191,2-Hexanediol
  20. 20Polyglycerin-3
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side