Naturium Quadruple Hyaluronic Acid Serum 5% Versus Bliss Glow & Hydrate Day Serum

Naturium Quadruple Hyaluronic Acid Serum 5% Versus Bliss Glow & Hydrate Day Serum

This hydrating serum is formulated around Hydrolyzed Hyaluronic Acid and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.

This hydrating serum is formulated around Niacinamide and Sodium Hyaluronate to hydrate skin and brighten dull-looking skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Propanediol

Hydrolyzed Hyaluronic Acid

Sodium Hyaluronate

Apricot Kernel Oil Polyglyceryl-6 Esters

Polyglyceryl-6 Oleate

Caprylyl Glycol

Polyglyceryl-10 Oleate

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Magnolol

Kaempferol

Tetrahexyldecyl Ascorbate

Glycolipids

Glycine Soja Sterols

Tocopheryl Acetate

Phenoxyethanol

Sorbitan Palmate

Potassium Sorbate

Sodium Hydroxide

Glyceryl Polyacrylate

Xanthan Gum

Hexylene Glycol

Water, Glycerin, Propanediol, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Apricot Kernel Oil Polyglyceryl-6 Esters, Polyglyceryl-6 Oleate, Caprylyl Glycol, Polyglyceryl-10 Oleate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Magnolol, Kaempferol, Tetrahexyldecyl Ascorbate, Glycolipids, Glycine Soja Sterols, Tocopheryl Acetate, Phenoxyethanol, Sorbitan Palmate, Potassium Sorbate, Sodium Hydroxide, Glyceryl Polyacrylate, Xanthan Gum, Hexylene Glycol

Niacinamide

Aloe Barbadensis Leaf Juice

Coco-Caprylate/Caprate

Dimethicone

C15-19 Alkane

Tocopherol

Glycyrrhiza Glabra Root Extract

Glycine Soja Oil

Helianthus Annuus Seed Oil

Avena Sativa Kernel Oil

Acacia Senegal Gum

Cetearyl Olivate

Saccharide Isomerate

Shea Butter Ethyl Esters

Polyacrylate Crosspolymer-6

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Polyglyceryl-4 Laurate/Succinate

Sorbitan Olivate

Glyceryl Stearate

Lauryl Glucoside

Sodium Citrate

Ethylhexylglycerin

Sodium Benzoate

Citric Acid

Parfum

Water, Niacinamide, Glycerin, Propanediol, Aloe Barbadensis Leaf Juice, Coco-Caprylate/Caprate, Dimethicone, C15-19 Alkane, Sodium Hyaluronate, Tocopherol, Tocopheryl Acetate, Glycyrrhiza Glabra Root Extract, Glycine Soja Oil, Helianthus Annuus Seed Oil, Avena Sativa Kernel Oil, Xanthan Gum, Acacia Senegal Gum, Cetearyl Olivate, Saccharide Isomerate, Caprylyl Glycol, Shea Butter Ethyl Esters, Polyacrylate Crosspolymer-6, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polyglyceryl-4 Laurate/Succinate, Sorbitan Olivate, Glyceryl Stearate, Lauryl Glucoside, Hexylene Glycol, Sodium Citrate, Phenoxyethanol, Ethylhexylglycerin, Potassium Sorbate, Sodium Benzoate, Citric Acid, Sodium Hydroxide, Parfum

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hexylene Glycol is a multitasker ingredient that works as a solvent, humectant, emulsifier, viscosity reducer, and preservative booster.

It is able to dissolve both water and oil-soluble ingredients to stabilize tricky actives and make products spread more easily.

As a humectant, it pulls water into the skin. But it's a pretty minor moisturizing ingredient compared to other humectants, like glycerin.

Interestingly, it can act as a mild penetration enhancer. One in vitro study on human skin found a 12% concentration upped the absorption of mometasone furoate (a medicinal ingredient used to treat inflammatory skin conditions) up to 7%.

This ingredient is typically used at levels of 0.1-10% depending on the role it's playing.

A patch test study on eczema patients didn't find a significant increase in irritation versus the control group, but the potential for irritation rises at higher concentrations.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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