Skin science article
Nineless A-Control 10% Azelaic Acid Serum Versus APLB Azelaic Acid Peptide Ampoule Serum
Nineless A-Control 10% Azelaic Acid Serum Versus APLB Azelaic Acid Peptide Ampoule Serum This acne serum is formulated around Azelaic Acid and Niacinamide to clear breakouts and calm redness. This calming ampoule is formulated around Azelaic Acid and Sh-Oligop
Nineless A-Control 10% Azelaic Acid Serum Versus APLB Azelaic Acid Peptide Ampoule Serum
This acne serum is formulated around Azelaic Acid and Niacinamide to clear breakouts and calm redness.
This calming ampoule is formulated around Azelaic Acid and Sh-Oligopeptide-1 to calm redness and fade the look of dark spots.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Azelaic Acid
Dipropylene Glycol
Pentylene Glycol
Sodium Hydroxide
1,2-Hexanediol
Niacinamide
Panthenol
Snail Secretion Filtrate
Butylene Glycol
Ethylhexylglycerin
Propanediol
Hyaluronic Acid
Hydrolyzed Hyaluronic Acid
Sodium Hyaluronate
Water, Azelaic Acid, Dipropylene Glycol, Pentylene Glycol, Sodium Hydroxide, 1,2-Hexanediol, Niacinamide, Panthenol, Snail Secretion Filtrate, Butylene Glycol, Ethylhexylglycerin, Propanediol, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate
Centella Asiatica Leaf Water
Glycerin
Diethoxyethyl Succinate
Sh-Oligopeptide-1
Madecassic Acid
Asiaticoside
Asiatic Acid
Squalane
Solanum Melongena Fruit Extract
Melaleuca Alternifolia Leaf Extract
Beta-Glucan
Hippophae Rhamnoides Fruit Extract
Nelumbo Nucifera Extract
Artemisia Annua Extract
Oryza Sativa Extract
Saccharomyces Ferment
Sodium Citrate
Allantoin
Cellulose Gum
Disodium EDTA
Glyceryl Acrylate/Acrylic Acid Copolymer
Citric Acid
Xanthan Gum
Inulin
Cellulose
Glucose
Fructose
Hydroxyacetophenone
Sodium Polyacryloyldimethyl Taurate
Dipotassium Glycyrrhizate
Water, Centella Asiatica Leaf Water, Butylene Glycol, Propanediol, Glycerin, Diethoxyethyl Succinate, Azelaic Acid, Sh-Oligopeptide-1, Madecassic Acid, Asiaticoside, Asiatic Acid, Squalane, Solanum Melongena Fruit Extract, Melaleuca Alternifolia Leaf Extract, Beta-Glucan, Hippophae Rhamnoides Fruit Extract, Nelumbo Nucifera Extract, Artemisia Annua Extract, Oryza Sativa Extract, Saccharomyces Ferment, Dipropylene Glycol, Sodium Citrate, Sodium Hyaluronate, Allantoin, Cellulose Gum, Disodium EDTA, Glyceryl Acrylate/Acrylic Acid Copolymer, Citric Acid, Xanthan Gum, Inulin, Cellulose, Glucose, Fructose, Panthenol, Ethylhexylglycerin, Hydroxyacetophenone, Sodium Polyacryloyldimethyl Taurate, Dipotassium Glycyrrhizate, 1,2-Hexanediol
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.
What makes it special?
OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.
Here's what each tier does best:
Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.
Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.
This ingredient helps:
Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.
As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.
Studies show Dipropylene Glycol is considered safe to use in skincare.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!