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Obagi Elastiderm Eye Cream Versus SkinMedica TNS® Advanced+ Serum

Obagi Elastiderm Eye Cream Versus SkinMedica TNS® Advanced+ Serum What's inside Key Ingredients Benefits Concerns Ingredients Side-by-side Water C12-15 Alkyl Benzoate Ethylhexyl Palmitate C13-15 Alkane Cyclopentasiloxane Glycerin Glyceryl Stearate PEG-100 Stea

Obagi Elastiderm Eye Cream Versus SkinMedica TNS® Advanced+ Serum

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

C12-15 Alkyl Benzoate

Ethylhexyl Palmitate

C13-15 Alkane

Cyclopentasiloxane

Glycerin

Glyceryl Stearate

PEG-100 Stearate

Propylene Glycol

Stearyl Alcohol

Dipropylene Glycol Dibenzoate

Dimethicone

PPG-15 Stearyl Ether Benzoate

Polyacrylamide

Cetyl Alcohol

Cetyl Dimethicone

C13-14 Isoparaffin

Xanthan Gum

Magnesium Aluminum Silicate

Laureth-7

Tocopheryl Acetate

Glycyrrhiza Glabra Root Extract

Algae Extract

Vaccinium Angustifolium Fruit Extract

Phenoxyethanol

Methylparaben

Ethylparaben

Butylparaben

Propylparaben

Isobutylparaben

Hdi/Trimethylol Hexyllactone Crosspolymer

Sodium Hydroxide

Malonic Acid

Malachite

Zinc Carbonate

Silica

Talc

Alumina

Mica

CI 77891

CI 77491

CI 42090

Water, C12-15 Alkyl Benzoate, Ethylhexyl Palmitate, C13-15 Alkane, Cyclopentasiloxane, Glycerin, Glyceryl Stearate, PEG-100 Stearate, Propylene Glycol, Stearyl Alcohol, Dipropylene Glycol Dibenzoate, Dimethicone, PPG-15 Stearyl Ether Benzoate, Polyacrylamide, Cetyl Alcohol, Cetyl Dimethicone, C13-14 Isoparaffin, Xanthan Gum, Magnesium Aluminum Silicate, Laureth-7, Tocopheryl Acetate, Glycyrrhiza Glabra Root Extract, Algae Extract, Vaccinium Angustifolium Fruit Extract, Phenoxyethanol, Methylparaben, Ethylparaben, Butylparaben, Propylparaben, Isobutylparaben, Hdi/Trimethylol Hexyllactone Crosspolymer, Sodium Hydroxide, Malonic Acid, Malachite, Zinc Carbonate, Silica, Talc, Alumina, Mica, CI 77891, CI 77491, CI 42090

Pentylene Glycol

Human Neonatal Fibroblast Conditioned Media

Glycereth-7 Triacetate

Shea Butter Ethyl Esters

Ethoxydiglycol

Lactococcus Ferment Lysate

Whey Protein

Chlorella Vulgaris Extract

Saccharide Isomerate

Dimer Tripeptide-43

Vitis Vinifera Flower Cell Extract

Pyrus Malus Fruit Extract

Hydroxyacetophenone

Propanediol

Polyacrylate Crosspolymer-6

Polyacrylate-13

Polyisobutene

Sclerotium Gum

PEG-12 Dimethicone

Lecithin

Pullulan

Butylene Glycol

Sodium Citrate

Polysorbate 20

Aminomethyl Propanol

Disodium EDTA

Ethylhexylglycerin

Water, Pentylene Glycol, Human Neonatal Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Dimer Tripeptide-43, Vitis Vinifera Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  4. 04Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  5. 05Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  6. 06Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
  7. 07This ingredient mainly works behind the scenes and helps with:
  8. 08On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
  9. 09One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too st…
  10. 10Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
  11. 11You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
  12. 12Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
  13. 13The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure …
  14. 14Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
  15. 15Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  16. 16Topically, glycerin does several things at once:
  17. 17Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  18. 18Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  19. 19This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  20. 20Just know very high concentrations (>40%) can feel tacky in low humidity.
Source · skinsort.com
02

Product index

Related product references

Product

SkinMedica Tns Advanced+ Serum

SkinMedica Tns Advanced+ Serum SkinMedica Tns Advanced+ Serum ingredients explained: Water/Aqua/Eau, Pentylene Glycol, Human Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butte…

Source: incidecoder.comView reference →

Product

SkinMedica Tns Advanced+ Serum

SkinMedica Tns Advanced+ Serum SkinMedica Tns Advanced+ Serum ingredients explained: Aqua/Water/Eau, Pentylene Glycol, Human Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butte…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side