Skin science article
ongredients Skin Barrier Calming Lotion Versus COSRX The 6 Peptide Skin Booster Serum
ongredients Skin Barrier Calming Lotion Versus COSRX The 6 Peptide Skin Booster Serum This barrier-repair moisturizer is formulated around Centella Asiatica Extract and Copper Tripeptide-1 to strengthen the skin barrier and calm redness. This anti-aging serum
ongredients Skin Barrier Calming Lotion Versus COSRX The 6 Peptide Skin Booster Serum
This barrier-repair moisturizer is formulated around Centella Asiatica Extract and Copper Tripeptide-1 to strengthen the skin barrier and calm redness.
This anti-aging serum is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Propanediol
Caprylic/Capric Triglyceride
Cetyl Ethylhexanoate
1,2-Hexanediol
Glyceryl Stearate
Phenyl Trimethicone
C14-22 Alcohols
Polysorbate 60
Arginine
Coptis Japonica Root Extract
Carbomer
Butylene Glycol
Corchorus Olitorius Leaf Extract
Daucus Carota Sativa Root Extract
Ilex Paraguariensis Leaf Extract
Borago Officinalis Extract
C12-20 Alkyl Glucoside
Centella Asiatica Extract
Glucose
Polyglyceryl-10 Laurate
Ethylhexylglycerin
Tripeptide-1
Copper Tripeptide-1
Palmitoyl Pentapeptide-4
Palmitoyl Tripeptide-1
Hexapeptide-9
Hexapeptide-11
Acetyl Tetrapeptide-2
Acetyl Tetrapeptide-5
Palmitoyl Tripeptide-5
Water, Glycerin, Propanediol, Caprylic/Capric Triglyceride, Cetyl Ethylhexanoate, 1,2-Hexanediol, Glyceryl Stearate, Phenyl Trimethicone, C14-22 Alcohols, Polysorbate 60, Arginine, Coptis Japonica Root Extract, Carbomer, Butylene Glycol, Corchorus Olitorius Leaf Extract, Daucus Carota Sativa Root Extract, Ilex Paraguariensis Leaf Extract, Borago Officinalis Extract, C12-20 Alkyl Glucoside, Centella Asiatica Extract, Glucose, Polyglyceryl-10 Laurate, Ethylhexylglycerin, Tripeptide-1, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Hexapeptide-9, Hexapeptide-11, Acetyl Tetrapeptide-2, Acetyl Tetrapeptide-5, Palmitoyl Tripeptide-5
Dipropylene Glycol
Pentylene Glycol
Niacinamide
Acetyl Hexapeptide-8
Sh-Polypeptide-121
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Oligopeptide-68
Palmitoyl Tripeptide-8
Allantoin
Sodium Hyaluronate
Acetyl Glucosamine
Serine
Alanine
Glycine
Threonine
Proline
Betaine
Sodium PCA
Sodium Lactate
PCA
Glutamic Acid
Lysine Hcl
Tocopherol
Dextran
Glycine Soja Oil
Hydrogenated Lecithin
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Polyacrylate Crosspolymer-6
Xanthan Gum
Adenosine
Polyquaternium-51
Disodium EDTA
Citric Acid
Caprylyl Glycol
T-Butyl Alcohol
Potassium Sorbate
Sodium Oleate
Water, Dipropylene Glycol, Glycerin, Pentylene Glycol, 1,2-Hexanediol, Niacinamide, Acetyl Hexapeptide-8, Copper Tripeptide-1, Sh-Polypeptide-121, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Oligopeptide-68, Palmitoyl Tripeptide-8, Allantoin, Sodium Hyaluronate, Acetyl Glucosamine, Serine, Alanine, Glycine, Threonine, Arginine, Proline, Betaine, Sodium PCA, Sodium Lactate, PCA, Glutamic Acid, Lysine Hcl, Tocopherol, Dextran, Glycine Soja Oil, Hydrogenated Lecithin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Polyacrylate Crosspolymer-6, Butylene Glycol, Xanthan Gum, Ethylhexylglycerin, Adenosine, Polyquaternium-51, Disodium EDTA, Citric Acid, Caprylyl Glycol, T-Butyl Alcohol, Potassium Sorbate, Sodium Oleate
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.
It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.
While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.
Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.
Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.
Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.
For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.
After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.
While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.
Read more about other common types of peptides here:
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!