Oxecure Acne Defense Prebio Serum Versus COSRX The 6 Peptide Skin Booster Serum

Oxecure Acne Defense Prebio Serum Versus COSRX The 6 Peptide Skin Booster Serum

This acne serum is formulated around Inulin and Melaleuca Alternifolia Leaf Oil to clear breakouts and calm redness.

This anti-aging serum is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Polysorbate 20

Propanediol

Sclerotium Gum

Ceramide AP

1,2-Hexanediol

Caprylhydroxamic Acid

Croton Lechleri Resin Extract

Aloe Barbadensis Leaf Juice

Mannitol

Cellulose

Hydroxypropyl Methylcellulose

Inulin

Yeast Beta-Glucan

Undaria Pinnatifida Extract

Sodium Hyaluronate

PEG-40 Hydrogenated Castor Oil

Melaleuca Alternifolia Leaf Oil

Butylene Glycol

Dipotassium Glycyrrhizate

Lactobacillus/Rye Flour Ferment

Saccharide Isomerate

Xanthan Gum

Glucose

Chondrus Crispus Extract

Hydroxypropyltrimonium Hyaluronate

Hydrolyzed Hyaluronic Acid

Sodium Acetylated Hyaluronate

Hyaluronic Acid

Sodium Hyaluronate Crosspolymer

Hydrolyzed Sodium Hyaluronate

Potassium Hyaluronate

Caprylyl Glycol

Houttuynia Cordata Extract

Glycyrrhiza Glabra Root Extract

Scutellaria Baicalensis Root Extract

Pistacia Lentiscus Gum

Lecithin

Glycerin

Alcohol

Morus Alba Root Extract

Artemisia Capillaris Flower Extract

Zizyphus Jujuba Fruit Extract

Taraktogenos Kurzii Seed Oil

Nigella Sativa Seed Oil

Leptospermum Scoparium Branch/Leaf Oil

Potassium Lauroyl Wheat Amino Acids

Palm Glycerides

Capryloyl Glycine

Magnolia Grandiflora Bark Extract

Centella Asiatica Extract

Polygonum Cuspidatum Root Extract

Camellia Sinensis Leaf Extract

Chamomilla Recutita Flower Extract

Rosmarinus Officinalis Leaf Extract

Phenoxyethanol

Sodium Benzoate

Potassium Sorbate

Citric Acid

Sodium Citrate

Water, Polysorbate 20, Propanediol, Sclerotium Gum, Ceramide AP, 1,2-Hexanediol, Caprylhydroxamic Acid, Croton Lechleri Resin Extract, Aloe Barbadensis Leaf Juice, Mannitol, Cellulose, Hydroxypropyl Methylcellulose, Inulin, Yeast Beta-Glucan, Undaria Pinnatifida Extract, Sodium Hyaluronate, PEG-40 Hydrogenated Castor Oil, Melaleuca Alternifolia Leaf Oil, Butylene Glycol, Dipotassium Glycyrrhizate, Lactobacillus/Rye Flour Ferment, Saccharide Isomerate, Xanthan Gum, Glucose, Chondrus Crispus Extract, Hydroxypropyltrimonium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Caprylyl Glycol, Houttuynia Cordata Extract, Glycyrrhiza Glabra Root Extract, Scutellaria Baicalensis Root Extract, Pistacia Lentiscus Gum, Lecithin, Glycerin, Alcohol, Morus Alba Root Extract, Artemisia Capillaris Flower Extract, Zizyphus Jujuba Fruit Extract, Taraktogenos Kurzii Seed Oil, Nigella Sativa Seed Oil, Leptospermum Scoparium Branch/Leaf Oil, Potassium Lauroyl Wheat Amino Acids, Palm Glycerides, Capryloyl Glycine, Magnolia Grandiflora Bark Extract, Centella Asiatica Extract, Polygonum Cuspidatum Root Extract, Camellia Sinensis Leaf Extract, Chamomilla Recutita Flower Extract, Rosmarinus Officinalis Leaf Extract, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Citric Acid, Sodium Citrate

Dipropylene Glycol

Pentylene Glycol

Niacinamide

Acetyl Hexapeptide-8

Copper Tripeptide-1

Sh-Polypeptide-121

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Oligopeptide-68

Palmitoyl Tripeptide-8

Allantoin

Acetyl Glucosamine

Serine

Alanine

Glycine

Threonine

Arginine

Proline

Betaine

Sodium PCA

Sodium Lactate

PCA

Glutamic Acid

Lysine Hcl

Tocopherol

Dextran

Glycine Soja Oil

Hydrogenated Lecithin

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Polyacrylate Crosspolymer-6

Ethylhexylglycerin

Adenosine

Polyquaternium-51

Disodium EDTA

T-Butyl Alcohol

Sodium Oleate

Water, Dipropylene Glycol, Glycerin, Pentylene Glycol, 1,2-Hexanediol, Niacinamide, Acetyl Hexapeptide-8, Copper Tripeptide-1, Sh-Polypeptide-121, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Oligopeptide-68, Palmitoyl Tripeptide-8, Allantoin, Sodium Hyaluronate, Acetyl Glucosamine, Serine, Alanine, Glycine, Threonine, Arginine, Proline, Betaine, Sodium PCA, Sodium Lactate, PCA, Glutamic Acid, Lysine Hcl, Tocopherol, Dextran, Glycine Soja Oil, Hydrogenated Lecithin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Polyacrylate Crosspolymer-6, Butylene Glycol, Xanthan Gum, Ethylhexylglycerin, Adenosine, Polyquaternium-51, Disodium EDTA, Citric Acid, Caprylyl Glycol, T-Butyl Alcohol, Potassium Sorbate, Sodium Oleate

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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