Skin science article
Origins Plantscription Multi-Powered Youth Serum Versus RoC Retinol Correxion Deep Wrinkle Anti-Aging Facial Serum
Origins Plantscription Multi-Powered Youth Serum Versus RoC Retinol Correxion Deep Wrinkle Anti-Aging Facial Serum This anti-aging serum is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture. This anti
Origins Plantscription Multi-Powered Youth Serum Versus RoC Retinol Correxion Deep Wrinkle Anti-Aging Facial Serum
This anti-aging serum is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture.
This anti-aging serum is formulated around Retinol and Ascorbic Acid to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Butylene Glycol
Niacinamide
Glycerin
Heptyl Undecylenate
Octyldodecanol
Glycereth-26
Sodium Acrylates Copolymer
Algae Extract
Illicium Verum Fruit/Seed Oil
Citrus Aurantium Bergamia Fruit Oil
Pelargonium Graveolens Flower Oil
Lavandula Angustifolia Oil
Citrus Limon Peel Oil
Litsea Cubeba Fruit Oil
Citrus Nobilis Peel Oil
Myristica Fragrans Kernel Oil
Citrus Aurantium Dulcis Oil
Rosa Damascena Flower Oil
Hibiscus Abelmoschus Extract
Carthamus Tinctorius Seed Oil
Linalool
Geraniol
Citronellol
Limonene
Anogeissus Leiocarpus Bark Extract
Acetyl Hexapeptide-8
Palmitoyl Tripeptide-1
Acetyl Octapeptide-3
Palmitoyl Tetrapeptide-7
Palmitoyl Hexapeptide-12
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Sodium Hyaluronate
Sigesbeckia Orientalis Extract
Commiphora Mukul Resin Extract
Laminaria Saccharina Extract
Glucosamine Hcl
Bambusa Vulgaris Extract
Caffeine
Rosmarinus Officinalis Leaf Extract
Molasses Extract
Tocopheryl Acetate
Scutellaria Baicalensis Root Extract
Pyrus Malus Fruit Extract
Cucumis Sativus Fruit Extract
Pisum Sativum Extract
Caprylic/Capric Triglyceride
Lecithin
Xanthan Gum
Caprylyl Glycol
Hexylene Glycol
PEG-8
Glyceryl Polymethacrylate
Carbomer
Polysorbate 20
Sodium Metabisulfite
Sodium Sulfite
Disodium EDTA
Sodium Phytate
BHT
Potassium Sorbate
Phenoxyethanol
Water, Butylene Glycol, Niacinamide, Glycerin, Heptyl Undecylenate, Octyldodecanol, Glycereth-26, Sodium Acrylates Copolymer, Algae Extract, Illicium Verum Fruit/Seed Oil, Citrus Aurantium Bergamia Fruit Oil, Pelargonium Graveolens Flower Oil, Lavandula Angustifolia Oil, Citrus Limon Peel Oil, Litsea Cubeba Fruit Oil, Citrus Nobilis Peel Oil, Myristica Fragrans Kernel Oil, Citrus Aurantium Dulcis Oil, Rosa Damascena Flower Oil, Hibiscus Abelmoschus Extract, Carthamus Tinctorius Seed Oil, Linalool, Geraniol, Citronellol, Limonene, Anogeissus Leiocarpus Bark Extract, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Acetyl Octapeptide-3, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Sodium Hyaluronate, Sigesbeckia Orientalis Extract, Commiphora Mukul Resin Extract, Laminaria Saccharina Extract, Glucosamine Hcl, Bambusa Vulgaris Extract, Caffeine, Rosmarinus Officinalis Leaf Extract, Molasses Extract, Tocopheryl Acetate, Scutellaria Baicalensis Root Extract, Pyrus Malus Fruit Extract, Cucumis Sativus Fruit Extract, Pisum Sativum Extract, Caprylic/Capric Triglyceride, Lecithin, Xanthan Gum, Caprylyl Glycol, Hexylene Glycol, PEG-8, Glyceryl Polymethacrylate, Carbomer, Polysorbate 20, Sodium Metabisulfite, Sodium Sulfite, Disodium EDTA, Sodium Phytate, BHT, Potassium Sorbate, Phenoxyethanol
Cyclopentasiloxane
Tetrahydroxypropyl Ethylenediamine
Dimethicone Crosspolymer
Dimethicone
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Nylon-12
PEG-12 Dimethicone
Tocopherol
Citric Acid
Pentylene Glycol
Laureth-23
Hydrolyzed Wheat Protein
Parfum
Laureth-4
Methylparaben
Propylparaben
Alanine
Helianthus Annuus Seed Oil
C13-14 Isoparaffin
Magnesium Aspartate
Zinc Gluconate
Bisabolol
Retinol
Ascorbic Acid
Laureth-7
Copper Gluconate
CI 19140
Water, Cyclopentasiloxane, Glycerin, Tetrahydroxypropyl Ethylenediamine, Dimethicone Crosspolymer, Dimethicone, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Nylon-12, PEG-12 Dimethicone, Tocopherol, Phenoxyethanol, Citric Acid, Butylene Glycol, Pentylene Glycol, Laureth-23, Hydrolyzed Wheat Protein, Parfum, Laureth-4, Methylparaben, Propylparaben, Disodium EDTA, Alanine, BHT, Helianthus Annuus Seed Oil, C13-14 Isoparaffin, Polysorbate 20, Magnesium Aspartate, Zinc Gluconate, Bisabolol, Retinol, Ascorbic Acid, Laureth-7, Copper Gluconate, CI 19140
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
BHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.
It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.
The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.
Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).
True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.
Because it is derived from lauric acid, it may not be fungal acne safe.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!