Skin science article
Origins Super Spot Remover™ Acne Treatment Gel Versus Paula's Choice Regular Strength Daily Skin Clearing Treatment with 2.5% Benzoyl Peroxide
Origins Super Spot Remover™ Acne Treatment Gel Versus Paula's Choice Regular Strength Daily Skin Clearing Treatment with 2.5% Benzoyl Peroxide This acne treatment is formulated around Salicylic Acid to clear breakouts and refine the look of pores. This acne tr
Origins Super Spot Remover™ Acne Treatment Gel Versus Paula's Choice Regular Strength Daily Skin Clearing Treatment with 2.5% Benzoyl Peroxide
This acne treatment is formulated around Salicylic Acid to clear breakouts and refine the look of pores.
This acne treatment is formulated around Benzoyl Peroxide and Bisabolol to clear breakouts and calm redness.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Alcohol Denat.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Salicylic Acid
Hamamelis Virginiana Water
Eugenia Caryophyllus Bud Oil
Origanum Heracleoticum Flower Oil
Eugenol
Limonene
Cucumis Sativus Fruit Extract
Pyrus Malus Fruit Extract
Scutellaria Baicalensis Root Extract
Algae Extract
Poria Cocos Sclerotium Extract
Laminaria Saccharina Extract
Lactobacillus Ferment
Glycerin
Caffeine
Butylene Glycol
Tocopheryl Acetate
Magnesium Ascorbyl Phosphate
Sodium Hydroxide
Phenoxyethanol
Essential Oils
Water, Alcohol Denat., Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Salicylic Acid, Hamamelis Virginiana Water, Eugenia Caryophyllus Bud Oil, Origanum Heracleoticum Flower Oil, Eugenol, Limonene, Cucumis Sativus Fruit Extract, Pyrus Malus Fruit Extract, Scutellaria Baicalensis Root Extract, Algae Extract, Poria Cocos Sclerotium Extract, Laminaria Saccharina Extract, Lactobacillus Ferment, Glycerin, Caffeine, Butylene Glycol, Tocopheryl Acetate, Magnesium Ascorbyl Phosphate, Sodium Hydroxide, Phenoxyethanol, Essential Oils
Propylene Glycol
Benzoyl Peroxide
Bisabolol
Allantoin
Hydroxyethylcellulose
Sodium Citrate
Laureth-4
Caprylyl Glycol
Disodium EDTA
Hexylene Glycol
Water, Propylene Glycol, Benzoyl Peroxide, Bisabolol, Allantoin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Hydroxyethylcellulose, Sodium Citrate, Laureth-4, Caprylyl Glycol, Sodium Hydroxide, Disodium EDTA, Hexylene Glycol, Phenoxyethanol
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!