Paula's Choice 1% Retinol Treatment Versus Galderma Epiduo Gel 0.1%/2.5%

Paula's Choice 1% Retinol Treatment Versus Galderma Epiduo Gel 0.1%/2.5%

This anti-aging treatment is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dimethicone

Glycerin

Butylene Glycol

Isononyl Isononanoate

Castor Isostearate Succinate

Glyceryl Stearate

C12-15 Alkyl Benzoate

Dimethicone Crosspolymer

PEG-33

Polysorbate 20

Behenyl Alcohol

PEG-100 Stearate

Pentaerythrityl Tetraisostearate

Polymethylsilsesquioxane

Tetrahexyldecyl Ascorbate

Retinol

Ceramide Ng

Palmitoyl Tetrapeptide-7

Palmitoyl Hexapeptide-12

Sodium Hyaluronate

Dipotassium Glycyrrhizate

Glycyrrhiza Glabra Root Extract

Avena Sativa Kernel Extract

Arctium Lappa Seed Oil

Salix Alba Extract

Glycine Soja Sterols

Lecithin

Allantoin

Tocopheryl Acetate

Hydrolyzed Soy Protein

Sorbitan Laurate

Acetyl Dipeptide-1 Cetyl Ester

Disodium EDTA

Hydroxyethylcellulose

Palmitoyl Tripeptide-1

Sodium Hydroxide

Tribehenin

Caprylyl Glycol

Ethylhexylglycerin

Pentylene Glycol

PEG-75 Shea Butter Glycerides

PPG-12/Smdi Copolymer

PEG-10 Phytosterol

PEG-8 Dimethicone

PEG-14

Magnesium Aluminum Silicate

Arachidyl Glucoside

Arachidyl Alcohol

Sclerotium Gum

Carbomer

Phenoxyethanol

Benzoic Acid

Water, Dimethicone, Glycerin, Butylene Glycol, Isononyl Isononanoate, Castor Isostearate Succinate, Glyceryl Stearate, C12-15 Alkyl Benzoate, Dimethicone Crosspolymer, PEG-33, Polysorbate 20, Behenyl Alcohol, PEG-100 Stearate, Pentaerythrityl Tetraisostearate, Polymethylsilsesquioxane, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Seed Oil, Salix Alba Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Sorbitan Laurate, Acetyl Dipeptide-1 Cetyl Ester, Disodium EDTA, Hydroxyethylcellulose, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Ethylhexylglycerin, Pentylene Glycol, PEG-75 Shea Butter Glycerides, PPG-12/Smdi Copolymer, PEG-10 Phytosterol, PEG-8 Dimethicone, PEG-14, Magnesium Aluminum Silicate, Arachidyl Glucoside, Arachidyl Alcohol, Sclerotium Gum, Carbomer, Phenoxyethanol, Benzoic Acid

Adapalene 0.1%

Benzoyl Peroxide 2.5%

Hydrogen Peroxide

Diethylhexyl Sodium Sulfosuccinate

Poloxamer 407

Propylene Glycol

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

Isohexadecane

Polysorbate 80

Acrylamides Copolymer

Sodium Acryloyldimethyltaurate Crosspolymer

Sorbitan Oleate

Adapalene 0.1%, Benzoyl Peroxide 2.5%, Hydrogen Peroxide, Diethylhexyl Sodium Sulfosuccinate, Disodium EDTA, Glycerin, Poloxamer 407, Propylene Glycol, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Isohexadecane, Polysorbate 80, Acrylamides Copolymer, Sodium Acryloyldimethyltaurate Crosspolymer, Sorbitan Oleate, Water

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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