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Skin science article

Paula's Choice Barrier Repair Advanced Moisturizer Versus BYOMA Barrier+ Repair Treatment

Paula's Choice Barrier Repair Advanced Moisturizer Versus BYOMA Barrier+ Repair Treatment This barrier-repair moisturizer is formulated around Ceramide Ag and Ceramide NP to strengthen the skin barrier and hydrate skin. This barrier-repair treatment is formula

Paula's Choice Barrier Repair Advanced Moisturizer Versus BYOMA Barrier+ Repair Treatment

This barrier-repair moisturizer is formulated around Ceramide Ag and Ceramide NP to strengthen the skin barrier and hydrate skin.

This barrier-repair treatment is formulated around Ectoin and Sphingolipids to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

2,3-Butanediol

Dicaprylyl Carbonate

Glycerin

Glyceryl Stearate

Cocoglycerides

Ceramide Ag

Ceramide NP

Hydroxyacetophenone

Sodium Hyaluronate

Ceramide EOP

Ceramide Ng

Ceramide AP

Adenosine

Tocopherol

Butyrospermum Parkii Butter

Palmitoyl Tripeptide-5

Hexylene Glycol

Trehalose

Cholesterol

Squalane

Sodium Phytate

Urea

Hydrogenated Lecithin

Citrullus Lanatus Seed Oil

Caprylyl Glycol

Sodium PCA

Polyquaternium-51

Triacetin

Sodium Polyacrylate

Xanthan Gum

Ethylhexyl Stearate

Phenoxyethanol

Sodium Stearoyl Glutamate

Ethylhexylglycerin

Water, 2,3-Butanediol, Dicaprylyl Carbonate, Glycerin, Glyceryl Stearate, Cocoglycerides, Ceramide Ag, Ceramide NP, Hydroxyacetophenone, Sodium Hyaluronate, Ceramide EOP, Ceramide Ng, Ceramide AP, Adenosine, Tocopherol, Butyrospermum Parkii Butter, Palmitoyl Tripeptide-5, Hexylene Glycol, Trehalose, Cholesterol, Squalane, Sodium Phytate, Urea, Hydrogenated Lecithin, Citrullus Lanatus Seed Oil, Caprylyl Glycol, Sodium PCA, Polyquaternium-51, Triacetin, Sodium Polyacrylate, Xanthan Gum, Ethylhexyl Stearate, Phenoxyethanol, Sodium Stearoyl Glutamate, Ethylhexylglycerin

Butylene Glycol

Pentaerythrityl Tetraisostearate

Butylene Glycol Dicaprylate/Dicaprate

Diisostearyl Malate

Cetyl Ethylhexanoate

Methyl Trimethicone

Phenyl Trimethicone

Behenyl Alcohol

Cetearyl Olivate

Cetearyl Alcohol

Persea Gratissima Oil

Sorbitan Olivate

C14-22 Alcohols

Ectoin

Dipropylene Glycol

Simethicone

Sphingolipids

Arachidyl Glucoside

1,2-Hexanediol

Glucose

Polyacrylate-13

Palmitic Acid

Arachidyl Alcohol

C11-13 Isoparaffin

Stearic Acid

C12-20 Alkyl Glucoside

Hydrogenated Polyisobutene

Isohexadecane

Dimethiconol

Allantoin

Carbomer

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Tromethamine

Polyglyceryl-10 Laurate

Ethylhexyl Palmitate

Sorbitan Isostearate

Cyanocobalamin

Dipotassium Glycyrrhizate

Water, Glycerin, Butylene Glycol, Pentaerythrityl Tetraisostearate, Butylene Glycol Dicaprylate/Dicaprate, Diisostearyl Malate, Cetyl Ethylhexanoate, Methyl Trimethicone, Butyrospermum Parkii Butter, Phenyl Trimethicone, Behenyl Alcohol, Cetearyl Olivate, Cetearyl Alcohol, Squalane, Persea Gratissima Oil, Sorbitan Olivate, C14-22 Alcohols, Ectoin, Dipropylene Glycol, Simethicone, Ethylhexylglycerin, Sphingolipids, Arachidyl Glucoside, 1,2-Hexanediol, Glucose, Ceramide NP, Polyacrylate-13, Hydroxyacetophenone, Palmitic Acid, Arachidyl Alcohol, C11-13 Isoparaffin, Stearic Acid, C12-20 Alkyl Glucoside, Hydrogenated Polyisobutene, Isohexadecane, Caprylyl Glycol, Dimethiconol, Allantoin, Carbomer, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Tromethamine, Sodium Hyaluronate, Polyglyceryl-10 Laurate, Ethylhexyl Palmitate, Sorbitan Isostearate, Sodium Phytate, Cyanocobalamin, Dipotassium Glycyrrhizate, Tocopherol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.

Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).

In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).

Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.

Shea butter also contains vitamins A and E which may contribute to antioxidant activity.

While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.

This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.

As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.

Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.

This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.

You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.

Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.

An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.

So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.

Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Sodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.

Sodium Phytate is a chelating agent. Chelating agents help prevent metals from binding to water. This helps stabilize the ingredients and the product.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Butyl Methoxydibenzoylmethane 2%
  2. 02Ethylhexyl Methoxycinnamate 7.5%
  3. 03Ethylhexyl Salicylate 5%
  4. 04Octocrylene 2%
  5. 05Water
  6. 06Glycerin
  7. 07Silica
  8. 08Dimethicone
  9. 09Tocopherol
  10. 10Chamomilla Recutita Flower Extract
  11. 11Vitis Vinifera Seed Extract
  12. 12Camellia Sinensis Leaf Extract
  13. 13Camellia Oleifera Leaf Extract
  14. 14Peucedanum Graveolens Extract
  15. 15Sambucus Nigra Fruit Extract
  16. 16Avena Sativa Bran Extract
  17. 17Punica Granatum Extract
  18. 18Lycium Barbarum Fruit Extract
  19. 19Hydrogenated Lecithin
  20. 20Titanium Dioxide
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side