Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Versus Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant

Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Versus Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant This anti-aging treatment is formulated around Bakuchiol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin te

Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Versus Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant

This anti-aging treatment is formulated around Bakuchiol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture.

This smoothing exfoliator is formulated around Salicylic Acid to refine skin texture and refine the look of pores.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dimethicone

Pentaerythrityl Tetraisostearate

Isononyl Isononanoate

Butylene Glycol

Bakuchiol

Arachidyl Alcohol

Glyceryl Polymethacrylate

Dimethicone Crosspolymer

Behenyl Alcohol

Glycerin

PEG-75 Shea Butter Glycerides

Glyceryl Stearate

C12-15 Alkyl Benzoate

Polysorbate 20

Tetrahexyldecyl Ascorbate

Retinol

Ceramide Ng

Palmitoyl Tetrapeptide-7

Palmitoyl Hexapeptide-12

Sodium Hyaluronate

Dipotassium Glycyrrhizate

Glycyrrhiza Glabra Root Extract

Avena Sativa Kernel Extract

Arctium Lappa Root Extract

Salix Alba Bark Extract

Glycine Soja Sterols

Lecithin

Allantoin

Tocopheryl Acetate

Hydrolyzed Soy Protein

Palmitoyl Tripeptide-1

Sodium Hydroxide

Tribehenin

Caprylyl Glycol

Dipeptide-2

Polygonum Cuspidatum Root Extract

PEG-10 Phytosterol

PEG-8

Magnesium Aluminum Silicate

Arachidyl Glucoside

Chrysin

Pentylene Glycol

Sodium Acrylates Copolymer

Steareth-20

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Cetearyl Alcohol

Coco-Glucoside

Hesperidin Methyl Chalcone

N-Hydroxysuccinimide

Disodium EDTA

Phenoxyethanol

Benzoic Acid

Ethylhexylglycerin

Water, Dimethicone, Pentaerythrityl Tetraisostearate, Isononyl Isononanoate, Butylene Glycol, Bakuchiol, Arachidyl Alcohol, Glyceryl Polymethacrylate, Dimethicone Crosspolymer, Behenyl Alcohol, Glycerin, PEG-75 Shea Butter Glycerides, Glyceryl Stearate, C12-15 Alkyl Benzoate, Polysorbate 20, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Root Extract, Salix Alba Bark Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Dipeptide-2, Polygonum Cuspidatum Root Extract, PEG-10 Phytosterol, PEG-8, Magnesium Aluminum Silicate, Arachidyl Glucoside, Chrysin, Pentylene Glycol, Sodium Acrylates Copolymer, Steareth-20, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, Coco-Glucoside, Hesperidin Methyl Chalcone, N-Hydroxysuccinimide, Disodium EDTA, Phenoxyethanol, Benzoic Acid, Ethylhexylglycerin

Methylpropanediol

Salicylic Acid

Camellia Oleifera Leaf

Tetrasodium EDTA

Water, Methylpropanediol, Butylene Glycol, Salicylic Acid, Polysorbate 20, Camellia Oleifera Leaf, Sodium Hydroxide, Tetrasodium EDTA

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.

It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.

The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.

Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).

True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.

Because it is derived from lauric acid, it may not be fungal acne safe.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
  4. 04Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
  5. 05It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
  6. 06Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
  7. 07A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
  8. 08Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
  9. 09Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
  10. 10This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
  11. 11A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
  12. 12Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
  13. 13Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
  14. 14Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
  15. 15Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
  16. 16Its main roles are:
  17. 17Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.
  18. 18The FDA allows products labeled "alcohol-free" to have fatty alcohols.
  19. 19This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.
  20. 20Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side