Paula's Choice Clinical Niacinamide 20% Treatment Versus La Roche-Posay Effaclar Salicylic Acid Acne Treatment Serum

Paula's Choice Clinical Niacinamide 20% Treatment Versus La Roche-Posay Effaclar Salicylic Acid Acne Treatment Serum

This pore-care treatment is formulated around Niacinamide and Acetyl Glucosamine to refine the look of pores and refine skin texture.

This acne treatment is formulated around Glycolic Acid and Niacinamide to clear breakouts and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Niacinamide 20%

Pentylene Glycol

Butylene Glycol

Glycerin

Acetyl Glucosamine

Ascorbyl Glucoside

Glycyrrhiza Glabra Root Extract

Spiraea Ulmaria Extract

Portulaca Oleracea Extract

Camellia Japonica Flower Extract

Epigallocatechin Gallate

Boerhavia Diffusa Root Extract

Camellia Sinensis Leaf Extract

Allantoin

Lecithin

Pullulan

Panthenol

Silica

Xanthan Gum

Sclerotium Gum

Propanediol

Sodium Phytate

Phenoxyethanol

Ethylhexylglycerin

Water, Niacinamide 20%, Pentylene Glycol, Butylene Glycol, Glycerin, Acetyl Glucosamine, Ascorbyl Glucoside, Glycyrrhiza Glabra Root Extract, Spiraea Ulmaria Extract, Portulaca Oleracea Extract, Camellia Japonica Flower Extract, Epigallocatechin Gallate, Boerhavia Diffusa Root Extract, Camellia Sinensis Leaf Extract, Allantoin, Lecithin, Pullulan, Panthenol, Silica, Xanthan Gum, Sclerotium Gum, Propanediol, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin

Alcohol Denat.

Glycolic Acid

Niacinamide

Dimethyl Isosorbide

Sodium Hydroxide

PPG-26-Buteth-26

Hydroxyethylpiperazine Ethane Sulfonic Acid

Citric Acid

PEG-30 Glyceryl Cocoate

PEG-40 Hydrogenated Castor Oil

PEG-60 Hydrogenated Castor Oil

Capryloyl Salicylic Acid

Biosaccharide Gum-1

Maltodextrin

Phytic Acid

Polyquaternium-10

Parfum

Water, Alcohol Denat., Propanediol, Glycolic Acid, Niacinamide, Dimethyl Isosorbide, Pentylene Glycol, Sodium Hydroxide, PPG-26-Buteth-26, Hydroxyethylpiperazine Ethane Sulfonic Acid, Citric Acid, PEG-30 Glyceryl Cocoate, PEG-40 Hydrogenated Castor Oil, PEG-60 Hydrogenated Castor Oil, Capryloyl Salicylic Acid, Biosaccharide Gum-1, Maltodextrin, Phytic Acid, Polyquaternium-10, Parfum

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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