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Skin science article

Paula's Choice Defense Essential Glow Moisturizer SPF 30 Versus Paula's Choice Skin Balancing Ultra-Sheer Daily Defense Broad Spectrum SPF 30

Paula's Choice Defense Essential Glow Moisturizer SPF 30 Versus Paula's Choice Skin Balancing Ultra-Sheer Daily Defense Broad Spectrum SPF 30 This brightening moisturizer is formulated around Glycyrrhiza Glabra Root Extract and Tetrapeptide-30 to brighten dull

Paula's Choice Defense Essential Glow Moisturizer SPF 30 Versus Paula's Choice Skin Balancing Ultra-Sheer Daily Defense Broad Spectrum SPF 30

This brightening moisturizer is formulated around Glycyrrhiza Glabra Root Extract and Tetrapeptide-30 to brighten dull-looking skin and fade the look of dark spots.

This oil-control day moisturizer is formulated around Aluminum Starch Octenylsuccinate and Camellia Sinensis Leaf Extract to balance excess oil and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

C12-15 Alkyl Benzoate

Zinc Oxide

Titanium Dioxide

Glycerin

Isononyl Isononanoate

Butylene Glycol

Cetearyl Alcohol

Potassium Cetyl Phosphate

Dimethicone

Glyceryl Stearate

Glycyrrhiza Glabra Root Extract

Actinidia Chinensis Fruit Extract

Argania Spinosa Kernel Oil

Tetrapeptide-30

Linoleic Acid

Resveratrol

Ascorbyl Glucoside

Niacinamide

Tocopheryl Acetate

Magnesium Ascorbyl Phosphate

Bisabolol

Tocopherol

Phospholipids

Lecithin

Glycine Soja Sterols

Xanthophylls

Pullulan

Sodium Gluconate

Xanthan Gum

Sclerotium Gum

Alumina

Caprylic/Capric Triglyceride

Citric Acid

Triethoxycaprylylsilane

C13-14 Isoparaffin

Acrylates Copolymer

Polyhydroxystearic Acid

Caprylyl Glycol

Polyacrylamide

Ceteareth-20

Aluminum Stearate

Laureth-7

Ethylhexylglycerin

Phenoxyethanol

Water, C12-15 Alkyl Benzoate, Zinc Oxide, Titanium Dioxide, Glycerin, Isononyl Isononanoate, Butylene Glycol, Cetearyl Alcohol, Potassium Cetyl Phosphate, Dimethicone, Glyceryl Stearate, Glycyrrhiza Glabra Root Extract, Actinidia Chinensis Fruit Extract, Argania Spinosa Kernel Oil, Tetrapeptide-30, Linoleic Acid, Resveratrol, Ascorbyl Glucoside, Niacinamide, Tocopheryl Acetate, Magnesium Ascorbyl Phosphate, Bisabolol, Tocopherol, Phospholipids, Lecithin, Glycine Soja Sterols, Xanthophylls, Pullulan, Sodium Gluconate, Xanthan Gum, Sclerotium Gum, Alumina, Caprylic/Capric Triglyceride, Citric Acid, Triethoxycaprylylsilane, C13-14 Isoparaffin, Acrylates Copolymer, Polyhydroxystearic Acid, Caprylyl Glycol, Polyacrylamide, Ceteareth-20, Aluminum Stearate, Laureth-7, Ethylhexylglycerin, Phenoxyethanol

Homosalate

Benzophenone-3

Butyl Methoxydibenzoylmethane

Silica

Octocrylene

Aluminum Starch Octenylsuccinate

Cetyl Dimethicone

Camellia Sinensis Leaf Extract

Aloe Barbadensis Leaf Juice Powder

Ascorbyl Palmitate

Superoxide Dismutase

Adenosine

Boerhavia Diffusa Root Extract

Avena Sativa Kernel Extract

Panthenol

Ginkgo Biloba Leaf Extract

Salix Alba Bark Extract

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Sodium Hydroxide

Steareth-21

Steareth-2

Polysorbate 20

Disodium EDTA

Sorbic Acid

Water, Homosalate, Butylene Glycol, Benzophenone-3, Butyl Methoxydibenzoylmethane, Silica, Octocrylene, Aluminum Starch Octenylsuccinate, Cetyl Dimethicone, Camellia Sinensis Leaf Extract, Aloe Barbadensis Leaf Juice Powder, Ascorbyl Palmitate, Phospholipids, Superoxide Dismutase, Adenosine, Tocopherol, Bisabolol, Boerhavia Diffusa Root Extract, Avena Sativa Kernel Extract, Panthenol, Ginkgo Biloba Leaf Extract, Salix Alba Bark Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Titanium Dioxide, Sodium Hydroxide, Steareth-21, Steareth-2, Polysorbate 20, Disodium EDTA, Phenoxyethanol, Sorbic Acid

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient.

It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation.

A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.

In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.

You'll likely see use concentrations quite low, usually 0.1-0.2%.

Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Phospholipids are a family of skin-identical lipids that makeup the structural backbone of every cell membrane in your body.

In cosmetics, they function as skin conditioning agents with emulsifier and surfactant properties. They're typically sourced from soybean or sunflower lecithin (or sometimes egg yolk or marine sources).

Because they mirror the lipids naturally found in the deeper layers of your skin, topical phospholipids help reinforce the lipid matrix, reduce transepidermal water loss, and leave skin feeling conditioned.

They're also used to form liposomes, or tiny self-assembling vesible used to stabilize actives like vitamin c or retinol. This helps these ingredients integrate into the upper layers of skin more easily.

Phospholipids are compatible with everything and the CIR Expert Panel has concluded them to be safe at current use levels.

Some types of phospholipids include:

Titanium Dioxide (TD) is a mineral UV filter widely used in sunscreens and cosmetics.

It's one of only two UV filters officially classified as "mineral" by regulatory agencies (the other being Zinc Oxide).

A really common myth is that mineral filters work by reflecting UV light off your skin like tiny mirrors.

They don't only do that; modern research shows TD protects mostly by absorbing UV radiation, the same way chemical filters do.

When researchers measured this, reflection accounted for only about 4-5% of the protection (and less than SPF 2 on its own). The other ~95% comes from absorption: the UV photons hit the particle and their energy gets soaked up by its semiconductor band gap rather than bouncing off.

So "reflects vs. absorbs" was never really the right way to split mineral from chemical filters.

TD gives broad-spectrum protection that's strongest in the UVB and UVA-2 range and weaker in the UVA-1 range. Its UVA protection isn't quite as strong as Zinc Oxide's which is why you'll often see the two paired together.

Together, they make a solid broad-spectrum system.

TD is a great pick for sensitive, acne-prone, or redness-prone skin because it's non-irritating and chemically inert. Regulatory reviews classify it as a non-sensitizer and mild-to-non-irritant.

It's also unlikely to cause the "eye sting" some chemical filters are known for.

The main trade-off is cosmetic; TD can leave a white cast and has a thicker texture. This is why mineral sunscreens are often less cosmetically elegant than chemical or hybrid formulas (and harder to shade-match on deeper skin tones).

Formulators often use micronized or nano-sized TD to cut down on white case and improve spreadability. Smaller particles scatter less visible light so the formula looks less chalky while still filtering UV.

TD is almost always bundled with coatings like Alumina, Silica, Stearic Acid, or Dimethicone. These coatings do two important jobs:

TD can be used at up to 25% in a finished sunscreen; this is the regulatory ceiling in both the US and the EU.

In practice, the amount in any given product varies a lot depending on the target SPF and whether it's paired with other UV filters.

TD is one of the most heavily vetted sunscreen ingredients out there. It is approved as a UV filter in all major markets worldwide, including the US, EU, UK, Japan, Korea, China, Australia, and Canada.

The safety evidence is solid. There was an old worry that nano particles might absorb through skin into the body but multiple studies (including on damaged, sunburned, and UV-irradiated skin) have shown that TD stays on the surface and the layer of dead skin cells on top of everything else.

There's also no evidence of carcinogenicity, mutagenicity, or reproductive toxicity from dermal exposure of this ingredient.

For those who have seen the headline about a 2022 EU ban on TD, that was on TD as a food additive (a complete separate use from topical sunscreen).

There are ongoing questions about how nano-TD might affect marine ecosystems. As of now, there has been no conclusive evidence that any form of TD (or any other sunscreen filter) harms coral reefs or marine life.

The science is still developing and it's a space worth watching rather than packing over.

However, several destinations have reef-safety sunscreen rules that restrict certain chemical filters and steer visitors toward mineral, non-nano options. If you're traveling somewhere with these rules, a non-nano mineral sunscreen is the safe bet.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Paula's Choice 1% Retinol TreatmentIngredients explained

  1. 01The extract coming from the bark of the White Willow, a big (25 m/80 ft.) tree that likes to live on riverbanks. It's famous for containing anti-inflammatory natural salicylates (this powder, for example, is standardized to contain 53-65%), a close …
  2. 02Thanks to its salicin content, willow bark is often touted as a natural alternative to salicylic acid, though it's quite questionable how effective it is as a chemical exfoliant in the tiny amounts used in cosmetics. Apart from soothing salicin, it …
  3. 03The salt form of one of the main anti-inflammatory ingredients in the licorice plant, monoammonium glycyrrhizinate. It’s a yellowish powder with a nice sweet smell.
  4. 04It’s used mainly for its soothing and anti-inflammatory properties, but according to manufacturer info, it’s also sebum regulating so it's a perfect ingredient for problem skin products.
  5. 05Expand to read more
  6. 06Read more about licorice and why it's a skincare superstar here.
  7. 07Burdock root is a goodie plant extract that has anti-inflammatory and antioxidant properties. Also, it has some anti-fungal and seborrhea regulation magic powers that make the ingredient especially useful for greasy and flaky skin and scalp.
  8. 08We don't have description for this ingredient yet.
  9. 09Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of skincare big shot Vitamin C. If you do not know, why Vitamin C is such a big deal in skincare, click here and read all about it. We are massive vitamin C fans and have written about it in ex…
  10. 10So now, you know that Vitamin C is great and all, but it's really unstable and gives cosmetics companies many headaches. To solve this problem they came up with vitamin C derivatives, and one of them is Tetrahexyldecyl Ascorbate (let's call it THDA …
  11. 11It's a really promising candidate (see below), but while reading all the goodness about it in a minute, do not forget that derivatives not only have to be absorbed into the skin but also have to be converted to pure vitamin C (ascorbic acid or AA) a…
  12. 12With this context in mind let's see what THDA might be able to do. First, it is stable (if pH < 5), easy to formulate, and a joy to work with for a cosmetic chemist.
  13. 13Second, because it's oil-soluble, its skin penetration abilities seem to be great. So great in fact, that it surpasses the penetration of pure vitamin C threefold at the same concentration and it penetrates successfully into the deeper layers of the…
  14. 14Third, THDA seems to have all three magic abilities of pure vitamin C: it gives antioxidant protection from both UVB and UVA rays, it increases collagen synthesis (even more than AA) and it has a skin brightening effect by reducing melanogenesis by …
  15. 15So this all sounds really great, but these are only in-vitro results at this point. We could find Tetrahexyldecyl Ascorbate mentioned only in one published in-vivo study that examined the anti-aging properties of a silicone formula containing 10% AA…
  16. 16Bottom line: a really promising, but not well-proven vitamin C derivative that can be worth a try especially if you like experimenting (but if you like the tried and true, pure vitamin C will be your best bet).
  17. 17Retinol (pure Vitamin A) is probably the most proven anti-aging ingredient available OTC
  18. 18It has to be converted in the skin to retinoic acid to work its magic
  19. 19Once converted, it has the same effect as all-trans-retinoic acid, aka tretinoin
  20. 20A generally accepted ballpark number is that retinol is 10-to-20 times less potent than retinoic acid
Source · incidecoder.com
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Product index

Related product references

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Comparison edit

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