Paula's Choice Omega+ Complex Serum Versus Rodan + Fields Active Hydration Serum

Paula's Choice Omega+ Complex Serum Versus Rodan + Fields Active Hydration Serum

This barrier-repair serum is formulated around Linoleic Acid and Linolenic Acid to strengthen the skin barrier and hydrate skin.

This hydrating serum is formulated around Sodium Hyaluronate and Ceramide NP to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Diheptyl Succinate

Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters

Linum Usitatissimum Seed Oil

Linoleic Acid

Linolenic Acid

Passiflora Edulis Seed Oil

Ceramide EOP

Ceramide Eos

Ceramide NP

Ceramide Ns

Caprooyl Sphingosine

Olea Europaea Oil Unsaponifiables

Caprooyl Phytosphingosine

Sodium Hyaluronate

Cholesterol

Ceramide AP

Butyrospermum Parkii Butter Unsaponifiables

Tocopherol

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Prunus Domestica Seed Oil

Lauryl Laurate

Glyceryl Behenate

Hydrogenated Lecithin

Sodium Phytate

Trehalose

Isohexadecane

Sodium Stearoyl Lactylate

Capryloyl Glycerin/Sebacic Acid Copolymer

Xanthan Gum

Cetyl Alcohol

Tetrahexyldecyl Ascorbate

Agar

Glyceryl Stearate

Ceteareth-25

Cetearyl Alcohol

Behenic Acid

Glyceryl Rosinate

Citric Acid

Benzyl Alcohol

Ethylhexylglycerin

Water, Glycerin, Diheptyl Succinate, Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters, Linum Usitatissimum Seed Oil, Linoleic Acid, Linolenic Acid, Passiflora Edulis Seed Oil, Ceramide EOP, Ceramide Eos, Ceramide NP, Ceramide Ns, Caprooyl Sphingosine, Olea Europaea Oil Unsaponifiables, Caprooyl Phytosphingosine, Sodium Hyaluronate, Cholesterol, Ceramide AP, Butyrospermum Parkii Butter Unsaponifiables, Tocopherol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Prunus Domestica Seed Oil, Lauryl Laurate, Glyceryl Behenate, Hydrogenated Lecithin, Sodium Phytate, Trehalose, Isohexadecane, Sodium Stearoyl Lactylate, Capryloyl Glycerin/Sebacic Acid Copolymer, Xanthan Gum, Cetyl Alcohol, Tetrahexyldecyl Ascorbate, Agar, Glyceryl Stearate, Ceteareth-25, Cetearyl Alcohol, Behenic Acid, Glyceryl Rosinate, Citric Acid, Benzyl Alcohol, Ethylhexylglycerin

Bis-PEG-12 Dimethicone

Pentylene Glycol

Pyrus Malus Fruit Extract

Adenosine

Ascorbyl Palmitate

Maris Sal

Cetyl Hydroxyethylcellulose

Calcium PCA

Magnesium PCA

Lecithin

Gellan Gum

Lactic Acid

Hydrated Silica

Silica Dimethyl Silylate

Disodium Phosphate

Parfum

Hexylene Glycol

Caprylyl Glycol

Sodium Benzoate

Phenoxyethanol

Butylphenyl Methylpropional

Limonene

Water, Glycerin, Bis-PEG-12 Dimethicone, Pentylene Glycol, Pyrus Malus Fruit Extract, Sodium Hyaluronate, Adenosine, Ceramide NP, Ceramide Ns, Ceramide AP, Ceramide EOP, Ceramide Eos, Tocopherol, Ascorbyl Palmitate, Maris Sal, Cetyl Hydroxyethylcellulose, Calcium PCA, Magnesium PCA, Lecithin, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Gellan Gum, Ceteareth-25, Lactic Acid, Cetyl Alcohol, Behenic Acid, Cholesterol, Hydrated Silica, Silica Dimethyl Silylate, Disodium Phosphate, Parfum, Hexylene Glycol, Ethylhexylglycerin, Caprylyl Glycol, Sodium Benzoate, Phenoxyethanol, Butylphenyl Methylpropional, Limonene

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Behenic acid is a long-chain fatty acid with 22 carbon atoms (C22) that is naturally found in moringa, rapeseed, and peanut oil.

In skincare, it's about as drama-free as ingredients come. It acts primarily as a texture enhancer, thickener, and opacifying agent that gives richness and viscosity to formulas.

On skin, it forms a protective, emollient layer that helps with moisture retention and contributes to barrier integrity.

In vitro studies on genotoxicity have come back negative and this ingredient is well-tolerated. Typical use concentrations range from 0.024%-22%.

This ingredient may not be fungal acne safe because Behenic acid falls within the C11-24 fatty acid range capable of supporting Malassezia growth.

This ceramide helps condition and moisturize skin.

It is created by reacting caproic acid and phytosphingosine, two fatty acids.

Ceramides work to improve hydration from within. Their lipophilic trait means they are likely to be absorbed into skin but expected to remain in the epidermis (the outer layer of skin).

We don't have a description for Caprooyl Sphingosine yet.

Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function.

You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has.

The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.

Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.

Ceramide EOP is formally known as Ceramide 1.

It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer.

EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.

What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do).

Low levels of Ceramide EOP have been found in people with eczema and psoriasis.

Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss.

In one clinical study, a regimen using Ceramide EOP, NP, and AP led to significant symptom improvements in patients with eczema, psoriasis, and dry skin in just 4 weeks.

You'll usually see concentrations between 0.1-0.5% in formulations. Overall, this is a well-tolerated and safe ingredient for cosmetic use.

Ceramide EOS is a type of Ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramide EOS is a synthetic N-acylated sphingolipid consisting of Sphingosine having the D-erythro structure linked to an esterified omega-hydroxy saturated or unsaturated fatty acid

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Ceramide NS is formally known as Ceramide 2. It is one of the major ceramides in the stratum corneum (outermost layer of skin) plays a role in forming a protective barrier.

Due to its structure, skin lipids can be packed tightly and in turn, this strengthens the barrier and reduces water loss.

Studies show conditions like atopic dermatitis can worsen when ceramide NS levels are low.

Ceteareth-25 comes from Cetearyl Alcohol. (And Cetearyl Alcohol is created from cetyl alcohol and stearyl alcohol.

This ingredient is a fatty alcohol used as an emulsifier and surfactant. As an emulsifier, it helps oil mix with water.

Like cetearyl alcohol, Ceteareth-25 can help thicken and create a gel-like consistency.

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

Its main roles are:

Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.

The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.

Cholesterol is a lipid that is naturally found in human skin and is one of the three key components of your skin barrier. In skincare, it is an emollient and barrier-repairing ingredient.

It works by fitting directly into the lipid layers of skin to help restore structure and reduce transepidermal water loss (TEWL).

This is a great ingredient for dry, compromised, or aging skin; our skin starts to produce less cholesterol with age.

Research shows cholesterol works best in combination with ceramides and fatty acids, the other two major components in your skin barrier.

Cholesterol is also a well-establish penetration enhancer and can help other actives absorb more effectively.

Cosmetic-grade cholesterol is usually derived from lanolin but plant and synthetic options also exist. We recommend reaching out to the brand if you have questions about their source of cholesterol.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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