Skin science article
Paula's Choice Pro-Collagen Multi-Peptide Booster Versus Good Molecules Super Peptide Serum
Paula's Choice Pro-Collagen Multi-Peptide Booster Versus Good Molecules Super Peptide Serum This anti-aging serum is formulated around Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Ace
Paula's Choice Pro-Collagen Multi-Peptide Booster Versus Good Molecules Super Peptide Serum
This anti-aging serum is formulated around Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture.
This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Acetyl Octapeptide-3 to soften the look of wrinkles and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Glycerin
Pentylene Glycol
Hydrolyzed Yeast Extract
Pyrus Malus Fruit Extract
Dimethicone
Propanediol
1,2-Hexanediol
Glyceryl Glucoside
Palmitoyl Tripeptide-71 Amide
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
Sh-Polypeptide-121
Palmitoyl Tripeptide-5
Tridecapeptide-1
Polyglucuronic Acid
Sodium Hyaluronate
Dodecane
Ammonium Polyacryloyldimethyl Taurate
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
Polygonum Bistorta Root Extract
Bacillus Ferment
Lecithin
Butylene Glycol
Sodium Phytate
Coco-Caprylate/Caprate
Hexylene Glycol
Cetyl Hydroxyethylcellulose
Xanthan Gum
Ethylhexylglycerin
Caprylyl Glycol
Magnesium Chloride
Potassium Sorbate
Sodium Benzoate
Water, Glycerin, Pentylene Glycol, Hydrolyzed Yeast Extract, Pyrus Malus Fruit Extract, Dimethicone, Propanediol, 1,2-Hexanediol, Glyceryl Glucoside, Palmitoyl Tripeptide-71 Amide, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Sh-Polypeptide-121, Palmitoyl Tripeptide-5, Tridecapeptide-1, Polyglucuronic Acid, Sodium Hyaluronate, Dodecane, Ammonium Polyacryloyldimethyl Taurate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Polygonum Bistorta Root Extract, Bacillus Ferment, Lecithin, Butylene Glycol, Sodium Phytate, Coco-Caprylate/Caprate, Hexylene Glycol, Cetyl Hydroxyethylcellulose, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Magnesium Chloride, Potassium Sorbate, Sodium Benzoate
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Diheptyl Succinate
Capryloyl Glycerin/Sebacic Acid Copolymer
Glycine
Acetyl Hexapeptide-8
Acetyl Octapeptide-3
Copper Tripeptide-1
Tocopherol
Water, Propanediol, Glycerin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, 1,2-Hexanediol, Diheptyl Succinate, Capryloyl Glycerin/Sebacic Acid Copolymer, Glycine, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Sodium Hyaluronate, Copper Tripeptide-1, Tocopherol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.