Skin science article
Paula's Choice Pro-Collagen Peptide Plumping Moisturizer Versus Olehenriksen Après Skin Multi-Use Rescue Crème Overnight Moisturizer
Paula's Choice Pro-Collagen Peptide Plumping Moisturizer Versus Olehenriksen Après Skin Multi-Use Rescue Crème Overnight Moisturizer This anti-aging moisturizer is formulated around Squalane to soften the look of wrinkles and hydrate skin. This barrier-repair
Paula's Choice Pro-Collagen Peptide Plumping Moisturizer Versus Olehenriksen Après Skin Multi-Use Rescue Crème Overnight Moisturizer
This anti-aging moisturizer is formulated around Squalane to soften the look of wrinkles and hydrate skin.
This barrier-repair night moisturizer is formulated around Panthenol and Niacinamide to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Dimethicone
Squalane
Glycerin
Pyrus Malus Fruit Extract
Pentylene Glycol
1,2-Hexanediol
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Butylene Glycol
Hydroxyacetophenone
Sodium Acrylates Copolymer
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Gigartina Stellata Extract
Acetyl Sh-Hexapeptide-5 Amide Acetate
Tridecapeptide-1
Oligopeptide-1
Sodium Phytate
Propanediol
Lecithin
Hydroxypropyltrimonium Hyaluronate
Cyanocobalamin
Phenoxyethanol
Water, Dimethicone, Squalane, Glycerin, Pyrus Malus Fruit Extract, Pentylene Glycol, 1,2-Hexanediol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Butylene Glycol, Hydroxyacetophenone, Sodium Acrylates Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Gigartina Stellata Extract, Acetyl Sh-Hexapeptide-5 Amide Acetate, Tridecapeptide-1, Oligopeptide-1, Sodium Phytate, Propanediol, Lecithin, Hydroxypropyltrimonium Hyaluronate, Cyanocobalamin, Phenoxyethanol
Panthenol
Cetearyl Alcohol
Octyldodecanol
Dicaprylyl Carbonate
Butyrospermum Parkii Butter
Dicaprylyl Ether
Glyceryl Stearate Citrate
Niacinamide
Cetearyl Olivate
Sambucus Nigra Seed Oil
Tocopheryl Acetate
Mangifera Indica Seed Butter
Astrocaryum Murumuru Seed Butter
Rubus Chamaemorus Seed Oil
Ribes Nigrum Seed Oil
Sodium Hyaluronate
Polyglutamic Acid
Ceramide Ng
Ceramide NP
Ceramide AP
Ceramide EOP
Zinc PCA
Sodium PCA
Magnesium PCA
Manganese PCA
Saccharomyces/Zinc Ferment
Saccharomyces/Copper Ferment
Saccharomyces/Iron Ferment
Saccharomyces/Potassium Ferment
Saccharomyces/Silicon Ferment
Saccharomyces/Manganese Ferment
Tocopherol
Sodium Lactate
Linoleic Acid
Linolenic Acid
Sodium Lauroyl Lactylate
Phytosphingosine
Cholesterol
Sorbitan Olivate
Caprylyl Glycol
Polyacrylate Crosspolymer-6
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Xanthan Gum
Carbomer
Ethylhexylglycerin
Potassium Sorbate
Parfum
Leuconostoc/Radish Root Ferment Filtrate
Citral
Limonene
Linalool
Water, Panthenol, Cetearyl Alcohol, Glycerin, Octyldodecanol, Dicaprylyl Carbonate, Butyrospermum Parkii Butter, Propanediol, Dicaprylyl Ether, Glyceryl Stearate Citrate, Niacinamide, Cetearyl Olivate, Sambucus Nigra Seed Oil, Tocopheryl Acetate, Mangifera Indica Seed Butter, Astrocaryum Murumuru Seed Butter, Rubus Chamaemorus Seed Oil, Ribes Nigrum Seed Oil, Sodium Hyaluronate, Polyglutamic Acid, Ceramide Ng, Ceramide NP, Ceramide AP, Ceramide EOP, Zinc PCA, Sodium PCA, Magnesium PCA, Manganese PCA, Saccharomyces/Zinc Ferment, Saccharomyces/Copper Ferment, Saccharomyces/Iron Ferment, Saccharomyces/Potassium Ferment, Saccharomyces/Silicon Ferment, Saccharomyces/Manganese Ferment, Tocopherol, Cyanocobalamin, Sodium Lactate, Linoleic Acid, Linolenic Acid, Sodium Lauroyl Lactylate, Phytosphingosine, Cholesterol, Sorbitan Olivate, Caprylyl Glycol, Hydroxyacetophenone, Polyacrylate Crosspolymer-6, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Xanthan Gum, Dimethicone, Carbomer, Ethylhexylglycerin, Potassium Sorbate, Phenoxyethanol, Parfum, Leuconostoc/Radish Root Ferment Filtrate, Citral, Limonene, Linalool
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Cyanocobalamin is the manufactured version of vitamin B12. It has skin soothing, antioxidant, and barrier protecting properties. Topical cyanocobalamin is used to treat skin irritation and atopic dermatitis.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.
As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.
Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.
This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.
You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.
Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.
An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.
So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.
Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!