Skin science article
Paula's Choice Pro-Collagen Peptide Plumping Moisturizer Versus PURITO Dermide Relief Barrier Moisturizer
Paula's Choice Pro-Collagen Peptide Plumping Moisturizer Versus PURITO Dermide Relief Barrier Moisturizer This anti-aging moisturizer is formulated around Squalane to soften the look of wrinkles and hydrate skin. This barrier-repair moisturizer is formulated a
Paula's Choice Pro-Collagen Peptide Plumping Moisturizer Versus PURITO Dermide Relief Barrier Moisturizer
This anti-aging moisturizer is formulated around Squalane to soften the look of wrinkles and hydrate skin.
This barrier-repair moisturizer is formulated around Ceramide NP and Allantoin to strengthen the skin barrier and calm redness.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Dimethicone
Squalane
Glycerin
Pyrus Malus Fruit Extract
Pentylene Glycol
1,2-Hexanediol
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Butylene Glycol
Hydroxyacetophenone
Sodium Acrylates Copolymer
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Gigartina Stellata Extract
Acetyl Sh-Hexapeptide-5 Amide Acetate
Tridecapeptide-1
Oligopeptide-1
Sodium Phytate
Propanediol
Lecithin
Hydroxypropyltrimonium Hyaluronate
Cyanocobalamin
Phenoxyethanol
Water, Dimethicone, Squalane, Glycerin, Pyrus Malus Fruit Extract, Pentylene Glycol, 1,2-Hexanediol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Butylene Glycol, Hydroxyacetophenone, Sodium Acrylates Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Gigartina Stellata Extract, Acetyl Sh-Hexapeptide-5 Amide Acetate, Tridecapeptide-1, Oligopeptide-1, Sodium Phytate, Propanediol, Lecithin, Hydroxypropyltrimonium Hyaluronate, Cyanocobalamin, Phenoxyethanol
Caprylic/Capric Triglyceride
Hydrogenated Poly(C6-14 Olefin)
Behenyl Alcohol
Limnanthes Alba Seed Oil
Polyglyceryl-6 Stearate
Cetyl Alcohol
Candida/Garcinia Cambogia Ferment
Ceramide NP
Glyceryl Stearate
Polyglyceryl-6 Behenate
Allantoin
Caprylyl Glycol
Panthenol
Macadamia Ternifolia Seed Oil
Xanthan Gum
Butyrospermum Parkii Butter
Ethylhexylglycerin
Disodium EDTA
Dipropylene Glycol
Hydrogenated Lecithin
Ceramide Ns
Ceramide As
Ceramide AP
Cholesterol
Ceramide EOP
Water, Propanediol, Glycerin, Caprylic/Capric Triglyceride, Hydrogenated Poly(C6-14 Olefin), Behenyl Alcohol, Limnanthes Alba Seed Oil, Polyglyceryl-6 Stearate, 1,2-Hexanediol, Cetyl Alcohol, Candida/Garcinia Cambogia Ferment, Ceramide NP, Glyceryl Stearate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Polyglyceryl-6 Behenate, Allantoin, Squalane, Caprylyl Glycol, Panthenol, Macadamia Ternifolia Seed Oil, Xanthan Gum, Butyrospermum Parkii Butter, Ethylhexylglycerin, Disodium EDTA, Dipropylene Glycol, Hydrogenated Lecithin, Ceramide Ns, Ceramide As, Ceramide AP, Cholesterol, Ceramide EOP
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Ammonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.
Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy.
The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's:
Due to its large molecular size, it sits on the surface of skin rather than penetrating it.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!