Paula's Choice RESIST Advanced Smoothing Treatment 10% AHA Versus CeraVe SA Cream for Rough & Bumpy Skin

Paula's Choice RESIST Advanced Smoothing Treatment 10% AHA Versus CeraVe SA Cream for Rough & Bumpy Skin

This smoothing treatment is formulated around Glycolic Acid and Lactic Acid to refine skin texture and soften the look of wrinkles.

This smoothing moisturizer is formulated around Salicylic Acid and Niacinamide to refine skin texture and clear breakouts.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Glycolic Acid

Glycerin

Lactic Acid

Caprylic/Capric Triglyceride

Malic Acid

Tartaric Acid

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Ceramide Ng

Salicylic Acid

Glycyrrhiza Glabra Root

Camellia Sinensis Leaf Extract

Punica Granatum Extract

Lycium Barbarum Fruit Extract

Vitis Vinifera Seed Extract

Sambucus Nigra Fruit Extract

Camellia Oleifera Leaf

Chamomilla Recutita Flower Extract

Peucedanum Graveolens Extract

Allantoin

Adenosine

Hydrogenated Lecithin

Bisabolol

Polyquaternium-10

Xanthan Gum

Carbomer

Polysorbate 20

Sodium Bicarbonate

Sodium Hydroxide

Aminomethyl Propanol

Phenoxyethanol

Benzyl Alcohol

Water, Butylene Glycol, Glycolic Acid, Glycerin, Lactic Acid, Caprylic/Capric Triglyceride, Malic Acid, Tartaric Acid, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide Ng, Salicylic Acid, Glycyrrhiza Glabra Root, Camellia Sinensis Leaf Extract, Punica Granatum Extract, Lycium Barbarum Fruit Extract, Vitis Vinifera Seed Extract, Sambucus Nigra Fruit Extract, Camellia Oleifera Leaf, Chamomilla Recutita Flower Extract, Peucedanum Graveolens Extract, Allantoin, Adenosine, Hydrogenated Lecithin, Bisabolol, Polyquaternium-10, Xanthan Gum, Carbomer, Polysorbate 20, Sodium Bicarbonate, Sodium Hydroxide, Aminomethyl Propanol, Phenoxyethanol, Benzyl Alcohol

Paraffinum Liquidum

Glyceryl Stearate

Cetearyl Alcohol

Triethanolamine

Niacinamide

Cetyl Alcohol

Ammonium Lactate

Behentrimonium Methosulfate

PEG-100 Stearate

Zea Mays Oil

Ceramide NP

Ceramide AP

Ceramide EOP

Dimethicone

Methylparaben

Sodium Lauroyl Lactylate

Cholecalciferol

Cholesterol

Disodium EDTA

Tocopherol

Propylparaben

Hydrolyzed Hyaluronic Acid

Phytosphingosine

Water, Glycerin, Paraffinum Liquidum, Glyceryl Stearate, Cetearyl Alcohol, Triethanolamine, Salicylic Acid, Niacinamide, Cetyl Alcohol, Ammonium Lactate, Behentrimonium Methosulfate, PEG-100 Stearate, Zea Mays Oil, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Dimethicone, Methylparaben, Sodium Lauroyl Lactylate, Cholecalciferol, Cholesterol, Phenoxyethanol, Disodium EDTA, Tocopherol, Propylparaben, Hydrolyzed Hyaluronic Acid, Phytosphingosine, Xanthan Gum

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Salicylic Acid (also known as beta hydroxy acid or BHA) is a well-known ingredient for treating skin that struggles with acne and clogged pores. It exfoliates both the skin's surface and deep within the pores to help clear out buildup, control oil, and reduce inflammation.

Unlike AHAs (alpha hydroxy acids), salicylic acid is oil-soluble. This allows it to penetrate into pores which makes it especially effective for treating blackheads and preventing future breakouts.

Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.

Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.

It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.

While salicylic acid does not increase sun sensitivity, it’s still important to wear sunscreen daily to protect your skin.

If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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