Skin science article
Paula's Choice Resist Anti-Aging Clear Skin Hydrator Versus La Roche-Posay Effaclar Duo[+] Unifiant
Paula's Choice Resist Anti-Aging Clear Skin Hydrator Versus La Roche-Posay Effaclar Duo[+] Unifiant This anti-aging moisturizer is formulated around Sodium Ascorbyl Phosphate and Niacinamide to soften the look of wrinkles and balance excess oil. This acne mois
Paula's Choice Resist Anti-Aging Clear Skin Hydrator Versus La Roche-Posay Effaclar Duo[+] Unifiant
This anti-aging moisturizer is formulated around Sodium Ascorbyl Phosphate and Niacinamide to soften the look of wrinkles and balance excess oil.
This acne moisturizer is formulated around Niacinamide and Salicylic Acid to clear breakouts and balance excess oil.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Cyclopentasiloxane
Octyldodecyl Neopentanoate
Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer
Glycerin
Sodium Ascorbyl Phosphate
Cetyl Alcohol
Niacinamide
Dimethicone
Cetearyl Alcohol
Butylene Glycol
Glyceryl Stearate
PEG-100 Stearate
Adenosine
Epigallocatechin Gallate
Glucose Oxidase
Lactoperoxidase
Boerhavia Diffusa Root Extract
Cocos Nucifera Fruit Extract
Lactobacillus
Polysilicone-11
Sodium Chloride
Potassium Thiocyanate
Glucose
Xanthan Gum
Ceteareth-20
Decyl Glucoside
Citric Acid
Phenoxyethanol
Water, Cyclopentasiloxane, Octyldodecyl Neopentanoate, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Glycerin, Sodium Ascorbyl Phosphate, Cetyl Alcohol, Niacinamide, Dimethicone, Cetearyl Alcohol, Butylene Glycol, Glyceryl Stearate, PEG-100 Stearate, Adenosine, Epigallocatechin Gallate, Glucose Oxidase, Lactoperoxidase, Boerhavia Diffusa Root Extract, Cocos Nucifera Fruit Extract, Lactobacillus, Polysilicone-11, Sodium Chloride, Potassium Thiocyanate, Glucose, Xanthan Gum, Ceteareth-20, Decyl Glucoside, Citric Acid, Phenoxyethanol
Isocetyl Stearate
Isopropyl Lauroyl Sarcosinate
Ammonium Polyacryloyldimethyl Taurate
Methyl Methacrylate Crosspolymer
T-Butyl Alcohol
Sodium Hydroxide
Oleic Acid
Salicylic Acid
Silica Silylate
Poloxamer 338
Nylon-12
Polysorbate 80
Zinc PCA
Linoleic Acid
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Isohexadecane
2-Oleamido-1,3-Octadecanediol
Octanediol
Capryloyl Salicylic Acid
Caprylyl Glycol
Piroctone Olamine
Myristyl Myristate
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
Parfum
Sorbitan Oleate
Disodium EDTA
Potassium Cetyl Phosphate
BHT
Glyceryl Stearate Se
CI 77891
CI 77491
CI 77492
CI 77499
Mica
Water, Glycerin, Dimethicone, Isocetyl Stearate, Niacinamide, Isopropyl Lauroyl Sarcosinate, Ammonium Polyacryloyldimethyl Taurate, Methyl Methacrylate Crosspolymer, T-Butyl Alcohol, Sodium Hydroxide, Oleic Acid, Salicylic Acid, Silica Silylate, Poloxamer 338, Nylon-12, Polysorbate 80, Zinc PCA, Linoleic Acid, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Isohexadecane, 2-Oleamido-1,3-Octadecanediol, Octanediol, Capryloyl Salicylic Acid, Caprylyl Glycol, Piroctone Olamine, Myristyl Myristate, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Parfum, Sorbitan Oleate, Disodium EDTA, Potassium Cetyl Phosphate, BHT, Glyceryl Stearate Se, CI 77891, CI 77491, CI 77492, CI 77499, Mica
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!