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Skin science article

Paula's Choice Resist Ultra-Light Super Antioxidant Concentrate Serum Versus Paula's Choice Skin Balancing Super Antioxidant Concentrate Serum

Paula's Choice Resist Ultra-Light Super Antioxidant Concentrate Serum Versus Paula's Choice Skin Balancing Super Antioxidant Concentrate Serum This anti-aging serum is formulated around Resveratrol and Niacinamide to soften the look of wrinkles and calm rednes

Paula's Choice Resist Ultra-Light Super Antioxidant Concentrate Serum Versus Paula's Choice Skin Balancing Super Antioxidant Concentrate Serum

This anti-aging serum is formulated around Resveratrol and Niacinamide to soften the look of wrinkles and calm redness.

This anti-aging serum is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Cyclopentasiloxane

Butylene Glycol

Dimethicone

Glycerin

Polysorbate 20

Polysilicone-11

Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone

Hyaluronic Acid

Resveratrol

Niacinamide

Quercetin

Adenosine

Tetrahexyldecyl Ascorbate

Tocopherol

Phospholipids

Ubiquinone

Epigallocatechin Gallate

Sea Whip Extract

Bisabolol

Beta-Glucan

Phytic Acid

Xanthan Gum

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Sodium Hydroxide

Disodium EDTA

Ethylhexylglycerin

Phenoxyethanol

Water, Cyclopentasiloxane, Butylene Glycol, Dimethicone, Glycerin, Polysorbate 20, Polysilicone-11, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Hyaluronic Acid, Resveratrol, Niacinamide, Quercetin, Adenosine, Tetrahexyldecyl Ascorbate, Tocopherol, Phospholipids, Ubiquinone, Epigallocatechin Gallate, Sea Whip Extract, Bisabolol, Beta-Glucan, Phytic Acid, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol

Isododecane

Dimethicone Crosspolymer

Neopentyl Glycol Diheptanoate

Cyclohexasiloxane

Caprylic/Capric Triglyceride

Tocopheryl Acetate

Retinyl Palmitate

Retinol

Astaxanthin

Chamomilla Recutita Flower Extract

Camellia Sinensis Leaf Extract

Salix Alba Bark Extract

Vitis Vinifera Seed Extract

Ginkgo Biloba Leaf Extract

Calluna Vulgaris Flower Extract

Vaccinium Macrocarpon Fruit Extract

Rubus Idaeus Fruit Extract

Betula Alba Bark Extract

Glycine Soja Oil

Silica

Cyclopentasiloxane, Isododecane, Dimethicone Crosspolymer, Neopentyl Glycol Diheptanoate, Cyclohexasiloxane, Caprylic/Capric Triglyceride, Tocopheryl Acetate, Retinyl Palmitate, Retinol, Tetrahexyldecyl Ascorbate, Astaxanthin, Bisabolol, Chamomilla Recutita Flower Extract, Camellia Sinensis Leaf Extract, Salix Alba Bark Extract, Vitis Vinifera Seed Extract, Ginkgo Biloba Leaf Extract, Calluna Vulgaris Flower Extract, Vaccinium Macrocarpon Fruit Extract, Rubus Idaeus Fruit Extract, Betula Alba Bark Extract, Glycine Soja Oil, Silica, Phenoxyethanol

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient.

It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation.

A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.

In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.

You'll likely see use concentrations quite low, usually 0.1-0.2%.

Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.

Cyclopentasiloxane (D5) is a lightweight silicone that mostly acts as an emollient and solvent in cosmetics. Its the reason your products feel silky, fast-spreading, and non-greasy.

Since D5 is volatile, it does its thing and then evaporates off the skin quickly.

The safety profile of this ingredient is reassuring; the US CIR Expert Panel concluded D5 is safe as used in cosmetics and Health Canada concluded that D5 is not harmful to human health or the environment as currently used in cosmetics

There's a study that people mention about D5 in a rat study showing tumors. This study is related to long-term inhalation of high D5 levels.

Regulatory bodies have judged this study to be not applicable in topical skincare since skin absorption of D5 is very low and we're not really inhaling huge amounts of D5.

The only restriction for this ingredient is environmental. The European Chemicals Agency (ECHA) restricted D5 in wash-off cosmetics at or above 0.1% due to their persistence in water.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Tetrahexyldecyl Ascorbate (THD) is a stable and oil-soluble form of Vitamin C.

THD is special in that it has the ability to travel deeper into skin than traditional ascorbic acid while maintaining the same skin benefits (double win!).

Because it’s oil-soluble, THD dives deep into your skin’s fatty layers (think ceramides and cholesterol) to fight off the kind of free radicals that mess with your skin barrier. This makes it a great pair with water-based vitamin C (ascorbic acid) that mainly works on the surface.

Even at just 0.1%, THD is already showing great antioxidant activity. When used up to 2%, it helps keep your skin happy and calm, especially when it’s stressed from pollution or sun.

Want to fade dark spots or tackle hyperpigmentation? You’ll want 5% or more. Pairing it with brightening buddies like niacinamide or licorice root gives even better results. One study even used 30% THD with other brighteners and saw real results on stubborn discoloration, even in melasma-prone skin.

A note on THD: It’s has a slightly silky, oily texture and usually shows up colorless or pale yellow (though the exact shade can vary by supplier).

While you can sneak it into water-based formulas, it really shines when paired with silicones or oils, which help your skin soak it up better.

THD is pretty stable, but it’s still vulnerable to degradation like ascorbic acid. Too much light or heat (above 113°F / 45°C) can break it down over time. Go for dark and opaque packaging that keeps it safe and shady!

Read more about other types of Vitamin C:

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.
  4. 04What makes it special?
  5. 05OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.
  6. 06Here's what each tier does best:
  7. 07Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.
  8. 08Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.
  9. 09Cyclopentasiloxane (D5) is a lightweight silicone that mostly acts as an emollient and solvent in cosmetics. Its the reason your products feel silky, fast-spreading, and non-greasy.
  10. 10Since D5 is volatile, it does its thing and then evaporates off the skin quickly.
  11. 11The safety profile of this ingredient is reassuring; the US CIR Expert Panel concluded D5 is safe as used in cosmetics and Health Canada concluded that D5 is not harmful to human health or the environment as currently used in cosmetics
  12. 12There's a study that people mention about D5 in a rat study showing tumors. This study is related to long-term inhalation of high D5 levels.
  13. 13Regulatory bodies have judged this study to be not applicable in topical skincare since skin absorption of D5 is very low and we're not really inhaling huge amounts of D5.
  14. 14The only restriction for this ingredient is environmental. The European Chemicals Agency (ECHA) restricted D5 in wash-off cosmetics at or above 0.1% due to their persistence in water.
  15. 15Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
  16. 16It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
  17. 17On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
  18. 18Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
  19. 19You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
  20. 20Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Source · skinsort.com
02

Product index

Related product references

Product

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03

Comparison edit

Read side by side