Peach & Lily Overnight Star Night Cream Versus Peter Thomas Roth Peptide 21 Wrinkle Resist Serum

Peach & Lily Overnight Star Night Cream Versus Peter Thomas Roth Peptide 21 Wrinkle Resist Serum

This anti-aging night moisturizer is formulated around Squalane and Niacinamide to soften the look of wrinkles and hydrate skin.

This anti-aging serum is formulated around Tripeptide-10 Citrulline and Acetyl Octapeptide-3 to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Caprylic/Capric Triglyceride

Squalane

Glycerin

Cetearyl Alcohol

Jojoba Esters

Simmondsia Chinensis Seed Oil

Triethylhexanoin

Niacinamide

Macadamia Ternifolia Seed Oil

1,2-Hexanediol

Panax Ginseng Root Extract

Euterpe Oleracea Fruit Extract

Curcuma Longa Root Extract

Hydrolyzed Hyaluronic Acid

Centella Asiatica Extract

Coccinia Indica Fruit Extract

Corallina Officinalis Extract

Eclipta Prostrata Extract

Leuconostoc/Radish Root Ferment Filtrate

Collagen

Melia Azadirachta Flower Extract

Melia Azadirachta Leaf Extract

Moringa Oleifera Seed Oil

Oligopeptide-1

Allantoin

Lactobacillus Ferment

Panthenol

Sodium Acetylated Hyaluronate

Sodium Hyaluronate

Ocimum Sanctum Leaf Extract

Solanum Melongena Fruit Extract

Syringa Vulgaris Extract

Vaccinium Angustifolium Fruit Extract

Adenosine

Butylene Glycol

Butyrospermum Parkii Butter

Diethoxyethyl Succinate

Sorbitan Olivate

Citric Acid

Tocopherol

Glucose

Cetearyl Glucoside

Cetearyl Olivate

Coco-Caprylate/Caprate

Dipotassium Glycyrrhizate

Aloe Barbadensis Flower Extract

Hydroxyacetophenone

Trisodium Ethylenediamine Disuccinate

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Tromethamine

Xanthan Gum

Lavandula Angustifolia Oil

Water, Propanediol, Caprylic/Capric Triglyceride, Squalane, Glycerin, Cetearyl Alcohol, Jojoba Esters, Simmondsia Chinensis Seed Oil, Triethylhexanoin, Niacinamide, Macadamia Ternifolia Seed Oil, 1,2-Hexanediol, Panax Ginseng Root Extract, Euterpe Oleracea Fruit Extract, Curcuma Longa Root Extract, Hydrolyzed Hyaluronic Acid, Centella Asiatica Extract, Coccinia Indica Fruit Extract, Corallina Officinalis Extract, Eclipta Prostrata Extract, Leuconostoc/Radish Root Ferment Filtrate, Collagen, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Moringa Oleifera Seed Oil, Oligopeptide-1, Allantoin, Lactobacillus Ferment, Panthenol, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Ocimum Sanctum Leaf Extract, Solanum Melongena Fruit Extract, Syringa Vulgaris Extract, Vaccinium Angustifolium Fruit Extract, Adenosine, Butylene Glycol, Butyrospermum Parkii Butter, Diethoxyethyl Succinate, Sorbitan Olivate, Citric Acid, Tocopherol, Glucose, Cetearyl Glucoside, Cetearyl Olivate, Coco-Caprylate/Caprate, Dipotassium Glycyrrhizate, Aloe Barbadensis Flower Extract, Hydroxyacetophenone, Trisodium Ethylenediamine Disuccinate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Xanthan Gum, Lavandula Angustifolia Oil

Rosa Centifolia Flower Water

Isopropyl Myristate

Mannitol

Natto Gum

Tripeptide-10 Citrulline

Acetyl Octapeptide-3

Palmitoyl Hexapeptide-12

Acetyl Tetrapeptide-11

Acetyl Hexapeptide-8

Acetyl Hexapeptide-1

Palmitoyl Oligopeptide

Acetyl Tetrapeptide-9

Acetyl Tetrapeptide-2

Tripeptide-1

Palmitoyl Tetrapeptide-7

Hexapeptide-11

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Palmitoyl Tripeptide-5

Trifluoroacetyl Tripeptide-2

Palmitoyl Tripeptide-1

Sodium Polyglutamate

Tocopheryl Acetate

Retinyl Palmitate

Ascorbic Acid

Hydrolyzed Soy Protein

Hydrolyzed Wheat Protein

Lecithin

Pseudoalteromonas Ferment Extract

Acrylates Copolymer

Magnesium Chloride

Polysorbate 20

Dimethyl Isosorbide

PEG-8 Dimethicone

Disodium Phosphate

Carbomer

Dextran

Sodium Lactate

Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

Triethanolamine

Sodium Phosphate

Octyldodecanol

Silica

Sodium Propoxyhydroxypropyl Thiosulfate Silica

Sodium Hydroxide

Caprylyl Glycol

Potassium Sorbate

Sodium Benzoate

Phenoxyethanol

Water, Glycerin, Rosa Centifolia Flower Water, Isopropyl Myristate, Squalane, Mannitol, Butylene Glycol, Natto Gum, Tripeptide-10 Citrulline, Acetyl Octapeptide-3, Palmitoyl Hexapeptide-12, Acetyl Tetrapeptide-11, Acetyl Hexapeptide-8, Acetyl Hexapeptide-1, Palmitoyl Oligopeptide, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-2, Tripeptide-1, Palmitoyl Tetrapeptide-7, Hexapeptide-11, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tripeptide-5, Trifluoroacetyl Tripeptide-2, Palmitoyl Tripeptide-1, Sodium Polyglutamate, Sodium Hyaluronate, Tocopheryl Acetate, Retinyl Palmitate, Ascorbic Acid, Hydrolyzed Soy Protein, Hydrolyzed Wheat Protein, Lecithin, Pseudoalteromonas Ferment Extract, Acrylates Copolymer, Magnesium Chloride, Polysorbate 20, Dimethyl Isosorbide, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Leuconostoc/Radish Root Ferment Filtrate, PEG-8 Dimethicone, Disodium Phosphate, Carbomer, Dextran, Sodium Lactate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Xanthan Gum, Triethanolamine, Sodium Phosphate, Octyldodecanol, Silica, Sodium Propoxyhydroxypropyl Thiosulfate Silica, Sodium Hydroxide, Caprylyl Glycol, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.

As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.

It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.

A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Leuconostoc/Radish Root Ferment Filtrate is a natural preservative. It comes from fermenting radish roots with a bacteria called leuconostoc. The trade name for this ingredient is Leucidal.

Leuconostoc comes from lactic acid.

This ingredient has antimicrobial properties and helps prevent the growth of bacteria in a product.

Leuconostoc is used to make the traditional Korean side-dish, kimchi. It is also used to make sourdough bread (both incredibly yummy foods).

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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