Peach & Lily Peptide Pro Firming Moisturizer Versus Naturium Multi-Peptide Moisturizer

Peach & Lily Peptide Pro Firming Moisturizer Versus Naturium Multi-Peptide Moisturizer

This anti-aging moisturizer is formulated around Collagen Extract and Acetyl Hexapeptide-8 to soften the look of wrinkles and hydrate skin.

This anti-aging moisturizer is formulated around Palmitoyl Tripeptide-5 and Palmitoyl Tripeptide-1 to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Sorbitol

Glycerin

Cetearyl Alcohol

Butylene Glycol Dicaprylate/Dicaprate

1,2-Hexanediol

Caprylic/Capric Triglyceride

Hydrogenated Polydecene

C10-18 Triglycerides

Stearic Acid

Cetearyl Glucoside

Collagen Extract

Acetyl Hexapeptide-8

Dipeptide-2

Acetyl Tetrapeptide-5

Sh-Oligopeptide-1

Copper Tripeptide-1

Tripeptide-1

Palmitoyl Tripeptide-5

Palmitoyl Tripeptide-1

Nonapeptide-1

Hexapeptide-9

Palmitoyl Pentapeptide-4

Sh-Polypeptide-1

Serine

Methionine

Cysteine

Arginine

Tremella Fuciformis Extract

Phytosteryl/Octyldodecyl Lauroyl Glutamate

Polyglutamic Acid

Polyglyceryl-3 Methylglucose Distearate

Hydrolyzed Sodium Hyaluronate

Hydrolyzed Hyaluronic Acid

Hyaluronic Acid

Squalane

Sodium Hyaluronate

Sodium Hyaluronate Crosspolymer

Glyceryl Glucoside

Saccharomyces/Rice Ferment Filtrate

Prunus Mume Fruit Extract

Curcuma Longa Root Extract

Corallina Officinalis Extract

Panax Ginseng Callus Culture Extract

Solanum Melongena Fruit Extract

Prunus Armeniaca Fruit Extract

Aloe Barbadensis Leaf Extract

Ocimum Sanctum Leaf Extract

Adenosine

Tocopherol

Sorbitan Stearate

Carbomer

Sodium Polyacryloyldimethyl Taurate

Origanum Majorana Leaf Extract

Melia Azadirachta Leaf Extract

Melia Azadirachta Flower Extract

Aloe Barbadensis Flower Extract

Phellinus Linteus Extract

3-O-Ethyl Ascorbic Acid

Glucose

Ethylhexylglycerin

Coccinia Indica Fruit Extract

Pentylene Glycol

Caprylyl Glycol

Tropolone

Citrus Aurantium Bergamia Fruit Oil

Water, Butylene Glycol, Sorbitol, Glycerin, Cetearyl Alcohol, Butylene Glycol Dicaprylate/Dicaprate, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Hydrogenated Polydecene, C10-18 Triglycerides, Stearic Acid, Cetearyl Glucoside, Collagen Extract, Acetyl Hexapeptide-8, Dipeptide-2, Acetyl Tetrapeptide-5, Sh-Oligopeptide-1, Copper Tripeptide-1, Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Tripeptide-1, Nonapeptide-1, Hexapeptide-9, Palmitoyl Pentapeptide-4, Sh-Polypeptide-1, Serine, Methionine, Cysteine, Arginine, Tremella Fuciformis Extract, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Polyglutamic Acid, Polyglyceryl-3 Methylglucose Distearate, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Squalane, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Glyceryl Glucoside, Saccharomyces/Rice Ferment Filtrate, Prunus Mume Fruit Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Panax Ginseng Callus Culture Extract, Solanum Melongena Fruit Extract, Prunus Armeniaca Fruit Extract, Aloe Barbadensis Leaf Extract, Ocimum Sanctum Leaf Extract, Adenosine, Tocopherol, Sorbitan Stearate, Carbomer, Sodium Polyacryloyldimethyl Taurate, Origanum Majorana Leaf Extract, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Aloe Barbadensis Flower Extract, Phellinus Linteus Extract, 3-O-Ethyl Ascorbic Acid, Glucose, Ethylhexylglycerin, Coccinia Indica Fruit Extract, Pentylene Glycol, Caprylyl Glycol, Tropolone, Citrus Aurantium Bergamia Fruit Oil

Dimethicone

Simmondsia Chinensis Seed Oil

Glyceryl Stearate

Cetyl Alcohol

Niacinamide

Stearyl Alcohol

Pantolactone

Palmitoyl Tetrapeptide-7

Hydrolyzed Plukenetia Volubilis Seed Extract

Dunaliella Salina Extract

Panthenol

Caryodendron Orinocense Seed Oil

Honokiol

Magnolol

Palmitic Acid

Sorbitan Oleate

Aluminum Starch Octenylsuccinate

Hydroxyacetophenone

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

Polyglyceryl-6 Laurate

Boron Nitride

Polyglyceryl-10 Oleate

Isohexadecane

Chlorphenesin

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Tocopheryl Acetate

Polysorbate 80

Sorbitan Palmitate

Sodium Hydroxide

Sodium Benzoate

Sodium Lactate

Phenoxyethanol

Polysorbate 20

Citric Acid

Potassium Sorbate

Water, Glycerin, Dimethicone, Simmondsia Chinensis Seed Oil, Squalane, Glyceryl Stearate, Cetyl Alcohol, Niacinamide, Stearyl Alcohol, Palmitoyl Tripeptide-5, Pantolactone, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Hydrolyzed Plukenetia Volubilis Seed Extract, Dunaliella Salina Extract, Sodium Hyaluronate, 3-O-Ethyl Ascorbic Acid, Panthenol, Caryodendron Orinocense Seed Oil, Honokiol, Magnolol, Palmitic Acid, Sorbitan Oleate, Aluminum Starch Octenylsuccinate, Hydroxyacetophenone, Stearic Acid, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Polyglyceryl-6 Laurate, 1,2-Hexanediol, Boron Nitride, Caprylyl Glycol, Polyglyceryl-10 Oleate, Isohexadecane, Butylene Glycol, Chlorphenesin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopheryl Acetate, Polysorbate 80, Sorbitan Palmitate, Sodium Hydroxide, Sodium Benzoate, Carbomer, Sodium Lactate, Phenoxyethanol, Polysorbate 20, Citric Acid, Ethylhexylglycerin, Potassium Sorbate

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

3-O-Ethyl Ascorbic Acid is one of the most popular "stable" vitamin C derivatives in skincare.

Plain ascorbic acid is fantastic but notoriously fragile; it browns, oxidizes, and loses potency fast. So attaching an ethyl group to the third carbon of the molecule gives it some cool perks:

In a formula, it does the 3 classic vitamin C jobs: it acts as an antioxidant, helps brighten skin tone by inhibiting tyrosinase, and supports collagen.

The evidence is reasonably solid for a cosmetic ingredient; Liao and colleagues (2018) showed it's significantly more stable than ascorbic acid while still being effective.

A 2021 study by Zerbinati and colleagues tested a serum with 30% 3-O-ethyl-l-ascorbic acid and 1% lactic acid significantly increased collagen production, reduced UVB-induced DNA damage, and decreased melanin on a reconstructed pigmented skin model.

Typical real world usage sits around 0.5-5% (and 1-2% is common for daily serums).

Amounts up to 30% have been shown to be non-irritating on human skin samples, but two isolated cases reported allergic contact dermatitis so a patch test is sensible if you have reactive skin.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.

That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.

Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.

In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.

Human clinical data is promising, but modest:

A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.

A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.

You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.

Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.

Palmitoyl Tripeptide-5 is a synthetic signal lipopeptide. This just means it is a three amino acid chain bolted onto a palmitic acid tail so it can slip through the skin's lipid barrier.

This peptide has a "build more, lose less" approach.

It's designed to mimic the collagen-stimulating activity in your skin by copying a snippet of one of your skin's own matrix proteins. This nudges fibroblasts into making more collagen while inhibiting the enzyme that breaks down skin protein.

The manufacturer's in vivo study of 45 volunteers found 1% and 2.5% reduced the appearance of wrinkles by 7% and 12% respectively, after using it twice daily for 84 days.

This is in the expected range for peptides; they're slow and cumulative actives and not overnight fixers.

Typical use levels range from 1-3% and this ingredient gets along with pretty much everything.

On the fungal acne front: Although palmitic acid sits in the chain length that Malassezia can feed on, this ingredient has it locked in an amine bond. This makes it hard for Malassezia to access as a source of food, and therefore fungal acne safe.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.

In cosmetics, it is a multitasker:

Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.

Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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