Peter Thomas Roth Peptide 21 Wrinkle Resist Moisturizer Versus Clarins Extra Firming Energy

Peter Thomas Roth Peptide 21 Wrinkle Resist Moisturizer Versus Clarins Extra Firming Energy

This anti-aging moisturizer is formulated around Hexapeptide-11 and Dipeptide Diaminobutyroyl Benzylamide Diacetate to soften the look of wrinkles.

This day moisturizer is formulated around Avena Sativa Kernel Extract and Lycium Barbarum Fruit Extract to hydrate and support the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Dimethicone

Olive Oil Decyl Esters

Glycereth-26

Squalane

Butylene Glycol

Behenyl Alcohol

Polysilicone-11

Batyl Alcohol

Simmondsia Chinensis Seed Oil

Hexapeptide-11

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Palmitoyl Tripeptide-5

Tripeptide-10 Citrulline

Acetyl Hexapeptide-1

Acetyl Tetrapeptide-11

Acetyl Hexapeptide-8

Palmitoyl Hexapeptide-12

Acetyl Tetrapeptide-9

Palmitoyl Tetrapeptide-7

Acetyl Tetrapeptide-2

Acetyl Octapeptide-3

Palmitoyl Hexapeptide-19

Trifluoroacetyl Tripeptide-2

Tripeptide-1

Palmitoyl Oligopeptide

Palmitoyl Tripeptide-1

Potassium Hydrolyzed Polygamma-Glutamate

Sodium Polyglutamate

Squalene

Mica

Sodium Hyaluronate

Sorbic Acid

Tocopherol

Cereus Grandiflorus Flower Extract

Pseudoalteromonas Ferment Extract

Leuconostoc/Radish Root Ferment Filtrate

Magnesium Chloride

Phenoxyethanol

Cetyl Alcohol

Stearyl Alcohol

Trehalose

Glyceryl Stearate

Silanetriol Trehalose Ether

Mannitol

Phytosterols

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Caprylic/Capric Triglyceride

Hydrogenated Lecithin

Polyglyceryl-10 Myristate

Polysorbate 20

Dimethyl Isosorbide

Sodium Benzoate

Potassium Sorbate

Caprylyl Glycol

Sodium Hydroxide

Laureth-12

Hydrolyzed Wheat Protein

Lecithin

Disodium Phosphate

Hydrolyzed Soy Protein

Carbomer

Dextran

Ethylhexylglycerin

Sodium Lactate

Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

Sodium Phosphate

Xanthan Gum

Triethanolamine

Acrylates Copolymer

Water, Glycerin, Dimethicone, Olive Oil Decyl Esters, Glycereth-26, Squalane, Butylene Glycol, Behenyl Alcohol, Polysilicone-11, Batyl Alcohol, Simmondsia Chinensis Seed Oil, Hexapeptide-11, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tripeptide-5, Tripeptide-10 Citrulline, Acetyl Hexapeptide-1, Acetyl Tetrapeptide-11, Acetyl Hexapeptide-8, Palmitoyl Hexapeptide-12, Acetyl Tetrapeptide-9, Palmitoyl Tetrapeptide-7, Acetyl Tetrapeptide-2, Acetyl Octapeptide-3, Palmitoyl Hexapeptide-19, Trifluoroacetyl Tripeptide-2, Tripeptide-1, Palmitoyl Oligopeptide, Palmitoyl Tripeptide-1, Potassium Hydrolyzed Polygamma-Glutamate, Sodium Polyglutamate, Squalene, Mica, Sodium Hyaluronate, Sorbic Acid, Tocopherol, Cereus Grandiflorus Flower Extract, Pseudoalteromonas Ferment Extract, Leuconostoc/Radish Root Ferment Filtrate, Magnesium Chloride, Phenoxyethanol, Cetyl Alcohol, Stearyl Alcohol, Trehalose, Glyceryl Stearate, Silanetriol Trehalose Ether, Mannitol, Phytosterols, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylic/Capric Triglyceride, Hydrogenated Lecithin, Polyglyceryl-10 Myristate, Polysorbate 20, Dimethyl Isosorbide, Sodium Benzoate, Potassium Sorbate, Caprylyl Glycol, Sodium Hydroxide, Laureth-12, Hydrolyzed Wheat Protein, Lecithin, Disodium Phosphate, Hydrolyzed Soy Protein, Carbomer, Dextran, Ethylhexylglycerin, Sodium Lactate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Sodium Phosphate, Xanthan Gum, Triethanolamine, Acrylates Copolymer

Prunus Armeniaca Kernel Oil

Butyrospermum Parkii Butter

CI 77891

Phenyl Trimethicone

Pentaerythrityl Tetraethylhexanoate

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Synthetic Fluorphlogopite

Pentaerythrityl Distearate

Pentylene Glycol

Polyacrylate Crosspolymer-6

Parfum

Anigozanthos Flavidus Extract

Avena Sativa Kernel Extract

Disodium EDTA

Tocopheryl Acetate

Citric Acid

Dimethiconol

Betaine

Sorbitol

Capsicum Annuum Fruit Meristem Cell

Tin Oxide

T-Butyl Alcohol

Marrubium Vulgare Extract

Lycium Barbarum Fruit Extract

Kalanchoe Pinnata Leaf Extract

Balanites Roxburghii Seed Oil

Mitracarpus Scaber Extract

Malpighia Emarginata Seed Extract

Phenethyl Alcohol

CI 14700

Furcellaria Lumbricalis Extract

Helianthus Annuus Seed Oil

Lapsana Communis Flower/Leaf/Stem Extract

Maris Sal

Coumarin

Rosmarinus Officinalis Leaf Extract

Water, Glycerin, Prunus Armeniaca Kernel Oil, Dimethicone, Caprylic/Capric Triglyceride, Butyrospermum Parkii Butter, CI 77891, Phenyl Trimethicone, Pentaerythrityl Tetraethylhexanoate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Synthetic Fluorphlogopite, Pentaerythrityl Distearate, Pentylene Glycol, Polyglyceryl-10 Myristate, Polyacrylate Crosspolymer-6, Parfum, Butylene Glycol, Sodium Benzoate, Anigozanthos Flavidus Extract, Avena Sativa Kernel Extract, Disodium EDTA, Tocopheryl Acetate, Citric Acid, Sodium Hyaluronate, Dimethiconol, Betaine, Sorbitol, Capsicum Annuum Fruit Meristem Cell, Tin Oxide, T-Butyl Alcohol, Marrubium Vulgare Extract, Lycium Barbarum Fruit Extract, Kalanchoe Pinnata Leaf Extract, Balanites Roxburghii Seed Oil, Mitracarpus Scaber Extract, Malpighia Emarginata Seed Extract, Phenethyl Alcohol, CI 14700, Furcellaria Lumbricalis Extract, Helianthus Annuus Seed Oil, Potassium Sorbate, Tocopherol, Lapsana Communis Flower/Leaf/Stem Extract, Maris Sal, Coumarin, Rosmarinus Officinalis Leaf Extract

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Polyglyceryl-10 Myristate is a nonionic emulsifier and skin conditioner made from Polyglycerin-10 and Myristic Acid.

As a skin conditioning agent, this ingredient leaves skin feeling soft without a greasy finish. As an emulsifier, it helps stabilize oil-in-water emulsions.

You'll likely see this ingredient in "clean" formulations because it's considered a natural alternative to PEGs.

Patch testing at concentration 0.1-1% showed no reactions and this ingredient is considered to be well-tolerated across skin types.

Due to its myristic acid base, this ingredient may not be fungal acne safe.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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