Peter Thomas Roth Peptide Skinjection Fill + Fix Under-Eye Cream Versus MediCube PDRN Pink Peptide Eye Cream

Peter Thomas Roth Peptide Skinjection Fill + Fix Under-Eye Cream Versus MediCube PDRN Pink Peptide Eye Cream

This anti-aging eye moisturizer is formulated around Caffeine and Sodium Hyaluronate to soften the look of wrinkles and hydrate skin.

This anti-aging eye moisturizer is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dimethicone

Butylene Glycol

Cetyl PEG/PPG-10/1 Dimethicone

Glycerin

Polysilicone-11

Bellis Perennis Flower Extract

PEG/PPG-18/18 Dimethicone

Sh-Pentapeptide-5

Hieracium Pilosella Extract

Caffeine

Sodium Hyaluronate

Potassium Glutathione Isomerized Linoleate

Glucomannan

Sodium Chloride

Silica

Silica Silylate

Sodium Citrate

Citric Acid

Trihydroxystearin

Ethylhexyl Palmitate

Lauryl Glucoside

Sodium Benzoate

Ethylhexylglycerin

Potassium Chloride

Tetrasodium Glutamate Diacetate

Propylene Glycol

Decyl Glucoside

Trisiloxane

Potassium Sorbate

Sodium Dehydroacetate

1,2-Hexanediol

Mica

Triethoxycaprylylsilane

Titanium Dioxide

Iron Oxides

CI 77492

CI 77491

Phenoxyethanol

Water, Dimethicone, Butylene Glycol, Cetyl PEG/PPG-10/1 Dimethicone, Glycerin, Polysilicone-11, Bellis Perennis Flower Extract, PEG/PPG-18/18 Dimethicone, Sh-Pentapeptide-5, Hieracium Pilosella Extract, Caffeine, Sodium Hyaluronate, Potassium Glutathione Isomerized Linoleate, Glucomannan, Sodium Chloride, Silica, Silica Silylate, Sodium Citrate, Citric Acid, Trihydroxystearin, Ethylhexyl Palmitate, Lauryl Glucoside, Sodium Benzoate, Ethylhexylglycerin, Potassium Chloride, Tetrasodium Glutamate Diacetate, Propylene Glycol, Decyl Glucoside, Trisiloxane, Potassium Sorbate, Sodium Dehydroacetate, 1,2-Hexanediol, Mica, Triethoxycaprylylsilane, Titanium Dioxide, Iron Oxides, CI 77492, CI 77491, Phenoxyethanol

Dipropylene Glycol

Niacinamide

Caprylic/Capric Triglyceride

Pentaerythrityl Tetraethylhexanoate

Cetearyl Alcohol

Glycereth-26

Butylene Glycol Dicaprylate/Dicaprate

Bis-Behenyl/Isostearyl/Phytosteryl Dimer Dilinoleyl Dimer Dilinoleate

Cetearyl Olivate

Sorbitan Olivate

Propylene Glycol Dibenzoate

Pullulan

Glyceryl Stearate

Vinyldimethicone

Hydroxyacetophenone

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Hydrogenated Lecithin

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Sodium DNA

Polyisobutene

Propanediol

Melia Azadirachta Leaf Extract

Adenosine

Melia Azadirachta Flower Extract

Curcuma Longa Root Extract

Sorbitan Isostearate

Sorbitan Oleate

Caprylyl/Capryl Glucoside

Fragaria Chiloensis Fruit Extract

Hedera Helix Leaf/Stem Extract

Cyanocobalamin

Citrus Nobilis Peel Extract

Retinol

Ocimum Sanctum Leaf Extract

Lespedeza Capitata Leaf/Stem Extract

Corallina Officinalis Extract

Coffea Arabica Seed Extract

Hydrolyzed Extensin

Hydrolyzed Hyaluronic Acid

Copper Tripeptide-1

Sodium Acetylated Hyaluronate

Acetyl Hexapeptide-8

Palmitoyl Pentapeptide-4

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

Water, Glycerin, Dipropylene Glycol, Niacinamide, Caprylic/Capric Triglyceride, Pentaerythrityl Tetraethylhexanoate, Cetearyl Alcohol, Glycereth-26, Butylene Glycol Dicaprylate/Dicaprate, Bis-Behenyl/Isostearyl/Phytosteryl Dimer Dilinoleyl Dimer Dilinoleate, Cetearyl Olivate, Sorbitan Olivate, Propylene Glycol Dibenzoate, Pullulan, 1,2-Hexanediol, Glyceryl Stearate, Vinyldimethicone, Hydroxyacetophenone, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrogenated Lecithin, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium DNA, Polyisobutene, Butylene Glycol, Ethylhexylglycerin, Propanediol, Melia Azadirachta Leaf Extract, Adenosine, Melia Azadirachta Flower Extract, Curcuma Longa Root Extract, Sorbitan Isostearate, Sorbitan Oleate, Caprylyl/Capryl Glucoside, Fragaria Chiloensis Fruit Extract, Hedera Helix Leaf/Stem Extract, Cyanocobalamin, Citrus Nobilis Peel Extract, Retinol, Ocimum Sanctum Leaf Extract, Lespedeza Capitata Leaf/Stem Extract, Corallina Officinalis Extract, Sodium Hyaluronate, Caffeine, Coffea Arabica Seed Extract, Hydrolyzed Extensin, Hydrolyzed Hyaluronic Acid, Copper Tripeptide-1, Sodium Acetylated Hyaluronate, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.

As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.

Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.

You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.

Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.

Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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