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Skin science article

Peter Thomas Roth Water Drench Hyaluronic Cloud Cream Hydrating Moisturizer Versus Peter Thomas Roth Peptide Skinjection Moisture Infusion Cream

Peter Thomas Roth Water Drench Hyaluronic Cloud Cream Hydrating Moisturizer Versus Peter Thomas Roth Peptide Skinjection Moisture Infusion Cream This barrier-repair moisturizer is formulated around Sodium Hyaluronate and Ceramide NP to strengthen the skin barr

Peter Thomas Roth Water Drench Hyaluronic Cloud Cream Hydrating Moisturizer Versus Peter Thomas Roth Peptide Skinjection Moisture Infusion Cream

This barrier-repair moisturizer is formulated around Sodium Hyaluronate and Ceramide NP to strengthen the skin barrier and hydrate skin.

This anti-aging moisturizer is formulated around Squalane and Hexapeptide-11 to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Cyclopentasiloxane

Dipropylene Glycol

Dimethicone

Cyclohexasiloxane

Yeast Extract

Sodium Hyaluronate

Ceramide EOP

Ceramide Eos

Ceramide AP

Ceramide NP

Ceramide Ns

Sambucus Nigra Fruit Extract

Hydrolyzed Silk

Sodium PCA

Tocopherol

Ascorbyl Palmitate

Caprooyl Phytosphingosine

Caprooyl Sphingosine

Saccharide Isomerate

Saccharomyces/Magnesium Ferment

Saccharomyces/Iron Ferment

Saccharomyces/Copper Ferment

Saccharomyces/Silicon Ferment

Saccharomyces/Zinc Ferment

Olea Europaea Leaf Extract

Methyl Gluceth-20

Ethylhexylglycerin

Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone

Cholesterol

Sodium Chloride

Sodium Citrate

Citric Acid

Behenic Acid

Propylene Glycol

Ceteareth-25

Butylene Glycol

Dimethicone/PEG-10/15 Crosspolymer

Cetyl Alcohol

Disodium EDTA

Sodium Benzoate

Potassium Sorbate

Phenoxyethanol

Mica

Water, Glycerin, Cyclopentasiloxane, Dipropylene Glycol, Dimethicone, Cyclohexasiloxane, Yeast Extract, Sodium Hyaluronate, Ceramide EOP, Ceramide Eos, Ceramide AP, Ceramide NP, Ceramide Ns, Sambucus Nigra Fruit Extract, Hydrolyzed Silk, Sodium PCA, Tocopherol, Ascorbyl Palmitate, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Saccharide Isomerate, Saccharomyces/Magnesium Ferment, Saccharomyces/Iron Ferment, Saccharomyces/Copper Ferment, Saccharomyces/Silicon Ferment, Saccharomyces/Zinc Ferment, Olea Europaea Leaf Extract, Methyl Gluceth-20, Ethylhexylglycerin, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Cholesterol, Sodium Chloride, Sodium Citrate, Citric Acid, Behenic Acid, Propylene Glycol, Ceteareth-25, Butylene Glycol, Dimethicone/PEG-10/15 Crosspolymer, Cetyl Alcohol, Disodium EDTA, Sodium Benzoate, Potassium Sorbate, Phenoxyethanol, Mica

Olive Oil Decyl Esters

Glycereth-26

Squalane

Behenyl Alcohol

Polysilicone-11

Batyl Alcohol

Simmondsia Chinensis Seed Oil

Hexapeptide-11

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Palmitoyl Tripeptide-5

Tripeptide-10 Citrulline

Acetyl Hexapeptide-1

Acetyl Tetrapeptide-11

Acetyl Hexapeptide-8

Palmitoyl Hexapeptide-12

Acetyl Tetrapeptide-9

Palmitoyl Tetrapeptide-7

Acetyl Tetrapeptide-2

Acetyl Octapeptide-3

Palmitoyl Hexapeptide-19

Trifluoroacetyl Tripeptide-2

Tripeptide-1

Palmitoyl Oligopeptide

Palmitoyl Tripeptide-1

Natto Gum

Sodium Polyglutamate

Squalene

Sorbic Acid

Cereus Grandiflorus Flower Extract

Pseudoalteromonas Ferment Extract

Leuconostoc/Radish Root Ferment Filtrate

Magnesium Chloride

Stearyl Alcohol

Trehalose

Glyceryl Stearate

Silanetriol Trehalose Ether

Mannitol

Phytosterols

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Caprylic/Capric Triglyceride

Hydrogenated Lecithin

Polyglyceryl-10 Myristate

Polysorbate 20

Dimethyl Isosorbide

Caprylyl Glycol

Sodium Hydroxide

Laureth-12

Hydrolyzed Wheat Protein

Lecithin

Disodium Phosphate

Hydrolyzed Soy Protein

Carbomer

Dextran

Sodium Lactate

Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

Sodium Phosphate

Xanthan Gum

Triethanolamine

Acrylates Copolymer

Water, Glycerin, Dimethicone, Olive Oil Decyl Esters, Glycereth-26, Squalane, Butylene Glycol, Behenyl Alcohol, Polysilicone-11, Batyl Alcohol, Simmondsia Chinensis Seed Oil, Hexapeptide-11, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tripeptide-5, Tripeptide-10 Citrulline, Acetyl Hexapeptide-1, Acetyl Tetrapeptide-11, Acetyl Hexapeptide-8, Palmitoyl Hexapeptide-12, Acetyl Tetrapeptide-9, Palmitoyl Tetrapeptide-7, Acetyl Tetrapeptide-2, Acetyl Octapeptide-3, Palmitoyl Hexapeptide-19, Trifluoroacetyl Tripeptide-2, Tripeptide-1, Palmitoyl Oligopeptide, Palmitoyl Tripeptide-1, Natto Gum, Sodium Polyglutamate, Squalene, Mica, Sodium Hyaluronate, Sorbic Acid, Tocopherol, Cereus Grandiflorus Flower Extract, Pseudoalteromonas Ferment Extract, Leuconostoc/Radish Root Ferment Filtrate, Magnesium Chloride, Phenoxyethanol, Cetyl Alcohol, Stearyl Alcohol, Trehalose, Glyceryl Stearate, Silanetriol Trehalose Ether, Mannitol, Phytosterols, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylic/Capric Triglyceride, Hydrogenated Lecithin, Polyglyceryl-10 Myristate, Polysorbate 20, Dimethyl Isosorbide, Sodium Benzoate, Potassium Sorbate, Caprylyl Glycol, Sodium Hydroxide, Laureth-12, Hydrolyzed Wheat Protein, Lecithin, Disodium Phosphate, Hydrolyzed Soy Protein, Carbomer, Dextran, Ethylhexylglycerin, Sodium Lactate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Sodium Phosphate, Xanthan Gum, Triethanolamine, Acrylates Copolymer

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

Its main roles are:

Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.

The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Mica is a naturally occurring mineral used to add shimmer and color in cosmetics. It can also help improve the texture of a product or give it an opaque, white/silver color.

Serecite is the name for very fine but ragged grains of mica.

This ingredient is often coated with metal oxides like titanium dioxide. Trace amounts of heavy metals may be found in mica, but these metals are not harmful in our personal products.

Mica has been used since prehistoric times throughout the world. Ancient Egyptian, Indian, Greek, Roman, Aztec, and Chinese civilizations have used mica.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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