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Skin science article

Proactiv Renewing Cleanser Versus PCA Skin BPO 5% Cleanser

Proactiv Renewing Cleanser Versus PCA Skin BPO 5% Cleanser This benzoyl peroxide cream cleanser is formulated around Benzoyl Peroxide to clear breakouts and help reduce acne-causing bacteria. This benzoyl peroxide foaming cleanser is formulated around Benzoyl

Proactiv Renewing Cleanser Versus PCA Skin BPO 5% Cleanser

This benzoyl peroxide cream cleanser is formulated around Benzoyl Peroxide to clear breakouts and help reduce acne-causing bacteria.

This benzoyl peroxide foaming cleanser is formulated around Benzoyl Peroxide to clear breakouts and help reduce acne-causing bacteria.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Benzoyl Peroxide 2.5%

Water

Magnesium Aluminum Silicate

Glyceryl Stearate

PEG-100 Stearate

Sorbitol

Dimethyl Isosorbide

Disodium PEG-12 Dimethicone Sulfosuccinate

Tridecyl Stearate

Neopentyl Glycol Dicaprylate/Dicaprate

Paraffin

Cetyl Esters

Anthemis Nobilis Flower Extract

Tridecyl Trimellitate

Trisodium Sulfosuccinate

PEG-12 Dimethicone

Sodium Sulfate

Sodium Hyaluronate

Propylene Glycol

Sodium PCA

Xanthan Gum

Phenoxyethanol

Imidazolidinyl Urea

Methylparaben

Propylparaben

Parfum

Benzoyl Peroxide 2.5%, Water, Magnesium Aluminum Silicate, Glyceryl Stearate, PEG-100 Stearate, Sorbitol, Dimethyl Isosorbide, Disodium PEG-12 Dimethicone Sulfosuccinate, Tridecyl Stearate, Neopentyl Glycol Dicaprylate/Dicaprate, Paraffin, Cetyl Esters, Anthemis Nobilis Flower Extract, Tridecyl Trimellitate, Trisodium Sulfosuccinate, PEG-12 Dimethicone, Sodium Sulfate, Sodium Hyaluronate, Propylene Glycol, Sodium PCA, Xanthan Gum, Phenoxyethanol, Imidazolidinyl Urea, Methylparaben, Propylparaben, Parfum

Benzoyl Peroxide 5%

Gluconolactone

Sodium C14-16 Olefin Sulfonate

Aminomethyl Propanol

Glycerin

Cocamidopropyl Betaine

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Polyacrylate-13

Citrus Grandis Peel Oil

Polyisobutene

Caprylyl Glycol

Ethylhexylglycerin

Hexylene Glycol

Allantoin

Simmondsia Chinensis Seed Oil

Tocopheryl Acetate

Triticum Vulgare Germ Oil

Aloe Barbadensis Leaf Juice

Panthenol

Polysorbate 20

Butylene Glycol

Phytic Acid

Algae Extract

Arnica Montana Flower Extract

Cucumis Sativus Fruit Extract

Vitis Vinifera Seed Extract

Benzoyl Peroxide 5%, Water, Gluconolactone, Sodium C14-16 Olefin Sulfonate, Aminomethyl Propanol, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Phenoxyethanol, Polyacrylate-13, Citrus Grandis Peel Oil, Polyisobutene, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Allantoin, Simmondsia Chinensis Seed Oil, Tocopheryl Acetate, Triticum Vulgare Germ Oil, Aloe Barbadensis Leaf Juice, Panthenol, Sodium PCA, Polysorbate 20, Butylene Glycol, Phytic Acid, Algae Extract, Anthemis Nobilis Flower Extract, Arnica Montana Flower Extract, Cucumis Sativus Fruit Extract, Vitis Vinifera Seed Extract

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Anthemis Nobilis Flower Extract is from the Roman Chamomile flower. It helps soothe the skin and contains antioxidants.

Benzoyl Peroxide (BPO) is one of the most studied and widely used acne-fighting ingredients on the market for over five decades.

It works by releasing oxygen into your pores to kill Cutibacterium acne, or the bacteria closely linked to acne breakouts. This bacteria has a hard time surviving in an oxygen-rich environment.

On top of that, BPO has keratolytic properties to help shed dead skin cells and keep pores from getting clogged.

One of the coolest things about BPO is that bacteria do not develop resistance to it the way they can with antibiotics. That's why dermatologists recommend pairing it with topical antibiotics to keep resistance at bay.

BPO is usually available in 2.5%, 5%, and 10% concentrations. Research has shown that 2.5% tends to be just as effective as the higher strengths while being more gentle on the skin.

The FDA has classified BPO as a safe and effective acne treatment. You'll be able to find this ingredient in over-the-counter products in many countries.

Just so you know, BPO is a known mild irritant. It's common to see dryness, peeling, and some redness when you first start using it. This usually goes away as your skin adjusts.

A very small number of people might develop allergic contact dermatitis from it as patch test studies show positive reactions in about 1-5% of patients.

Once BPO is absorbed into the skin, our bodies turn it into benzoic acid and quickly exits in urine. It's also worth noting that BPO will bleach fabrics and hair, so watch your towels and pillowcases!

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium PCA (the salt of PCA) is one of the most well-established humectants in skincare.

Why is it so special? Your skin already makes it naturally; it's a natural component of your skin's Natural Moisturizing Factor (NMF), or the mix of water-binding compounds inside your skin cells that keeps things soft and hydrated.

As a cosmetic ingredient, it grabs water and holds it in the upper layers of skin to smooth roughness and ease dehydration.

There's some clinical support for the NMF approach with a study showing that a cream built to mimic the skin's NMF significantly boosted hydration.

Safety-wise, this ingredient non-irritating, non-comedogenic, and non-phototoxic in testing, with minimal skin absorption.

It also works really well with other hydrators like glycerin or hyaluronic acid, and typical usage is somewhere between 0.2-4%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
  4. 04Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
  5. 05Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
  6. 06Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  7. 07Topically, glycerin does several things at once:
  8. 08Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  9. 09Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  10. 10This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  11. 11Just know very high concentrations (>40%) can feel tacky in low humidity.
  12. 12Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  13. 13Kaolin is a clay. It is used for oil control and to help minimize pores. Like other clays, kaolin has the ability to absorb excess sebum or oil. This can help clean out pores and mattify the skin.
  14. 14Some types of kaolin may have exfoliating properties. When water is added to kaolin, it becomes a paste with small abrasive particles.
  15. 15Most kaolin is a white color, but may be pink/orange/red depending on where it comes from.
  16. 16The name 'kaolin' comes from a Chinese village named 'Gaoling'. Kaolin clay comes from rocks rich in kaolinite. Kaolinite, the mineral, has a silicate layered structure. Kaolinite is formed from chemical weathering of aluminum siilicate minerals.
  17. 17Besides skincare, kaolin is commonly used to make glossy paper, in ceramics, toothpaste, and as medicine to soothe stomach issues.
  18. 18Magnesium Aluminum Silicate is a type of silica. It comes from naturally occuring minerals such as silicate ores and clay.
  19. 19Magnesium aluminum silicate is used for enhancing texture and as an absorbent. Due to its large molecular size, it is unable to be absorbed into the skin.
  20. 20Like other types of silica, this ingredient can be used to thicken a product. As an absorbent, it may be used to absorb extra water or help prevent clumping.
Source · skinsort.com
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Product index

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Comparison edit

Read side by side