Puca – Pure & Care Serum Argireline Versus Paula's Choice Pro-Collagen Multi-Peptide Booster

Puca – Pure & Care Serum Argireline Versus Paula's Choice Pro-Collagen Multi-Peptide Booster

This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Sodium Hyaluronate to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Glycerin

Corn Gluten Amino Acids

Glyceryl Glucoside

Saccharide Isomerate

Acetyl Hexapeptide-8

Sodium Hyaluronate

Aloe Barbadensis Leaf Extract

Yeast Ferment Extract

Panthenol

Avena Sativa Kernel Extract

Mentha Arvensis Leaf Extract

Pelargonium Graveolens Extract

Sophora Flavescens Root Extract

Chrysanthemum Indicum Flower Extract

Portulaca Oleracea Extract

Caprylyl Glycol

Hexylene Glycol

Butylene Glycol

Xanthan Gum

Citric Acid

Sodium Citrate

1,2-Hexanediol

Phenoxyethanol

Potassium Sorbate

Sodium Benzoate

Sodium Hydroxide

Ethylhexylglycerin

Hydroxyacetophenone

Water, Propanediol, Glycerin, Corn Gluten Amino Acids, Glyceryl Glucoside, Saccharide Isomerate, Acetyl Hexapeptide-8, Sodium Hyaluronate, Aloe Barbadensis Leaf Extract, Yeast Ferment Extract, Panthenol, Avena Sativa Kernel Extract, Mentha Arvensis Leaf Extract, Pelargonium Graveolens Extract, Sophora Flavescens Root Extract, Chrysanthemum Indicum Flower Extract, Portulaca Oleracea Extract, Caprylyl Glycol, Hexylene Glycol, Butylene Glycol, Xanthan Gum, Citric Acid, Sodium Citrate, 1,2-Hexanediol, Phenoxyethanol, Potassium Sorbate, Sodium Benzoate, Sodium Hydroxide, Ethylhexylglycerin, Hydroxyacetophenone

Pentylene Glycol

Hydrolyzed Yeast Extract

Pyrus Malus Fruit Extract

Dimethicone

Ceramide AP

Palmitoyl Tetrapeptide-72 Amide

Sh-Polypeptide-121

Tridecapeptide-1

Polyglucuronic Acid

C9-12 Alkane

Ammonium Polyacryloyldimethyl Taurate

Polygonum Bistorta Root Extract

Bacillus Ferment

Lecithin

Sodium Phytate

Coco-Caprylate/Caprate

Cetyl Hydroxyethylcellulose

Magnesium Chloride

Water, Glycerin, Pentylene Glycol, Hydrolyzed Yeast Extract, Pyrus Malus Fruit Extract, Dimethicone, Propanediol, Ceramide AP, 1,2-Hexanediol, Glyceryl Glucoside, Palmitoyl Tetrapeptide-72 Amide, Sh-Polypeptide-121, Tridecapeptide-1, Polyglucuronic Acid, Sodium Hyaluronate, C9-12 Alkane, Ammonium Polyacryloyldimethyl Taurate, Polygonum Bistorta Root Extract, Bacillus Ferment, Lecithin, Sodium Phytate, Coco-Caprylate/Caprate, Hexylene Glycol, Cetyl Hydroxyethylcellulose, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Magnesium Chloride, Potassium Sorbate, Sodium Benzoate

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Glucoside is made from glycerol and glucose.

It is a humectant. Humectants help hydrate your skin by drawing moisture to it from the air.

Some foods that contain glyceryl glucoside include sake, miso, and wines.

Hexylene Glycol is a multitasker ingredient that works as a solvent, humectant, emulsifier, viscosity reducer, and preservative booster.

It is able to dissolve both water and oil-soluble ingredients to stabilize tricky actives and make products spread more easily.

As a humectant, it pulls water into the skin. But it's a pretty minor moisturizing ingredient compared to other humectants, like glycerin.

Interestingly, it can act as a mild penetration enhancer. One in vitro study on human skin found a 12% concentration upped the absorption of mometasone furoate (a medicinal ingredient used to treat inflammatory skin conditions) up to 7%.

This ingredient is typically used at levels of 0.1-10% depending on the role it's playing.

A patch test study on eczema patients didn't find a significant increase in irritation versus the control group, but the potential for irritation rises at higher concentrations.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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