Skin science article
PURITO B5 Panthenol Re-Barrier Cream Versus Mizon Peptide Ampoule Cream
PURITO B5 Panthenol Re-Barrier Cream Versus Mizon Peptide Ampoule Cream This barrier-repair moisturizer is formulated around Centella Asiatica Extract and Panthenol to strengthen the skin barrier and calm redness. This anti-aging ampoule is formulated around C
PURITO B5 Panthenol Re-Barrier Cream Versus Mizon Peptide Ampoule Cream
This barrier-repair moisturizer is formulated around Centella Asiatica Extract and Panthenol to strengthen the skin barrier and calm redness.
This anti-aging ampoule is formulated around Copper Tripeptide-1 and Adenosine to soften the look of wrinkles and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Centella Asiatica Extract
Panthenol 10%
Squalane
Butylene Glycol
Water
1,2-Hexanediol
Niacinamide
Hydrolyzed Jojoba Esters
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Hydroxyacetophenone
Tromethamine
Dipotassium Glycyrrhizate
Ethylhexylglycerin
Disodium EDTA
Xanthan Gum
Sodium Hyaluronate
Madecassoside
Asiaticoside
Asiatic Acid
Copper Tripeptide-1
Madecassic Acid
Centella Asiatica Extract, Panthenol 10%, Squalane, Butylene Glycol, Water, 1,2-Hexanediol, Niacinamide, Hydrolyzed Jojoba Esters, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Hydroxyacetophenone, Tromethamine, Dipotassium Glycyrrhizate, Ethylhexylglycerin, Disodium EDTA, Xanthan Gum, Sodium Hyaluronate, Madecassoside, Asiaticoside, Asiatic Acid, Copper Tripeptide-1, Madecassic Acid
Stearic Acid
Neopentyl Glycol Diheptanoate
Cetearyl Olivate
Sorbitan Olivate
Hydrogenated Poly(C6-14 Olefin)
Glycerin
Cyclomethicone
Glyceryl Stearate
PEG-100 Stearate
Polyacrylate-13
Polyisobutene
Polysorbate 20
Cetearyl Alcohol
Cetearyl Glucoside
Dimethicone
Trehalose
Theobroma Cacao Extract
Caprylyl Glycol
Tropolone
Triethanolamine
Coptis Japonica Extract
Adenosine
Propylene Glycol
Hydrolyzed Extensin
Rubus Idaeus Fruit Extract
Beta-Glucan
Biosaccharide Gum-1
Iris Florentina Root Extract
Hydrolyzed Wheat Protein
Prunus Amygdalus Dulcis Seed Extract
Lavandula Angustifolia Oil
Water, Stearic Acid, Neopentyl Glycol Diheptanoate, Cetearyl Olivate, Sorbitan Olivate, Hydrogenated Poly(C6-14 Olefin), Glycerin, Cyclomethicone, Butylene Glycol, Copper Tripeptide-1, Glyceryl Stearate, PEG-100 Stearate, Polyacrylate-13, Polyisobutene, Polysorbate 20, Cetearyl Alcohol, Cetearyl Glucoside, Dimethicone, Trehalose, Theobroma Cacao Extract, Caprylyl Glycol, Ethylhexylglycerin, Tropolone, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Triethanolamine, Coptis Japonica Extract, Adenosine, Propylene Glycol, Hydrolyzed Extensin, Rubus Idaeus Fruit Extract, Beta-Glucan, Biosaccharide Gum-1, Iris Florentina Root Extract, Hydrolyzed Wheat Protein, Prunus Amygdalus Dulcis Seed Extract, Lavandula Angustifolia Oil, Disodium EDTA
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ammonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.
Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy.
The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's:
Due to its large molecular size, it sits on the surface of skin rather than penetrating it.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.
It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.
While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.
Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.
Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.
Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.
For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.
After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.
While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.
Read more about other common types of peptides here:
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!