Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Q + A Peptide Serum Versus U beauty Resurfacing Compound

Q + A Peptide Serum Versus U beauty Resurfacing Compound This anti-aging serum is formulated around Aloe Barbadensis Leaf Juice Powder and Tripeptide-29 to soften the look of wrinkles and hydrate skin. This smoothing serum is formulated around Sodium Ascorbyl

Q + A Peptide Serum Versus U beauty Resurfacing Compound

This anti-aging serum is formulated around Aloe Barbadensis Leaf Juice Powder and Tripeptide-29 to soften the look of wrinkles and hydrate skin.

This smoothing serum is formulated around Sodium Ascorbyl Phosphate and Glycolic Acid to refine skin texture and brighten dull-looking skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propylene Glycol

Betaine

Pentylene Glycol

Xanthan Gum

Aloe Barbadensis Leaf Juice Powder

Sodium Phytate

Glycerin

Lonicera Caprifolium Flower Extract

Biosaccharide Gum-1

Lonicera Japonica Flower Extract

Sodium Levulinate

Tripeptide-29

Sodium Hyaluronate

Sodium Ascorbyl Phosphate

Magnesium PCA

Lactic Acid

Glyceryl Caprylate

Cocoyl Proline

Sodium Anisate

Leuconostoc/Radish Root Ferment Filtrate

Citric Acid

Water, Propylene Glycol, Betaine, Pentylene Glycol, Xanthan Gum, Aloe Barbadensis Leaf Juice Powder, Sodium Phytate, Glycerin, Lonicera Caprifolium Flower Extract, Biosaccharide Gum-1, Lonicera Japonica Flower Extract, Sodium Levulinate, Tripeptide-29, Sodium Hyaluronate, Sodium Ascorbyl Phosphate, Magnesium PCA, Lactic Acid, Glyceryl Caprylate, Cocoyl Proline, Sodium Anisate, Leuconostoc/Radish Root Ferment Filtrate, Citric Acid

Dimethyl Sulfone

Polysorbate 20

Hamamelis Virginiana Leaf Extract

Glycolic Acid

Superoxide Dismutase

Lactobionic Acid

Hydrolyzed Hyaluronic Acid

Glutathione

Simmondsia Chinensis Seed Oil

Mandelic Acid

Linoleic Acid

Retinyl Palmitate

Helianthus Annuus Seed Oil

Oleic Acid

Palmitic Acid

Stearic Acid

Tocopherol

Linolenic Acid

Butylene Glycol

Methyldihydrojasmonate

Hydroxyphenyl Propamidobenzoic Acid

Caprylyl Glycol

N-Prolyl Palmitoyl Tripeptide-56 Acetate

Benzyl Alcohol

Dehydroacetic Acid

Water, Aloe Barbadensis Leaf Juice Powder, Sodium Ascorbyl Phosphate, Dimethyl Sulfone, Citric Acid, Polysorbate 20, Glycerin, Hamamelis Virginiana Leaf Extract, Sodium Hyaluronate, Glycolic Acid, Superoxide Dismutase, Lactobionic Acid, Hydrolyzed Hyaluronic Acid, Glutathione, Simmondsia Chinensis Seed Oil, Mandelic Acid, Linoleic Acid, Retinyl Palmitate, Helianthus Annuus Seed Oil, Oleic Acid, Palmitic Acid, Stearic Acid, Tocopherol, Linolenic Acid, Xanthan Gum, Pentylene Glycol, Butylene Glycol, Methyldihydrojasmonate, Hydroxyphenyl Propamidobenzoic Acid, Caprylyl Glycol, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Benzyl Alcohol, Dehydroacetic Acid

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Aloe Barbadensis Leaf Juice Powder comes from the aloe plant.

You may know Aloe to be a good sunburn reliever and inflammation reducer. This is because it contains many components that are known to help reduce irritation and itchiness.

Aloe leaves are also great moisturizers. They are naturally rich in polysaccharides, a carbohydrate made of sugars. Polysaccharides are able to mimic the carbs found in the top layer of your skin. This can help keep your skin hydrated.

Aloe contains the antioxidants Vitamins A, C, and E. These vitamins neutralize free radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

Aloe does not protect against UV rays, despite it soothing sunburns.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Sodium Ascorbyl Phosphate (SAP) is a water-soluble form of Vitamin C. It is the salt of ascorbic acid.

This ingredient is commonly used in skincare because it's more formulation-stable while still offering the same benefits as pure ascorbic acid. Ascorbic acid is notorious for breaking down when exposed to sunlight and oxygen whereas SAP has been shown to be more stable.

Studies show SAP has anti-acne and antioxidant benefits. One study found 5% of SAP lotion to be an effective ingredient for treating acne vulgaris. This is because research shows that SAP may help control acne by reducing acne-causing bacteria and slowing the oxidation of skin oils caused by UV exposure.

In addition to acne, vitamin C is important for skin structure. Lab studies suggest SAP may support collagen production in skin cells, making it a great ingredient in anti-aging routines.

Vitamin C has many benefits: it helps reduce redness, improve skin texture, fade the appearance of dark spots, and brighten the skin.

Read more about other types of Vitamin C:

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
  4. 04Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
  5. 05However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
  6. 06Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
  7. 07In skincare formulas, citric acid can:
  8. 08While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
  9. 09Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
  10. 10Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
  11. 11However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's…
  12. 12Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  13. 13Topically, glycerin does several things at once:
  14. 14Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  15. 15Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  16. 16This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  17. 17Just know very high concentrations (>40%) can feel tacky in low humidity.
  18. 18Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  19. 19Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
  20. 20In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Source · skinsort.com
02

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Comparison edit

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