QMS Medicosmetics Day Collagen Serum Versus Charlotte Tilbury Charlotte's Magic Serum Crystal Elixir

QMS Medicosmetics Day Collagen Serum Versus Charlotte Tilbury Charlotte's Magic Serum Crystal Elixir

This anti-aging serum is formulated around Aloe Barbadensis Leaf Juice and Atelocollagen to soften the look of wrinkles and hydrate skin.

This anti-aging serum is formulated around Niacinamide and Polyglutamic Acid to soften the look of wrinkles and brighten dull-looking skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Aloe Barbadensis Leaf Juice

Glycerin

Pentylene Glycol

Propylene Glycol

Polyglyceryl-4 Caprate

Atelocollagen

Sodium Hyaluronate

Tocopheryl Acetate

Panthenol

Bis(Tripeptide-1) Copper Acetate

Glycoproteins

Caprylyl Glycol

Phenoxyethanol

Citric Acid

Butylene Glycol

Dipropylene Glycol

Carrageenan

Glyceryl Caprylate

Tetrasodium Glutamate Diacetate

Sodium Phytate

Arginine

Sodium Lactate

Xanthan Gum

Carbomer

Coco-Glucoside

Hexyl Cinnamal

Glycine

Parfum

Proline

Sorbitol

Potassium Sorbate

Linalool

Benzyl Benzoate

Sodium Hydroxide

Sodium Benzoate

Dipotassium Phosphate

Alcohol

Palmitoyl Tripeptide-1

Hydrolyzed Soy Protein

Palmitoyl Tetrapeptide-7

Water, Aloe Barbadensis Leaf Juice, Glycerin, Pentylene Glycol, Propylene Glycol, Polyglyceryl-4 Caprate, Atelocollagen, Sodium Hyaluronate, Tocopheryl Acetate, Panthenol, Bis(Tripeptide-1) Copper Acetate, Glycoproteins, Caprylyl Glycol, Phenoxyethanol, Citric Acid, Butylene Glycol, Dipropylene Glycol, Carrageenan, Glyceryl Caprylate, Tetrasodium Glutamate Diacetate, Sodium Phytate, Arginine, Sodium Lactate, Xanthan Gum, Carbomer, Coco-Glucoside, Hexyl Cinnamal, Glycine, Parfum, Proline, Sorbitol, Potassium Sorbate, Linalool, Benzyl Benzoate, Sodium Hydroxide, Sodium Benzoate, Dipotassium Phosphate, Alcohol, Palmitoyl Tripeptide-1, Hydrolyzed Soy Protein, Palmitoyl Tetrapeptide-7

Niacinamide

Glycereth-26

Triheptanoin

Methyl Gluceth-20

Silica

Camellia Oleifera Seed Oil

Quartz Powder

Amethyst Powder

Ruby Powder

Gold

Butyrospermum Parkii Oil

Dimethyl Isosorbide

Polysorbate 20

Glyceryl Stearate

Octyldodecyl Oleate

Benzyl Alcohol

Myrothamnus Flabellifolia Leaf Extract

PEG-100 Stearate

Octyldodecyl Stearoyl Stearate

Schisandra Chinensis Fruit Extract

Sodium Gluconate

Chondrus Crispus Extract

Saussurea Involucrata Callus Extract

Polyglutamic Acid

Magnesium Aspartate

Zinc Gluconate

Rosa Canina Fruit Extract

Polyhydroxystearic Acid

Octyldodecanol

Propanediol

Biosaccharide Gum-4

Plumeria Alba Flower Extract

Plumeria Rubra Flower Extract

Lithothamnion Calcareum Extract

Lactic Acid

Copper Gluconate

Hydrated Silica

1,2-Hexanediol

Solanum Tuberosum Pulp Extract

Acetyl Tetrapeptide-11

Acetyl Tetrapeptide-9

Dehydroacetic Acid

Ascorbic Acid

Glutathione

Limonene

Geraniol

Citronellol

Citral

Water, Niacinamide, Glycereth-26, Triheptanoin, Glycerin, Methyl Gluceth-20, Silica, Camellia Oleifera Seed Oil, Quartz Powder, Amethyst Powder, Ruby Powder, Gold, Butyrospermum Parkii Oil, Phenoxyethanol, Dimethyl Isosorbide, Polysorbate 20, Glyceryl Stearate, Butylene Glycol, Octyldodecyl Oleate, Benzyl Alcohol, Myrothamnus Flabellifolia Leaf Extract, PEG-100 Stearate, Octyldodecyl Stearoyl Stearate, Schisandra Chinensis Fruit Extract, Carbomer, Sodium Gluconate, Sodium Hyaluronate, Chondrus Crispus Extract, Sodium Hydroxide, Saussurea Involucrata Callus Extract, Tocopheryl Acetate, Aloe Barbadensis Leaf Juice, Polyglutamic Acid, Pentylene Glycol, Sorbitol, Magnesium Aspartate, Zinc Gluconate, Rosa Canina Fruit Extract, Polyhydroxystearic Acid, Octyldodecanol, Sodium Benzoate, Propanediol, Biosaccharide Gum-4, Xanthan Gum, Parfum, Plumeria Alba Flower Extract, Plumeria Rubra Flower Extract, Lithothamnion Calcareum Extract, Lactic Acid, Potassium Sorbate, Caprylyl Glycol, Copper Gluconate, Hydrated Silica, 1,2-Hexanediol, Citric Acid, Solanum Tuberosum Pulp Extract, Acetyl Tetrapeptide-11, Acetyl Tetrapeptide-9, Dehydroacetic Acid, Ascorbic Acid, Glutathione, Limonene, Geraniol, Citronellol, Linalool, Citral

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Aloe Barbadensis Leaf Juice is the filtered, stabilized liquid pressed from the inner gel of the aloe vera leaf.

In cosmetics, it shows up as either soothing active or a water-replacement base. It is roughly 98-99% water and the last 1-2% is an interesting mix of polysaccharides, amino acids, vitamins, minerals, and enzymes.

The polysaccharides do most of the work: they bind water at the skin surface for a light, non-greasy hydration boost. And one of the polysaccharides, glycomannan, is linked to fibroblast stimulation + collagen synthesis. This is also why aloe has such a long track record in wound and burn healing.

This ingredient is also calming with anti-inflammatory and mild antimicrobial activity, making it a great pick for sensitive, irritated, or post-sun skin.

Realistic expectations matter though; the solid evidence is mostly limited to hydration, soothing, and wound support. Deeper claims about anti-aging or sun protection are not well backed, and science reviews note it does not prevent radiation-induced skin injury.

Because it plays well with almost everything, it's commonly used as a base alongside other actives like niacinamide or vitamin C.

Typical usage concentrations range from 0.5% (where hydration benefits already show up) all the way to 90%+ (where it replaces water as the main base).

The safety for this ingredient is well-establish as well. Overall, this is a great supporting ingredient for those who want a boost in hydration.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Linalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.

Like Limonene, this ingredient oxidizes when exposed to air. Oxidized linalool can cause allergies and skin sensitivity.

This ingredient has a scent that is floral, spicy tropical, and citrus-like.

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Sorbitol is a sugar alcohol. It is a hydrating and moisturizing agent created from the reduction process of glucose.

Most sorbitol is usually made from potato starch. It is also found in fruits such as apples and pears.

As a humectant, Sorbitol helps draw water to the skin. This helps keep the skin hydrated. Sorbitol also helps create a thicker texture in products. You might find sorbitol in your toothpaste and other gels.

It is a non-irritating ingredient that is great for those with dry skin.

Sorbitol is a prebiotic. It helps promote the growth of healthy bacteria on your skin. The bacteria on your skin form a microbiome. This microbiome helps protect your skin from infection and harmful bacteria.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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