Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Sephora Collection Hydrating Serum Versus Neutrogena Hydro Boost Hyaluronic Acid Serum

Sephora Collection Hydrating Serum Versus Neutrogena Hydro Boost Hyaluronic Acid Serum This hydrating serum is formulated around Hydrolyzed Sodium Hyaluronate and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier. This hydrating serum is formu

Sephora Collection Hydrating Serum Versus Neutrogena Hydro Boost Hyaluronic Acid Serum

This hydrating serum is formulated around Hydrolyzed Sodium Hyaluronate and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.

This hydrating serum is formulated around Panthenol and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Triethyl Citrate

Diglycerin

Pentylene Glycol

Methylpropanediol

Glycerin

Hydrolyzed Sodium Hyaluronate

Sodium Hyaluronate

Maltodextrin

Xanthan Gum

Sodium Benzoate

Sodium Phytate

Citric Acid

Polyglutamic Acid

Sclerotium Gum

Erythritol

Water, Triethyl Citrate, Diglycerin, Pentylene Glycol, Methylpropanediol, Glycerin, Hydrolyzed Sodium Hyaluronate, Sodium Hyaluronate, Maltodextrin, Xanthan Gum, Sodium Benzoate, Sodium Phytate, Citric Acid, Polyglutamic Acid, Sclerotium Gum, Erythritol

Butylene Glycol

Panthenol

Phenoxyethanol

Chlorphenesin

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Trehalose

Xylitylglucoside

Anhydroxylitol

Disodium EDTA

Sodium Hydroxide

Yeast Extract

Xylitol

Hydrolyzed Hyaluronic Acid

Carrageenan

Agar

Potassium Chloride

Ultramarines

Titanium Dioxide

Water, Glycerin, Butylene Glycol, Panthenol, Pentylene Glycol, Phenoxyethanol, Chlorphenesin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Trehalose, Xylitylglucoside, Sodium Hyaluronate, Anhydroxylitol, Disodium EDTA, Sodium Hydroxide, Yeast Extract, Xylitol, Hydrolyzed Hyaluronic Acid, Carrageenan, Agar, Potassium Chloride, Xanthan Gum, Ultramarines, Titanium Dioxide

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 031,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
  4. 04It is a:
  5. 05Humectant, drawing moisture into the skin
  6. 06Emollient, helping to soften skin
  7. 07Solvent, dispersing and stabilizing formulas
  8. 08Preservative booster, enhancing the antimicrobial activity of other preservatives
  9. 09Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  10. 10Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  11. 11Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  12. 12Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
  13. 13Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
  14. 14It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
  15. 15Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
  16. 16A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
  17. 17Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  18. 18Topically, glycerin does several things at once:
  19. 19Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  20. 20Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
Source · skinsort.com
02

Product index

Related product references

Product

Kylie Skin Hyaluronic Acid Serum

Kylie Skin Hyaluronic Acid Serum Ingredients in Kylie Skin Hyaluronic Acid Serum explained: benefits, concerns, and detailed analysis of 35 ingredients including Water, Glycerin, and Propan…

Source: skinsort.comView reference →

Product

Le Mieux Hyaluronic Acid Serum

Le Mieux Hyaluronic Acid Serum Le Mieux Hyaluronic Acid Serum ingredients explained: Hyaluronic Acid, Panthenol (Vitamin B5), Ginkgo Biloba Extract, Camellia Sinensis (Green Tea) Leaf Extra…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side

04

Ask the journal

Related questions

01When and How to Use Hyaluronic Acid in Your Routine

Products with hyaluronic acid can be used in the morning or at night (or both!). Applying the hydrating ingredient at night will restore your skin’s resilience while you sleep, and applying it in the morning will leave your skin feeling plump, hydrated and ready for makeup. Hyaluronic acid is great at providing topical hydration when it’s introduced into a balanced skincare routine. According to Dr. King, it’s important to pair your hyaluronic acid products with an emollient or occlusive moisturizer to lock in hydration.

Source · www.skincare.com
02How to Apply Face Serums

Skincare rules can get confusing, but when it comes to application the general rule of thumb is to pay attention to the product’s consistency. “Apply the lightest, thinnest product first and the heaviest, and more dense products last, since thinner products can’t penetrate thicker products,”says Dr. Lewis. After cleansing the face and following up with a toner, let the skin dry before using a serum. You can layer different serums on top of each other or opt for a product that has a precise mix of multiple hero ingredients, such as hyaluronic acid and vitamin C.

Source · www.skincare.com