Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Skin Deva 20% Argireline + Matrixyl 3000 + Hyaluronic Acid Serum Versus Skin Deva Coenzyme Q10 + Matrixyl 3000 + Hyaluronic Acid Serum

Skin Deva 20% Argireline + Matrixyl 3000 + Hyaluronic Acid Serum Versus Skin Deva Coenzyme Q10 + Matrixyl 3000 + Hyaluronic Acid Serum This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Matrixyl 3000 to soften the look of wrinkles and hydrate

Skin Deva 20% Argireline + Matrixyl 3000 + Hyaluronic Acid Serum Versus Skin Deva Coenzyme Q10 + Matrixyl 3000 + Hyaluronic Acid Serum

This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Matrixyl 3000 to soften the look of wrinkles and hydrate skin.

This anti-aging serum is formulated around Ubiquinone and Matrixyl 3000 to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Acetyl Hexapeptide-8 20%

Matrixyl 3000

Aloe Barbadensis Leaf Extract

Glycerin

Hyaluronic Acid

Benzyl Alcohol

Dehydroacetic Acid

Water, Acetyl Hexapeptide-8 20%, Matrixyl 3000, Aloe Barbadensis Leaf Extract, Glycerin, Hyaluronic Acid, Benzyl Alcohol, Dehydroacetic Acid

Ubiquinone

Aloe Barbadensis Sprout

Tocopherol

Water, Ubiquinone, Aloe Barbadensis Sprout, Matrixyl 3000, Glycerin, Hyaluronic Acid, Tocopherol, Benzyl Alcohol, Dehydroacetic Acid

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Benzyl Alcohol is an aromatic alcohol with several roles: it's a preservative, solvent, and mild fragrance component with a floral scent.

This ingredient has been deemed safe for use in cosmetic formulations at concentrations up to 5%, and up to 10% in hair dyes. You'll typically see 0.5-2% in most rinse-off or leave-on products.

As a preservative, it works by disrupting the membrane of microbial proteins. This helps keep bacteria and fungi from growing in your products.

The sensitization picture is actually quite assuring as well:of nearly 71,000 patients patch tested with benzyl alcohol, only 0.21% showed a positive reaction with most of them being weakly positive.

This led researchers to conclude that benzyl alcohol cannot be regarded as a significant contact allergen.

It is worth noting this ingredient is classified as one of the EU's regulated fragrance allergens and restricted to 1% in finished products.

Labels must also declare it in concentrations above 0.001% in leave-on products and 0.01% in rinse-off products.

At concentrations around 5%, localized redness and itching can appear as a direct irritant response and not as a true allergic reaction.

Dehydroacetic Acid is a synthetic preservative that keeps your products safe from microbes.

As an organic acid, it penetrates microbial cell walls and disrupts cellular metabolism. This makes it effective against bacteria, yeast, and mold.

It is effective at low concentrations (<0.6%). Clinical studies have found it to be non-irritating, non-sensitizing, and non-photosensitizing.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.

Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.

The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

This is why the best HA serums blend the two sizes together so you get the best of both worlds.

The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.

A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.

These are some other common types of Hyaluronic Acid:

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

This famous peptide is a blend of various INCI ingredients.

Read more about the benefits of the peptides in this mix, Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7.

Or learn more about the other ingredients: Glycerin, Water, Butylene Glycol, Carbomer, Polysorbate 20.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Glycerin
  3. 03Propanediol
  4. 04Diglycerin
  5. 05Niacinamide
  6. 06Squalane
  7. 07Polyacrylate Crosspolymer-6
  8. 08Allantoin
  9. 09Phenoxyethanol
  10. 10Bisabolol
  11. 11Sodium Polyacrylate
  12. 12Polyglutamic Acid
  13. 13Malachite Extract
  14. 14Tocopherol
  15. 15Disodium EDTA
  16. 16Methylparaben
  17. 17Ethylparaben
  18. 18Opuntia Ficus-Indica Stem Extract
  19. 19Propylene Glycol
  20. 20Zingiber Officinale Root Extract
Source · skinsort.com
02

Product index

Related product references

Product

Eva Naturals Hyaluronic Acid Serum

Eva Naturals Hyaluronic Acid Serum Eva Naturals Hyaluronic Acid Serum ingredients explained: Aqua (Distilled Water), Carbomer, Xanthan Gum, Hyaluronic Acid, Lavandula Angustifolia (Lavender…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side

04

Ask the journal

Related questions

01How to Apply Face Serums

Skincare rules can get confusing, but when it comes to application the general rule of thumb is to pay attention to the product’s consistency. “Apply the lightest, thinnest product first and the heaviest, and more dense products last, since thinner products can’t penetrate thicker products,”says Dr. Lewis. After cleansing the face and following up with a toner, let the skin dry before using a serum. You can layer different serums on top of each other or opt for a product that has a precise mix of multiple hero ingredients, such as hyaluronic acid and vitamin C.

Source · www.skincare.com
02When and How to Use Hyaluronic Acid in Your Routine

Products with hyaluronic acid can be used in the morning or at night (or both!). Applying the hydrating ingredient at night will restore your skin’s resilience while you sleep, and applying it in the morning will leave your skin feeling plump, hydrated and ready for makeup. Hyaluronic acid is great at providing topical hydration when it’s introduced into a balanced skincare routine. According to Dr. King, it’s important to pair your hyaluronic acid products with an emollient or occlusive moisturizer to lock in hydration.

Source · www.skincare.com