Skin science article
SKIN1004 Hyalu-Cica First Ampoule Versus JUMISO Waterfull Hyaluronic Acid Serum
SKIN1004 Hyalu-Cica First Ampoule Versus JUMISO Waterfull Hyaluronic Acid Serum This hydrating ampoule is formulated around Centella Asiatica Extract and Niacinamide to hydrate skin and calm redness. This hydrating serum is formulated around Sodium Hyaluronate
SKIN1004 Hyalu-Cica First Ampoule Versus JUMISO Waterfull Hyaluronic Acid Serum
This hydrating ampoule is formulated around Centella Asiatica Extract and Niacinamide to hydrate skin and calm redness.
This hydrating serum is formulated around Sodium Hyaluronate and Hydrolyzed Hyaluronic Acid to hydrate skin and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Centella Asiatica Extract 92%
Butylene Glycol
Niacinamide
1,2-Hexanediol
Water
Hydroxyacetophenone
Carbomer
Glycereth-25 PCA Isostearate
Ethylhexylglycerin
Tromethamine
Sodium Hyaluronate
Betula Platyphylla Japonica Juice
Melia Azadirachta Leaf Extract
Melia Azadirachta Flower Extract
Propanediol
Musa Sapientum Flower Extract
Coccinia Indica Fruit Extract
Rosa Damascena Flower Water
Pyrus Communis Fruit Extract
Prunus Domestica Fruit Extract
Aloe Barbadensis Flower Extract
Cucumis Melo Fruit Extract
Solanum Melongena Fruit Extract
Hedera Helix Leaf/Stem Extract
Ocimum Sanctum Leaf Extract
Glycerin
Anastatica Hierochuntica Extract
Corallina Officinalis Extract
Curcuma Longa Root Extract
Hyaluronic Acid
Hydrolyzed Hyaluronic Acid
Portulaca Oleracea Extract
Artemisia Princeps Leaf Extract
Rhodiola Rosea Root Extract
Centella Asiatica Extract 92%, Butylene Glycol, Niacinamide, 1,2-Hexanediol, Water, Hydroxyacetophenone, Carbomer, Glycereth-25 PCA Isostearate, Ethylhexylglycerin, Tromethamine, Sodium Hyaluronate, Betula Platyphylla Japonica Juice, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Propanediol, Musa Sapientum Flower Extract, Coccinia Indica Fruit Extract, Rosa Damascena Flower Water, Pyrus Communis Fruit Extract, Prunus Domestica Fruit Extract, Aloe Barbadensis Flower Extract, Cucumis Melo Fruit Extract, Solanum Melongena Fruit Extract, Hedera Helix Leaf/Stem Extract, Ocimum Sanctum Leaf Extract, Glycerin, Anastatica Hierochuntica Extract, Corallina Officinalis Extract, Curcuma Longa Root Extract, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Portulaca Oleracea Extract, Artemisia Princeps Leaf Extract, Rhodiola Rosea Root Extract
Dipropylene Glycol
Pentylene Glycol
Chlorella Vulgaris Extract
Betaine
Panthenol
Trehalose
Polyglyceryl-10 Laurate
Glucose
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Fructooligosaccharides
Fructose
Glyceryl Acrylate/Acrylic Acid Copolymer
Allantoin
Choleth-24
Hydrogenated Lecithin
Tocopherol
Ceramide NP
Xanthan Gum
Water, Butylene Glycol, Glycerin, Dipropylene Glycol, 1,2-Hexanediol, Pentylene Glycol, Sodium Hyaluronate, Chlorella Vulgaris Extract, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Betaine, Panthenol, Trehalose, Polyglyceryl-10 Laurate, Glucose, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Fructooligosaccharides, Fructose, Tromethamine, Ethylhexylglycerin, Glyceryl Acrylate/Acrylic Acid Copolymer, Allantoin, Choleth-24, Hydrogenated Lecithin, Tocopherol, Ceramide NP, Carbomer, Xanthan Gum
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.
Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.
The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
This is why the best HA serums blend the two sizes together so you get the best of both worlds.
The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.
A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.
These are some other common types of Hyaluronic Acid:
Hydrolyzed Hyaluronic Acid is hyaluronic acid (HA) that is broken down into lower molecular weight fragments.
It's a humectant that pulls and holds water in the skin to help with hydration, plumpness, and reduce transepidermal water loss.
Because hydrolyzed hyaluronic acid is smaller in size, it can slip past your outermost layer of skin more easily than full-sized HA.
Most formulations will combine all sizes to get the best of both worlds.
Typical usage levels range from 0.01-1%. Any percentage higher than 2% might become goopy and tacky.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Tromethamine (aka THAM) is a synthetic amino acid that shows up in skincare as a helper ingredient.
It functions as a pH adjuster to help neutralize acidic ingredients and set a formula's pH to the right spot.
This matters a lot because a lot of actives (like vitamin C) needs a specific pH to work well and feel comfortable on skin.
Concentration use ranges from 0.1-1.0% depending on the formula.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!