Skin science article
SKIN1004 Madagascar Centella Hyalu-Cica Sleeping Pack Versus Mary & May Calendula Peptide Ageless Sleeping Mask
SKIN1004 Madagascar Centella Hyalu-Cica Sleeping Pack Versus Mary & May Calendula Peptide Ageless Sleeping Mask This hydrating overnight mask is formulated around Centella Asiatica Leaf Water and Niacinamide to hydrate skin and calm redness. This anti-aging ov
SKIN1004 Madagascar Centella Hyalu-Cica Sleeping Pack Versus Mary & May Calendula Peptide Ageless Sleeping Mask
This hydrating overnight mask is formulated around Centella Asiatica Leaf Water and Niacinamide to hydrate skin and calm redness.
This anti-aging overnight mask is formulated around Acetyl Hexapeptide-8 and Copper Tripeptide-1 to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Centella Asiatica Leaf Water
Water
Butylene Glycol
Glycerin
1,2-Hexanediol
Niacinamide
Polyglutamic Acid
Pantolactone
Hydrolyzed Hibiscus Esculentus Extract
Carbomer
Panthenol
Sodium Hyaluronate
Hydrolyzed Hyaluronic Acid
Hyaluronic Acid
Cetearyl Olivate
Methylpropanediol
Arginine
Pullulan
Sorbitan Olivate
Caprylic/Capric Triglyceride
Pyrus Communis Fruit Extract
Adenosine
Rosa Damascena Flower Water
Cucumis Melo Fruit Extract
Iris Florentina Root Extract
Ethylhexylglycerin
Hedera Helix Leaf/Stem Extract
Sodium Phytate
Xanthan Gum
Maltodextrin
Artemisia Princeps Leaf Extract
Hydrolyzed Gardenia Florida Extract
Melatonin
Illicium Verum Fruit Extract
Larix Sibirica Wood Extract
Quercus Mongolica Leaf Extract
Persicaria Hydropiper Extract
Rheum Palmatum Root/Stalk Extract
Asarum Sieboldii Root Extract
Chrysanthellum Indicum Extract
Corydalis Turtschaninovii Root Extract
Coptis Chinensis Root Extract
Machilus Thunbergii Bark Extract
Pentylene Glycol
Hydrogenated Lecithin
Ceramide NP
Centella Asiatica Leaf Water, Water, Butylene Glycol, Glycerin, 1,2-Hexanediol, Niacinamide, Polyglutamic Acid, Pantolactone, Hydrolyzed Hibiscus Esculentus Extract, Carbomer, Panthenol, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Cetearyl Olivate, Methylpropanediol, Arginine, Pullulan, Sorbitan Olivate, Caprylic/Capric Triglyceride, Pyrus Communis Fruit Extract, Adenosine, Rosa Damascena Flower Water, Cucumis Melo Fruit Extract, Iris Florentina Root Extract, Ethylhexylglycerin, Hedera Helix Leaf/Stem Extract, Sodium Phytate, Xanthan Gum, Maltodextrin, Artemisia Princeps Leaf Extract, Hydrolyzed Gardenia Florida Extract, Melatonin, Illicium Verum Fruit Extract, Larix Sibirica Wood Extract, Quercus Mongolica Leaf Extract, Persicaria Hydropiper Extract, Rheum Palmatum Root/Stalk Extract, Asarum Sieboldii Root Extract, Chrysanthellum Indicum Extract, Corydalis Turtschaninovii Root Extract, Coptis Chinensis Root Extract, Machilus Thunbergii Bark Extract, Pentylene Glycol, Hydrogenated Lecithin, Ceramide NP
Alcohol Denat.
Betaine
Dipropylene Glycol
Gardenia Taitensis Callus Extract
Oak Root Extract
Tremella Fuciformis Extract
Centella Asiatica Extract
Ficus Carica Fruit Extract
Orchid Leaf/Root/Stem Extract
Chamomilla Recutita Extract
Chrysanthemum Parthenium Extract
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Tromethamine
Polyglyceryl-10 Laurate
Dextrin
Tocopherol
Acetyl Hexapeptide-8
Acetyl Octapeptide-3
Acetyl Tetrapeptide-2
Oligopeptide-6
Tripeptide-1
Copper Tripeptide-1
Hexapeptide-2
Dipeptide-2
Acetyl Tetrapeptide-3
Acetyl Tripeptide-1
Hexapeptide-9
Tripeptide-2
Nonapeptide-1
Pentapeptide-3
Tripeptide-3
Alanine/Histidine/Lysine Polypeptide Copper Hcl
Dipeptide-4
Acetyl Tetrapeptide-5
Palmitoyl Dipeptide-7
Palmitoyl Hexapeptide-12
Palmitoyl Tripeptide-1
Palmitoyl Tripeptide-5
Palmitoyl Pentapeptide-4
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Palmitoyl Tetrapeptide-7
Guaiazulene
Parfum
Water, Alcohol Denat., Methylpropanediol, 1,2-Hexanediol, Betaine, Dipropylene Glycol, Gardenia Taitensis Callus Extract, Oak Root Extract, Tremella Fuciformis Extract, Centella Asiatica Extract, Ficus Carica Fruit Extract, Orchid Leaf/Root/Stem Extract, Chamomilla Recutita Extract, Chrysanthemum Parthenium Extract, Hydrogenated Lecithin, Sodium Hyaluronate, Panthenol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glycerin, Tromethamine, Butylene Glycol, Polyglyceryl-10 Laurate, Dextrin, Sodium Phytate, Ceramide NP, Tocopherol, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Oligopeptide-6, Tripeptide-1, Copper Tripeptide-1, Hexapeptide-2, Dipeptide-2, Acetyl Tetrapeptide-3, Acetyl Tripeptide-1, Hexapeptide-9, Tripeptide-2, Nonapeptide-1, Pentapeptide-3, Tripeptide-3, Alanine/Histidine/Lysine Polypeptide Copper Hcl, Dipeptide-4, Acetyl Tetrapeptide-5, Palmitoyl Dipeptide-7, Palmitoyl Hexapeptide-12, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Pentapeptide-4, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tetrapeptide-7, Guaiazulene, Parfum, Ethylhexylglycerin
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Methylpropanediol is a synthetic solvent and humectant.
As a solvent, it helps dissolve other ingredients, helping to evenly distribute ingredients throughout the product. This ingredient has also been shown to have antimicrobial properties which makes it a preservative booster.
Methylpropanediol is able to add a bit of moisture to the skin. It also helps other ingredients be better absorbed into the skin, such as salicylic acid.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Sodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.
Sodium Phytate is a chelating agent. Chelating agents help prevent metals from binding to water. This helps stabilize the ingredients and the product.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!