Skin science article
SkinCeuticals A.G.E. Interrupter Advanced Versus SkinMedica TNS® Advanced+ Serum
SkinCeuticals A.G.E. Interrupter Advanced Versus SkinMedica TNS® Advanced+ Serum This anti-aging treatment is formulated around Niacinamide and Adenosine to soften the look of wrinkles and strengthen the skin barrier. What's inside Key Ingredients Benefits Con
SkinCeuticals A.G.E. Interrupter Advanced Versus SkinMedica TNS® Advanced+ Serum
This anti-aging treatment is formulated around Niacinamide and Adenosine to soften the look of wrinkles and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Hydroxypropyl Tetrahydropyrantriol
Glycerin
Propylene Glycol
Stearic Acid
Butyrospermum Parkii Butter
Hydroxyethylpiperazine Ethane Sulfonic Acid
Palmitic Acid
Pentylene Glycol
Oleyl Alcohol
Arachidyl Alcohol
Myristyl Myristate
Panthenol
Niacinamide
Dimethicone
Isononyl Isononanoate
Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone
Glyceryl Stearate
Candelilla Cera
Euphorbia Cerifera Cera
Behenyl Alcohol
PEG-100 Stearate
Sodium Polyacrylate
Pentaerythrityl Tetraisostearate
4-T-Butylcyclohexanol
Arachidyl Glucoside
Caprylyl Glycol
Xanthan Gum
Chlorphenesin
Myristic Acid
Caprylic/Capric Triglyceride
Glycyrrhetinic Acid
Parfum
Sorbitol
Vaccinium Myrtillus Fruit Extract
Potassium Hydroxide
Adenosine
Citric Acid
Punica Granatum Fruit Extract
Limonene
Coumarin
Linalool
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Water, Hydroxypropyl Tetrahydropyrantriol, Glycerin, Propylene Glycol, Stearic Acid, Butyrospermum Parkii Butter, Hydroxyethylpiperazine Ethane Sulfonic Acid, Palmitic Acid, Pentylene Glycol, Oleyl Alcohol, Arachidyl Alcohol, Myristyl Myristate, Panthenol, Niacinamide, Dimethicone, Isononyl Isononanoate, Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone, Glyceryl Stearate, Candelilla Cera, Euphorbia Cerifera Cera, Behenyl Alcohol, PEG-100 Stearate, Sodium Polyacrylate, Pentaerythrityl Tetraisostearate, 4-T-Butylcyclohexanol, Arachidyl Glucoside, Caprylyl Glycol, Xanthan Gum, Chlorphenesin, Myristic Acid, Caprylic/Capric Triglyceride, Glycyrrhetinic Acid, Parfum, Sorbitol, Vaccinium Myrtillus Fruit Extract, Potassium Hydroxide, Adenosine, Citric Acid, Punica Granatum Fruit Extract, Limonene, Coumarin, Linalool, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Human Neonatal Fibroblast Conditioned Media
Glycereth-7 Triacetate
Shea Butter Ethyl Esters
Ethoxydiglycol
Lactococcus Ferment Lysate
Whey Protein
Chlorella Vulgaris Extract
Saccharide Isomerate
Dimer Tripeptide-43
Vitis Vinifera Flower Cell Extract
Pyrus Malus Fruit Extract
Hydroxyacetophenone
Tocopheryl Acetate
Propanediol
Polyacrylate Crosspolymer-6
Polyacrylate-13
Polyisobutene
Sclerotium Gum
PEG-12 Dimethicone
Lecithin
Pullulan
Butylene Glycol
Sodium Citrate
Polysorbate 20
Aminomethyl Propanol
Disodium EDTA
Phenoxyethanol
Ethylhexylglycerin
Water, Pentylene Glycol, Human Neonatal Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Dimer Tripeptide-43, Vitis Vinifera Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.