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Skin science article

SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum Versus Vichy LiftActiv Supreme H.A. Wrinkle Corrector H.A. Serum

SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum Versus Vichy LiftActiv Supreme H.A. Wrinkle Corrector H.A. Serum This anti-aging serum is formulated around Dipeptide Diaminobutyroyl Benzylamide Diacetate and Acetyl Hexapeptide-8 to soften the look of wri

SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum Versus Vichy LiftActiv Supreme H.A. Wrinkle Corrector H.A. Serum

This anti-aging serum is formulated around Dipeptide Diaminobutyroyl Benzylamide Diacetate and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture.

This anti-aging serum is formulated around Sodium Hyaluronate and Dipeptide Diaminobutyroyl Benzylamide Diacetate to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Niacinamide

Gluconolactone

Butylene Glycol

PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin

Alcohol Denat.

Pentylene Glycol

Methyl Gluceth-20

Glycerin

Potassium Hydroxide

Hydroxyethylcellulose

Salicylic Acid

Chlorphenesin

Phytic Acid

Adenosine

Sodium Benzoate

Laminaria Digitata Extract

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Acetyl Hexapeptide-8

Water, Niacinamide, Gluconolactone, Butylene Glycol, PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin, Alcohol Denat., Pentylene Glycol, Methyl Gluceth-20, Glycerin, Potassium Hydroxide, Hydroxyethylcellulose, Salicylic Acid, Chlorphenesin, Phytic Acid, Adenosine, Sodium Benzoate, Laminaria Digitata Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetyl Hexapeptide-8

Hydroxyethylpiperazine Ethane Sulfonic Acid

Sodium Hyaluronate

PEG-60 Hydrogenated Castor Oil

Secale Cereale Seed Extract

Calcium Pantothenate

Phenoxyethanol

Ascorbyl Glucoside

Disodium EDTA

Water, Glycerin, Hydroxyethylpiperazine Ethane Sulfonic Acid, Sodium Hyaluronate, PEG-60 Hydrogenated Castor Oil, Secale Cereale Seed Extract, Calcium Pantothenate, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Phenoxyethanol, Chlorphenesin, Ascorbyl Glucoside, Disodium EDTA, Pentylene Glycol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.

Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.

Chlorphenesin is soluble in both water and glycerin.

Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.

This small molecule peptide has similar benefits to Argireline, the "botox" peptide.

According to the manufacturer, this peptide mimics snake venom to freeze muscles. This prevents muscle movement and contractions to prohibit the formation of fine lines and wrinkles.

While this seems promising, research is lacking in proving this ingredient to be as effective as botox.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Niacinamide
  3. 03Gluconolactone
  4. 04Butylene Glycol
  5. 05PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin
  6. 06Alcohol Denat.
  7. 07Pentylene Glycol
  8. 08Methyl Gluceth-20
  9. 09Glycerin
  10. 10Potassium Hydroxide
  11. 11Hydroxyethylcellulose
  12. 12Salicylic Acid
  13. 13Chlorphenesin
  14. 14Phytic Acid
  15. 15Adenosine
  16. 16Sodium Benzoate
  17. 17Laminaria Digitata Extract
  18. 18Dipeptide Diaminobutyroyl Benzylamide Diacetate
  19. 19Acetyl Hexapeptide-8
  20. 20Water, Niacinamide, Gluconolactone, Butylene Glycol, PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin, Alcohol Denat., Pentylene Glycol, Methyl Gluceth-20, Glycerin, Potassium Hydroxide, Hydroxyethylcellulose, Salicylic Acid, Chlorphenesin, Phytic Acid, A…
Source · skinsort.com
02

Product index

Related product references

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Aaron Carre Re:Turn Peptide Serum

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03

Comparison edit

Read side by side