SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator Versus SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum

SkinMedica HA5 Hydra Collagen Replenish + Restore Hydrator Versus SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum

This hydrating serum is formulated around Linoleic Acid and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.

This anti-aging serum is formulated around Dipeptide Diaminobutyroyl Benzylamide Diacetate and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Caprylic/Capric Triglyceride

Shorea Stenoptera Seed Butter

C9-12 Alkane

Propanediol

Linoleic Acid

Sodium Acrylates Copolymer

Passiflora Edulis Seed Oil

Sodium Hyaluronate

Hydrolyzed Hyaluronic Acid

Sodium Hyaluronate Crosspolymer

Nelumbo Nucifera Germ Extract

Collagen

Butyl Avocadate

Trehalose

Serine

Vitis Vinifera Flower Cell Extract

Linolenic Acid

Urea

Caprylhydroxamic Acid

Algin

Polyglutamic Acid

Tocopherol

Oleic Acid

Pullulan

Palmitic Acid

Glyceryl Glucoside

Coco-Caprylate/Caprate

Lecithin

1,2-Hexanediol

Pentylene Glycol

Stearic Acid

Benzoic Acid

Caprylyl Glycol

Polysorbate 20

Dehydroacetic Acid

Glyceryl Polyacrylate

Potassium Phosphate

Benzyl Alcohol

Disodium Phosphate

Sodium Benzoate

Water, Glycerin, Caprylic/Capric Triglyceride, Shorea Stenoptera Seed Butter, C9-12 Alkane, Propanediol, Linoleic Acid, Sodium Acrylates Copolymer, Passiflora Edulis Seed Oil, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Nelumbo Nucifera Germ Extract, Collagen, Butyl Avocadate, Trehalose, Serine, Vitis Vinifera Flower Cell Extract, Linolenic Acid, Urea, Caprylhydroxamic Acid, Algin, Polyglutamic Acid, Tocopherol, Oleic Acid, Pullulan, Palmitic Acid, Glyceryl Glucoside, Coco-Caprylate/Caprate, Lecithin, 1,2-Hexanediol, Pentylene Glycol, Stearic Acid, Benzoic Acid, Caprylyl Glycol, Polysorbate 20, Dehydroacetic Acid, Glyceryl Polyacrylate, Potassium Phosphate, Benzyl Alcohol, Disodium Phosphate, Sodium Benzoate

Niacinamide

Gluconolactone

Butylene Glycol

PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin

Alcohol Denat.

Methyl Gluceth-20

Potassium Hydroxide

Hydroxyethylcellulose

Salicylic Acid

Chlorphenesin

Phytic Acid

Adenosine

Laminaria Digitata Extract

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Acetyl Hexapeptide-8

Water, Niacinamide, Gluconolactone, Butylene Glycol, PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin, Alcohol Denat., Pentylene Glycol, Methyl Gluceth-20, Glycerin, Potassium Hydroxide, Hydroxyethylcellulose, Salicylic Acid, Chlorphenesin, Phytic Acid, Adenosine, Sodium Benzoate, Laminaria Digitata Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetyl Hexapeptide-8

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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