Skin science article
The INKEY List Bio-Active Ceramide Repairing and Plumping Moisturizer Versus Tocobo Multi Ceramide Cream
The INKEY List Bio-Active Ceramide Repairing and Plumping Moisturizer Versus Tocobo Multi Ceramide Cream This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Ceramide NP to strengthen the skin barrier and hydrate skin. This barr
The INKEY List Bio-Active Ceramide Repairing and Plumping Moisturizer Versus Tocobo Multi Ceramide Cream
This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Ceramide NP to strengthen the skin barrier and hydrate skin.
This barrier-repair moisturizer is formulated around Squalane and Panthenol to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Butyrospermum Parkii Butter
C12-15 Alkyl Benzoate
Propanediol
Polysilicone-11
C10-18 Triglycerides
Caprylic/Capric Triglyceride
Pentaerythrityl Tetraisostearate
Cetearyl Olivate
Sorbitan Olivate
Cetyl Alcohol
Phenoxyethanol
Ceramide NP
Polyacrylate-13
Hydrogenated Polyisobutene
Ethylhexylglycerin
Polyglyceryl-10 Laurate
Ethylhexyl Palmitate
Laureth-12
Sorbitan Isostearate
Hdi/Trimethylol Hexyllactone Crosspolymer
Polymethylsilsesquioxane
Citric Acid
Sodium Hydroxide
Water, Glycerin, Butyrospermum Parkii Butter, C12-15 Alkyl Benzoate, Propanediol, Polysilicone-11, C10-18 Triglycerides, Caprylic/Capric Triglyceride, Pentaerythrityl Tetraisostearate, Cetearyl Olivate, Sorbitan Olivate, Cetyl Alcohol, Phenoxyethanol, Ceramide NP, Polyacrylate-13, Hydrogenated Polyisobutene, Ethylhexylglycerin, Polyglyceryl-10 Laurate, Ethylhexyl Palmitate, Laureth-12, Sorbitan Isostearate, Hdi/Trimethylol Hexyllactone Crosspolymer, Polymethylsilsesquioxane, Citric Acid, Sodium Hydroxide
Squalane
Coco-Caprylate/Caprate
Polyglyceryl-3 Methylglucose Distearate
Pentylene Glycol
Polyglyceryl-3 Distearate
Cyclohexasiloxane
1,2-Hexanediol
Butylene Glycol
Diphenyl Dimethicone
Diphenylsiloxy Phenyl Trimethicone
Hydrogenated Coco-Glycerides
Cetearyl Alcohol
Glyceryl Stearate
Glucose
Chlorella Vulgaris Extract
Hydroxyacetophenone
Sodium Polyacrylate Starch
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Fructose
Fructooligosaccharides
Tromethamine
Parfum
Glyceryl Stearate Citrate
Panthenol
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Hydrogenated Lecithin
Sodium Phytate
Xanthan Gum
Stearic Acid
Hyaluronic Acid
Beta-Glucan
Hydrolyzed Hyaluronic Acid
Ceramide Ns
Cholesterol
Phytosphingosine
Sodium Hyaluronate
Ceramide AP
Ceramide As
Ceramide EOP
Water, Glycerin, Squalane, Coco-Caprylate/Caprate, Polyglyceryl-3 Methylglucose Distearate, Caprylic/Capric Triglyceride, Pentylene Glycol, Propanediol, Polyglyceryl-3 Distearate, Cyclohexasiloxane, 1,2-Hexanediol, Butylene Glycol, Diphenyl Dimethicone, Diphenylsiloxy Phenyl Trimethicone, Cetearyl Olivate, Sorbitan Olivate, Hydrogenated Coco-Glycerides, Cetearyl Alcohol, Glyceryl Stearate, Polymethylsilsesquioxane, Glucose, Chlorella Vulgaris Extract, Butyrospermum Parkii Butter, Hydroxyacetophenone, Sodium Polyacrylate Starch, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Fructose, Fructooligosaccharides, Tromethamine, Parfum, Glyceryl Stearate Citrate, Panthenol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrogenated Lecithin, Sodium Phytate, Xanthan Gum, Stearic Acid, Hyaluronic Acid, Ethylhexylglycerin, Beta-Glucan, Ceramide NP, Hydrolyzed Hyaluronic Acid, Ceramide Ns, Cholesterol, Phytosphingosine, Sodium Hyaluronate, Ceramide AP, Ceramide As, Ceramide EOP
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.
Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).
In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).
Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.
Shea butter also contains vitamins A and E which may contribute to antioxidant activity.
While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Cetearyl Olivate is a plant-derived emulsifier and texture enhancer. It helps keep the oil and water phases from separating so your formulas stay stable.
You'll likely see it combined with Sorbitan Olivate (together sold as the trade name Olivem 1000). This combination generates a liquid crystal structure that closely resemble the lipid organization of the stratum corneum.
These "skin-like" liquid crystals improve skin barrier integrity and promote the delivery of actives into the skin.
This ingredient is well-tolerated and has no significant sensitization data.
Because it is derived from the fatty acids in olive oil, this ingredient may not be fungal acne safe.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Polymethylsilsesquioxane is a silicone used as a film forming agent.
When applied to the skin, this ingredient creates an invisible film on the surface. This film still allows oxygen to pass through, but prevents moisture from escaping. This can help condition and hydrate the skin. It also leaves a silky feel when applied.
Polymethylsilsesquioxane has not been shown to clog pores. It has been deemed safe to use up to 55%, but most cosmetics use much less.
If you have concerns about using this ingredient, we recommend speaking with a professional.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.
This ingredient is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.
This ingredient is also known as part of Olivem 1000, with Cetearyl Olivate being the other part.
According to a manufacturer, this ingredient helps preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria.
Please note, having a healthy microbiome is different from fungal acne; a healthy microbiome includes small amounts of yeast that normally live on your skin without causing problems.
Fungal acne happens when one type of yeast (Malassezia) grows out of control. This is usually because it's feeding on certain oils or fatty acids. Due to the olive oil base, this ingredient may not be fungal acne safe.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!