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The INKEY List Tripeptide Plumping Lip Balm Versus The INKEY List Collagen Peptide Serum

The INKEY List Tripeptide Plumping Lip Balm Versus The INKEY List Collagen Peptide Serum This anti-aging lip moisturizer is formulated around Squalane and Palmitoyl Tripeptide-1 to soften the look of wrinkles and hydrate lips. This anti-aging serum is formulat

The INKEY List Tripeptide Plumping Lip Balm Versus The INKEY List Collagen Peptide Serum

This anti-aging lip moisturizer is formulated around Squalane and Palmitoyl Tripeptide-1 to soften the look of wrinkles and hydrate lips.

This anti-aging serum is formulated around Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Ricinus Communis Seed Oil

Hydroxystearic/Linolenic/Oleic Polyglycerides

Glyceryl Rosinate

Theobroma Grandiflorum Seed Butter

Butyrospermum Parkii Butter

Ethylhexyl Palmitate

Candelilla Cera

Mangifera Indica Seed Butter

Orbignya Oleifera Seed Oil

Squalane

Cetearyl Ethylhexanoate

Hydrogenated Olive Oil

Salvia Hispanica Seed Oil

Caprylic/Capric Triglyceride

Glyceryl Behenate

Olea Europaea Oil Unsaponifiables

Tribehenin

Sorbitan Isostearate

Tocopherol

Portulaca Pilosa Extract

Trihydroxystearin

Helianthus Annuus Seed Oil

Sucrose Cocoate

Brassica Alba Sprout Extract

Sodium Hyaluronate

Palmitoyl Tripeptide-1

Palmitoyl Tripeptide-38

Glucomannan

Ricinus Communis Seed Oil, Hydroxystearic/Linolenic/Oleic Polyglycerides, Glyceryl Rosinate, Theobroma Grandiflorum Seed Butter, Butyrospermum Parkii Butter, Ethylhexyl Palmitate, Candelilla Cera, Mangifera Indica Seed Butter, Orbignya Oleifera Seed Oil, Squalane, Cetearyl Ethylhexanoate, Hydrogenated Olive Oil, Salvia Hispanica Seed Oil, Caprylic/Capric Triglyceride, Glyceryl Behenate, Olea Europaea Oil Unsaponifiables, Tribehenin, Sorbitan Isostearate, Tocopherol, Portulaca Pilosa Extract, Trihydroxystearin, Helianthus Annuus Seed Oil, Sucrose Cocoate, Brassica Alba Sprout Extract, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-38, Glucomannan

Water

Glycerin

Butylene Glycol

Propanediol

Phenoxyethanol

Hydroxyethylcellulose

Sodium Phytate

Citric Acid

Leuconostoc/Radish Root Ferment Filtrate

Carbomer

Hyaluronic Acid

Sodium Lactate

Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine

Palmitoyl Dipeptide-5 Diaminohydroxybutyrate

Polysorbate 20

Polysorbate 60

Disodium Phosphate

Sodium Phosphate

Palmitoyl Tetrapeptide-7

Water, Glycerin, Butylene Glycol, Propanediol, Phenoxyethanol, Hydroxyethylcellulose, Sodium Phytate, Citric Acid, Leuconostoc/Radish Root Ferment Filtrate, Carbomer, Hyaluronic Acid, Sodium Lactate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate, Polysorbate 20, Polysorbate 60, Disodium Phosphate, Sodium Phosphate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.

That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.

Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.

In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.

Human clinical data is promising, but modest:

A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.

A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.

You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.

Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Tocopherol is a fat-soluble antioxidant known as Vitamin E.
  4. 04You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damag…
  5. 05Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
  6. 06It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
  7. 07This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
  8. 08This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
  9. 09In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
  10. 10Concentrations usually range from 0.1-1% in most leave-on products.
Source · skinsort.com
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Product index

Related product references

Product

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Madara Derma Collagen Peptide Serum Ingredients in Madara Derma Collagen Peptide Serum explained: benefits, concerns, and detailed analysis of 28 ingredients including Aloe Barbadensis Leaf…

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Product

OWRN Collagen & Peptide Serum

OWRN Collagen & Peptide Serum OWRN Collagen & Peptide Serum ingredients explained: Water, Methylpropanediol, Glycerin, Butylene Glycol, Dipropylene Glycol, Propanediol, Polysorbate 20, Carb…

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Comparison edit

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