Skin science article
The INKEY List Tripeptide Plumping Lip Balm Versus The INKEY List Collagen Peptide Serum
The INKEY List Tripeptide Plumping Lip Balm Versus The INKEY List Collagen Peptide Serum This anti-aging lip moisturizer is formulated around Squalane and Palmitoyl Tripeptide-1 to soften the look of wrinkles and hydrate lips. This anti-aging serum is formulat
The INKEY List Tripeptide Plumping Lip Balm Versus The INKEY List Collagen Peptide Serum
This anti-aging lip moisturizer is formulated around Squalane and Palmitoyl Tripeptide-1 to soften the look of wrinkles and hydrate lips.
This anti-aging serum is formulated around Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Ricinus Communis Seed Oil
Hydroxystearic/Linolenic/Oleic Polyglycerides
Glyceryl Rosinate
Theobroma Grandiflorum Seed Butter
Butyrospermum Parkii Butter
Ethylhexyl Palmitate
Candelilla Cera
Mangifera Indica Seed Butter
Orbignya Oleifera Seed Oil
Squalane
Cetearyl Ethylhexanoate
Hydrogenated Olive Oil
Salvia Hispanica Seed Oil
Caprylic/Capric Triglyceride
Glyceryl Behenate
Olea Europaea Oil Unsaponifiables
Tribehenin
Sorbitan Isostearate
Tocopherol
Portulaca Pilosa Extract
Trihydroxystearin
Helianthus Annuus Seed Oil
Sucrose Cocoate
Brassica Alba Sprout Extract
Sodium Hyaluronate
Palmitoyl Tripeptide-1
Palmitoyl Tripeptide-38
Glucomannan
Ricinus Communis Seed Oil, Hydroxystearic/Linolenic/Oleic Polyglycerides, Glyceryl Rosinate, Theobroma Grandiflorum Seed Butter, Butyrospermum Parkii Butter, Ethylhexyl Palmitate, Candelilla Cera, Mangifera Indica Seed Butter, Orbignya Oleifera Seed Oil, Squalane, Cetearyl Ethylhexanoate, Hydrogenated Olive Oil, Salvia Hispanica Seed Oil, Caprylic/Capric Triglyceride, Glyceryl Behenate, Olea Europaea Oil Unsaponifiables, Tribehenin, Sorbitan Isostearate, Tocopherol, Portulaca Pilosa Extract, Trihydroxystearin, Helianthus Annuus Seed Oil, Sucrose Cocoate, Brassica Alba Sprout Extract, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-38, Glucomannan
Water
Glycerin
Butylene Glycol
Propanediol
Phenoxyethanol
Hydroxyethylcellulose
Sodium Phytate
Citric Acid
Leuconostoc/Radish Root Ferment Filtrate
Carbomer
Hyaluronic Acid
Sodium Lactate
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
Palmitoyl Dipeptide-5 Diaminohydroxybutyrate
Polysorbate 20
Polysorbate 60
Disodium Phosphate
Sodium Phosphate
Palmitoyl Tetrapeptide-7
Water, Glycerin, Butylene Glycol, Propanediol, Phenoxyethanol, Hydroxyethylcellulose, Sodium Phytate, Citric Acid, Leuconostoc/Radish Root Ferment Filtrate, Carbomer, Hyaluronic Acid, Sodium Lactate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate, Polysorbate 20, Polysorbate 60, Disodium Phosphate, Sodium Phosphate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.
That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.
Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.
In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.
Human clinical data is promising, but modest:
A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.
A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.
You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.
Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.