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Skin science article

The Ordinary Caffeine Solution 5% + EGCG Versus Biossance Squalane + Peptide Eye Gel

The Ordinary Caffeine Solution 5% + EGCG Versus Biossance Squalane + Peptide Eye Gel This calming eye moisturizer is formulated around Caffeine and Epigallocatechin Gallatyl Glucoside to calm redness and soften the look of wrinkles. This anti-aging eye moistur

The Ordinary Caffeine Solution 5% + EGCG Versus Biossance Squalane + Peptide Eye Gel

This calming eye moisturizer is formulated around Caffeine and Epigallocatechin Gallatyl Glucoside to calm redness and soften the look of wrinkles.

This anti-aging eye moisturizer is formulated around Squalane and Niacinamide to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Caffeine

Maltodextrin

Glycerin

Propanediol

Epigallocatechin Gallatyl Glucoside

Gallyl Glucoside

Hyaluronic Acid

Oxidized Glutathione

Melanin

Glycine Soja Seed Extract

Pentylene Glycol

Hydroxyethylcellulose

Polyacrylate Crosspolymer-6

Xanthan Gum

Lactic Acid

Dehydroacetic Acid

Trisodium Ethylenediamine Disuccinate

Propyl Gallate

Dimethyl Isosorbide

Benzyl Alcohol

1,2-Hexanediol

Ethylhexylglycerin

Phenoxyethanol

Caprylyl Glycol

Water, Caffeine, Maltodextrin, Glycerin, Propanediol, Epigallocatechin Gallatyl Glucoside, Gallyl Glucoside, Hyaluronic Acid, Oxidized Glutathione, Melanin, Glycine Soja Seed Extract, Pentylene Glycol, Hydroxyethylcellulose, Polyacrylate Crosspolymer-6, Xanthan Gum, Lactic Acid, Dehydroacetic Acid, Trisodium Ethylenediamine Disuccinate, Propyl Gallate, Dimethyl Isosorbide, Benzyl Alcohol, 1,2-Hexanediol, Ethylhexylglycerin, Phenoxyethanol, Caprylyl Glycol

Aloe Barbadensis Leaf Juice

Squalane

Niacinamide

Panthenol

Chondrus Crispus Extract

Malus Domestica Fruit Cell Culture Extract

Acetyl Tetrapeptide-5

Acetyl Hexapeptide-8

Tocopherol

Cucumis Sativus Fruit Extract

Tetrahexyldecyl Ascorbate

Camellia Sinensis Leaf Extract

Lycium Barbarum Fruit Extract

Lycopene

Vitis Vinifera Skin Extract

Sodium Hyaluronate

Acacia Senegal Gum

Dimethicone Crosspolymer

Carbomer

Ethyl Lauroyl Arginate Hcl

Lecithin

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Silica

Potassium Sorbate

Citric Acid

Water, Aloe Barbadensis Leaf Juice, Squalane, Niacinamide, Glycerin, Panthenol, Chondrus Crispus Extract, Malus Domestica Fruit Cell Culture Extract, Acetyl Tetrapeptide-5, Acetyl Hexapeptide-8, Tocopherol, Pentylene Glycol, Cucumis Sativus Fruit Extract, Tetrahexyldecyl Ascorbate, Camellia Sinensis Leaf Extract, Lycium Barbarum Fruit Extract, Lycopene, Vitis Vinifera Skin Extract, Sodium Hyaluronate, Caffeine, Acacia Senegal Gum, Dimethicone Crosspolymer, Xanthan Gum, Carbomer, Ethyl Lauroyl Arginate Hcl, Lecithin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Silica, Phenoxyethanol, Potassium Sorbate, Citric Acid, Caprylyl Glycol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.

As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.

Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.

You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.

Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.

Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Niacinamide
  3. 03Squalane
  4. 04Glycerin
  5. 05Cetyl Ethylhexanoate
  6. 06Sodium Acrylates Copolymer
  7. 07Phenoxyethanol
  8. 08Caffeine
  9. 09Tetrahexyldecyl Ascorbate
  10. 10Lecithin
  11. 11Synthetic Fluorphlogopite
  12. 12Polyglyceryl-3 Laurate
  13. 13Pullulan
  14. 14Ethylhexylglycerin
  15. 15Hippophae Rhamnoides Fruit Oil
  16. 16Sodium Gluconate
  17. 17Methyl Glucose Sesquistearate
  18. 18Caprylyl Glycol
  19. 19Tin Oxide
  20. 20Acetyl Hexapeptide-8
Source · skinsort.com
02

Product index

Related product references

Product

Biossance Squalane + Peptide Eye Gel

Biossance Squalane + Peptide Eye Gel Ingredients in Biossance Squalane + Peptide Eye Gel explained: benefits, concerns, and detailed analysis of 32 ingredients including Water, Aloe Barbade…

Source: skinsort.comView reference →

Product

BIOSSANCE Squalane + Peptide Eye Gel

BIOSSANCE Squalane + Peptide Eye Gel BIOSSANCE Squalane + Peptide Eye Gel ingredients explained: Water/Aqua, Aloe Barbadensis Leaf Juice*, Squalane, Niacinamide, Glycerin, Panthenol, Chondr…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side