Skin science article
The Ordinary Natural Moisturizing Factors + HA Versus Dermatica Nourishing Ceramide + Peptide Moisturizer
The Ordinary Natural Moisturizing Factors + HA Versus Dermatica Nourishing Ceramide + Peptide Moisturizer This barrier-repair moisturizer is formulated around Sodium Hyaluronate and Arginine to strengthen the skin barrier and hydrate skin. This barrier-repair
The Ordinary Natural Moisturizing Factors + HA Versus Dermatica Nourishing Ceramide + Peptide Moisturizer
This barrier-repair moisturizer is formulated around Sodium Hyaluronate and Arginine to strengthen the skin barrier and hydrate skin.
This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Caprylic/Capric Triglyceride
Cetyl Alcohol
Propanediol
Stearyl Alcohol
Glycerin
Sodium Hyaluronate
Arginine
Aspartic Acid
Glycine
Alanine
Serine
Valine
Isoleucine
Proline
Threonine
Histidine
Phenylalanine
Glucose
Maltose
Fructose
Trehalose
Sodium PCA
PCA
Sodium Lactate
Urea
Allantoin
Linoleic Acid
Oleic Acid
Phytosteryl Canola Glycerides
Palmitic Acid
Stearic Acid
Lecithin
Triolein
Tocopherol
Carbomer
Isoceteth-20
Polysorbate 60
Sodium Chloride
Citric Acid
Trisodium Ethylenediamine Disuccinate
Pentylene Glycol
Triethanolamine
Sodium Hydroxide
Phenoxyethanol
Chlorphenesin
Water, Caprylic/Capric Triglyceride, Cetyl Alcohol, Propanediol, Stearyl Alcohol, Glycerin, Sodium Hyaluronate, Arginine, Aspartic Acid, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Glucose, Maltose, Fructose, Trehalose, Sodium PCA, PCA, Sodium Lactate, Urea, Allantoin, Linoleic Acid, Oleic Acid, Phytosteryl Canola Glycerides, Palmitic Acid, Stearic Acid, Lecithin, Triolein, Tocopherol, Carbomer, Isoceteth-20, Polysorbate 60, Sodium Chloride, Citric Acid, Trisodium Ethylenediamine Disuccinate, Pentylene Glycol, Triethanolamine, Sodium Hydroxide, Phenoxyethanol, Chlorphenesin
Cetearyl Alcohol
Butyrospermum Parkii Butter
C12-15 Alkyl Benzoate
Niacinamide
Vitis Vinifera Oil
Dimethicone
Panthenol
Sorbitan Stearate
Squalane
Tocopheryl Acetate
Butylene Glycol
Polyacrylate Crosspolymer-6
Sodium Lauroyl Lactylate
Centella Asiatica Extract
Ethylhexylglycerin
Ceramide NP
Ceramide AP
Phytosphingosine
Cholesterol
Polysorbate 20
Xanthan Gum
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Ceramide EOP
Water, Cetearyl Alcohol, Glycerin, Butyrospermum Parkii Butter, C12-15 Alkyl Benzoate, Niacinamide, Vitis Vinifera Oil, Dimethicone, Panthenol, Sorbitan Stearate, Squalane, Tocopheryl Acetate, Phenoxyethanol, Butylene Glycol, Polyacrylate Crosspolymer-6, Sodium Lauroyl Lactylate, Centella Asiatica Extract, Ethylhexylglycerin, Sodium Hyaluronate, Trisodium Ethylenediamine Disuccinate, Citric Acid, Carbomer, Ceramide NP, Ceramide AP, Phytosphingosine, Cholesterol, Polysorbate 20, Xanthan Gum, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Trisodium Ethylenediamine Disuccinate is used to help stabilize a product.
It is a chelating agent, meaning it helps prevent metal ions from binding to other ingredients. This prevents unwanted reactions in products. Metal ions can come into a product via the water ingredient. They are found in trace amounts and are not known to be harmful.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!