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The Ordinary Retinol 0.2% In Squalane Versus Paula's Choice Skin Balancing Super Antioxidant Concentrate Serum

The Ordinary Retinol 0.2% In Squalane Versus Paula's Choice Skin Balancing Super Antioxidant Concentrate Serum This anti-aging serum is formulated around Squalane and Retinol to soften the look of wrinkles and refine skin texture. This anti-aging serum is form

The Ordinary Retinol 0.2% In Squalane Versus Paula's Choice Skin Balancing Super Antioxidant Concentrate Serum

This anti-aging serum is formulated around Squalane and Retinol to soften the look of wrinkles and refine skin texture.

This anti-aging serum is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Squalane

Caprylic/Capric Triglyceride

Simmondsia Chinensis Seed Oil

Retinol

Solanum Lycopersicum Fruit Extract

Rosmarinus Officinalis Leaf Extract

Hydroxymethoxyphenyl Decanone

BHT

Squalane, Caprylic/Capric Triglyceride, Simmondsia Chinensis Seed Oil, Retinol, Solanum Lycopersicum Fruit Extract, Rosmarinus Officinalis Leaf Extract, Hydroxymethoxyphenyl Decanone, BHT

Cyclopentasiloxane

Isododecane

Dimethicone Crosspolymer

Neopentyl Glycol Diheptanoate

Cyclohexasiloxane

Tocopheryl Acetate

Retinyl Palmitate

Tetrahexyldecyl Ascorbate

Astaxanthin

Bisabolol

Chamomilla Recutita Flower Extract

Camellia Sinensis Leaf Extract

Salix Alba Bark Extract

Vitis Vinifera Seed Extract

Ginkgo Biloba Leaf Extract

Calluna Vulgaris Flower Extract

Vaccinium Macrocarpon Fruit Extract

Rubus Idaeus Fruit Extract

Betula Alba Bark Extract

Glycine Soja Oil

Silica

Phenoxyethanol

Cyclopentasiloxane, Isododecane, Dimethicone Crosspolymer, Neopentyl Glycol Diheptanoate, Cyclohexasiloxane, Caprylic/Capric Triglyceride, Tocopheryl Acetate, Retinyl Palmitate, Retinol, Tetrahexyldecyl Ascorbate, Astaxanthin, Bisabolol, Chamomilla Recutita Flower Extract, Camellia Sinensis Leaf Extract, Salix Alba Bark Extract, Vitis Vinifera Seed Extract, Ginkgo Biloba Leaf Extract, Calluna Vulgaris Flower Extract, Vaccinium Macrocarpon Fruit Extract, Rubus Idaeus Fruit Extract, Betula Alba Bark Extract, Glycine Soja Oil, Silica, Phenoxyethanol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Retinol is one of the most studied anti-aging ingredients in skincare (and for good reason!).

It's a form of vitamin A that your skin converts into Retinoic Acid, the active molecule that actually does the work in your cells.

That conversion happens in two steps: your skin first turns Retinol into Retinaldehyde (also called Retinal), then turns Retinaldehyde into Retinoic Acid.

Retinol is converted to biologically active retinoic acid via retinaldehyde by dehydrogenases in a two-step oxidation process.

Each step is a little "upgrade" toward the active form which is part of why Retinol is gentler than prescription Retinoic Acid; your skin does the work gradually. This also explains where Retinol sits in the retinoid family.

Here is the retinoid family ranked roughly by strength: Retinyl Esters (like Retinyl Palmitate) < Retinol < Retinaldehyde < Retinoic Acid.

Retinoid activity increases in that order, while tolerance runs in reverse; retinyl esters are the gentlest and retinoic acid the most irritating.

The more conversion steps an ingredient needs, the gentler (and slower) it tends to be, so Retinol lands in a nice middle spot. It's more effective than the esters, gentler than prescription options.

Once it becomes Retinoic Acid, it binds to receptors inside your cells' nuclei (called RARs and RXRs). These receptor pairs bind to specific DNA motifs called retinoic acid response elements and act like switches that turn certain genes on or off.

In practice, this means a few things happen in a formula. It:

That last two are worth a closer look.

A study that tested Retinol directly (not just prescription Retinoic Acid) found that four weeks of retinol thickened the epidermis and switched on the genes for Collagen I and Collagen III, with more procollagen I and III showing up in the skin. And after twelve weeks, facial wrinkles were visibly reduced.

Retinoids more broadly stimulate the skin's synthesis of hyaluronan and other glycosaminoglycans, part of what gives skin a plumper, more hydrated look over time.

So even the gentler OTC form is doing real structural work (not just sitting on the surface).

It's also worth knowing Retinol isn't only a wrinkle ingredient; it can help with uneven tone, dark spots, rough texture, and the look of pores as well because it speeds up turnover and influences pigment.

The research backs this up as well.

A pooled analysis of six clinical studies found that 0.1% stabilized retinol improved all signs of photoaging versus vehicle as early as week 4 and through 12 weeks, with only a few mild cases of irritation.

Another study comparing concentrations found that 0.3% and 1% Retinol were similarly effective at remodeling photodamaged skin, but 0.3% caused fewer adverse reactions when used daily (a useful reminder that more isn't always better).

Retinol is about tenfold less potent than Retinoic Acid. This is why it works as a gentler, non-prescription option that builds results over time.

Typical concentrations range from 0.1-1%, with 0.1% to 0.3% being a well-supported sweet spot for visible benefits with good tolerability.

One quirk worth mentioning: Retinol is famously unstable.

It's highly sensitive to light and oxygen, and UV exposure breaks it down into a range of degradation products.

Real-world testing bears this out, with retinoid content in some products dropping anywhere from 0% to 80% after six months at room temperature, and even more at higher temperatures.

This is why good formulations lean on opaque, air-tight packaging (think tubes and pumps, not clear jars) and often "encapsulate" the Retinol to shield it.

Signs of oxidation include your product turning yellow or smelling "off". Keeping it somewhere cool and dark, and using it up within a few months of opening helps it stay effective.

The most common side effects are mild and temporary: usually some dryness, redness, or light peeling as your skin adjusts. These tend to settle with consistent and lower-frequency use.

Like all retinoids, Retinol works best with nightly use, a good moisturizer, and daytime sunscreen.

The "ramp up" method works well: start with Retinol once a week to give your skin time to adjust, which keeps irritation low. Slowly add more nights until you reach your goal frequency once your skin feels comfortable.

Retinoids also make your skin more sensitive to the sun in the first few weeks, so wear sunscreen every morning and protect your skin from direct sun while you build up tolerance.

One safety note: topical Retinoids aren't recommended during pregnancy or breastfeeding. Systemic absorption from creams is low but because high oral vitamin A is a known teratogen and topical safety data are limited, most clinicians recommend stopping retinoids when pregnant or trying to conceive.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
  4. 04As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
  5. 05It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
  6. 06A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
  7. 07Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient.
  8. 08It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation.
  9. 09A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.
  10. 10In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.
  11. 11You'll likely see use concentrations quite low, usually 0.1-0.2%.
  12. 12Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.
  13. 13Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  14. 14Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  15. 15Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  16. 16Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
  17. 17This ingredient mainly works behind the scenes and helps with:
  18. 18On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
  19. 19One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too st…
  20. 20Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
Source · skinsort.com
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Product index

Related product references

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Comparison edit

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